Which CD8+ T-cells in asthma? Attacking or defending?

Baraldo Simonetta, Turato Graziella, Cosio Manuel G., Saetta Marina

Source: Eur Respir J 2016; 48: 287-290
Journal Issue: August
Disease area: Airway diseases

Full text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Baraldo Simonetta, Turato Graziella, Cosio Manuel G., Saetta Marina. Which CD8+ T-cells in asthma? Attacking or defending?. Eur Respir J 2016; 48: 287-290

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
T-cells in COPD: harmful or protective?
Source: Annual Congress 2012 - ERS COPD Research Award Ceremony (supported by Boehringer Ingelheim) followed by the Hot Topic "It takes two to tango: innate and adaptive immunity in COPD"
Year: 2012


CD8+ Tc2 cells: underappreciated contributors to severe asthma
Source: Eur Respir Rev, 28 (154) 190092; 10.1183/16000617.0092-2019
Year: 2019



Late Breaking Abstract - Characterization of the immunological profile of COVID-19 patients and correlation of CD4+ and CD8+ T lymphocytes with disease severity during hospitalization.
Source: Virtual Congress 2021 – Late breaking basic and translational science of SARS-Cov2 and COVID-19
Year: 2021



Type-2 CD8+ T lymphocytes responsive to PGD2/LTE4 in severe eosinophilic asthma
Source: International Congress 2018 – Advanced profiling of immune cells in chronic lung diseases
Year: 2018




Decreased regulation of lung CD8+ T cells by virally-infected macrophages in COPD: Role of PD1/PDL1 axis
Source: International Congress 2015 – Advances from translational research in respiratory infections
Year: 2015

CD4+ and CD8+ T lymphocytes display a Th2/Tc2 cytokine profile in COPD
Source: Eur Respir J 2004; 24: Suppl. 48, 319s
Year: 2004

Inflammatory process of CD8+ CD28- T cells in induced sputum from asthmatic patients
Source: Eur Respir J 2005; 26: Suppl. 49, 25s
Year: 2005

PAS-1, an Ascaris suum protein, modulates allergic airway inflammation via CD8+ and CD4+ CD25+ T cells
Source: Annual Congress 2009 - Animal models of airways inflammation
Year: 2009


Modification of surface antigens in blood CD8+ T-lymphocytes in COPD: effects of smoking
Source: Eur Respir J 2007; 29: 42-50
Year: 2007



Evidence for cell mediated immune dysfunction in the COPD lung: The role of cytotoxic CD4+ T cells
Source: International Congress 2015 – Viral infections: basic research and clinical perspective
Year: 2015

Increase of both blood CXCR3+ and CCR4+ helper T cells associated with severity of asthma
Source: Annual Congress 2005 - Inflammation and remodelling in allergy and asthma
Year: 2005


Characteristics of fatal asthma: CD8 positive T cells producing IFN-γ and IL-18 were recruited into small airways in fatal asthma
Source: Annual Congress 2009 - COPD and asthma - from the cell to the clinic
Year: 2009


Regulatory T-lymphocytes in asthma
Source: Eur Respir J 2005; 26: 918-932
Year: 2005



Expression of Th1, Th2 and Th17 cytokines in CD4+ T cells in peripheral blood of asthma patients
Source: International Congress 2014 – Rationale behind respiratory drug development
Year: 2014

Control of bystander T-cells responses by CD4+CD25+ cytolytic regulatory T-cells
Source: Eur Respir J 2005; 26: Suppl. 49, 24s
Year: 2005

Upregulation of CD4+ and CD8+ cells expressing CX3CR1 in asthmatics
Source: Annual Congress 2006 - Towards understanding the pathogenesis of asthma
Year: 2006


Differentiate late-onset asthma and COPD by CD4+ T memory cells in peripheral blood
Source: International Congress 2015 – Modulating the immune system in COPD and asthma
Year: 2015

IL-10-producing CD4+ T cells are essential for the development of airway hyperresponsiveness
Source: Annual Congress 2004 - Modulation of the allergic response in animal models
Year: 2004