ADEPT-derived, U-BIOPRED validated asthma clinical clusters with Th2 and non-Th2 phenotypes

M. Loza, P. Silkoff, V. Susilic, A. Rowe, I. Adcock, C. Auffray, K. F. Chung, R. Djukanovic, P. Sterk, F. Baribaud (Spring House, United States Of America; London, Southampton, United Kingdom; Lyon, France; Amsterdam, Netherlands)

Source: International Congress 2014 – Novel targets and drugs for asthma and COPD
Session: Novel targets and drugs for asthma and COPD
Session type: Oral Presentation
Number: 4859
Disease area: Airway diseases

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Loza, P. Silkoff, V. Susilic, A. Rowe, I. Adcock, C. Auffray, K. F. Chung, R. Djukanovic, P. Sterk, F. Baribaud (Spring House, United States Of America; London, Southampton, United Kingdom; Lyon, France; Amsterdam, Netherlands). ADEPT-derived, U-BIOPRED validated asthma clinical clusters with Th2 and non-Th2 phenotypes. Eur Respir J 2014; 44: Suppl. 58, 4859

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Th2 subsetting of U-BIOPRED asthma subjects based on airway transciptomic profiles
Source: International Congress 2015 – Advances in the future treatment of severe asthma
Year: 2015


Mutually exclusive Th2 and Th17 bronchial gene expression signatures are associated with eosinophilia in asthma
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014

Gene set variation analysis of mRNA expression in bronchial biopsies from the U-BIOPRED asthma study
Source: International Congress 2014 – Novel approaches and evidence for drug development in respiratory diseases
Year: 2014


The first U-BIOPRED sputum handprint of severe asthma
Source: International Congress 2015 – Respiratory translational research: novel mechanisms, diagnostic markers and Space Odyssey
Year: 2015



TSLP as biomarker in asthma patients
Source: International Congress 2015 – Systemic and airway biomarkers
Year: 2015


The first U-BIOPRED blood handprint of severe asthma
Source: International Congress 2015 – Promising novel findings in translational pulmonary research
Year: 2015


Peripheral pathological ILC2: An inflammatory indicator for the assessment of asthma control in clinics
Source: International Congress 2016 – Asthma: mechanisms and biomarkers that promote clinical understanding
Year: 2016


Levels of cytokines, sCD31 and expression of CD38 in patients with bronchial asthma of various severity out of a disease exacerbation
Source: International Congress 2014 – Biomarkers of asthma and clinical immunology
Year: 2014

Autoreactivity in patients with combined COPD and asthma phenotype
Source: International Congress 2014 – Novel approaches to human studies in allergy and asthma
Year: 2014


Characterisation of a steroid-insensitive severe asthma model
Source: International Congress 2014 – Animal models in respiratory drug development
Year: 2014

Epidemiological, clinical and morphological features of allergic rhinitis and bronchial asthma in patients of different ages
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014

Discrimination of bronchial inflammatory phenotype of asthmatic patients by using the electronic nose
Source: Annual Congress 2013 –Origins and diagnosis of asthma
Year: 2013



Expression of genes associated with neurogenic inflammation in pediatric asthma
Source: Annual Congress 2013 –Monitoring asthma: genes, cells and molecules
Year: 2013


Characteristics of the adult corticosteroid-dependent severe asthma in UBIOPRED consortium
Source: International Congress 2014 – Novel targets and drugs for asthma and COPD
Year: 2014

TLR-3 triggered exacerbation of experimental asthma depends on IL-17 producing NK cells
Source: International Congress 2014 – TH17 and other acute asthmatic responses
Year: 2014

Characteristics of IL-25 and allergen-induced airways fibrosis in a murine model of asthma
Source: International Congress 2015 – The immunology of allergic airway disease
Year: 2015


Pharmacogenetics in severity of bronchial hyperresponsiveness in asthma
Source: Annual Congress 2013 –Genetic factors in airway development and disease
Year: 2013

Investigating the role of BAFF in murine models of allergic asthma
Source: International Congress 2014 – Paediatric asthma: markers and molecules
Year: 2014

Preventative administration of IL-27 improves airway inflammation of ovalbumin –induced asthma mice model via both STAT1 and GADD45γ/p38MAPK pathways
Source: International Congress 2016 – Pharmacological intervention in humans and murine models of asthma
Year: 2016


Lung specific induction of Wnt-1 has a prophylactic and therapeutic effect on the development of an allergic airway disease
Source: Annual Congress 2013 –Murine models of lung immunology
Year: 2013