A role for the WFDC protein, WAP2, in regulation of innate host defence in the lung

A. Glasgow, D. Small, A. Scott, D. McLean, N. Camper, U. Hamid, S. Hegarty, C. O'Kane, D. McAuley, F. Lundy, S. Elborn, S. Weldon, C. Taggart (Belfast, United Kingdom)

Source: International Congress 2014 – New studies into pulmonary proteases and antiproteases
Session: New studies into pulmonary proteases and antiproteases
Session type: Oral Presentation
Number: 4850
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. Glasgow, D. Small, A. Scott, D. McLean, N. Camper, U. Hamid, S. Hegarty, C. O'Kane, D. McAuley, F. Lundy, S. Elborn, S. Weldon, C. Taggart (Belfast, United Kingdom). A role for the WFDC protein, WAP2, in regulation of innate host defence in the lung. Eur Respir J 2014; 44: Suppl. 58, 4850

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Eotaxin-3 exerts innate host defense activities that are modulated by mast cell proteases
Source: International Congress 2015 – Immune mechanisms in the human lung
Year: 2015

LSC 2014 abstract - Targeting of microRNAs can restore innate anti-viral response in asthma
Source: International Congress 2014 – Novel epigenetic regulators for targeting via nanomedicine
Year: 2014


Imbalance of immune response functional phenotype and alveolar macrophages phenotype in COPD
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014


Different roles for PI3Kgamma and δ in asthma
Source: International Congress 2014 – Animal models: asthma, COPD and beyond
Year: 2014

Expression of CX3CL1 and CX3CR1 in human asthmatic lung in relation to cell survival
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014

Evidence for a novel kit adhesion domain mediating human mast cell adhesion to structural airway cells
Source: International Congress 2014 – Cell biology 2014
Year: 2014

The expression of the negative regulator of gene transcription SOCS3 as the crucial marker in the asthma pathogenesis
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014

Modulation of PD-1 and PD-L1 expression in response to acute viral infection of human lung tissue
Source: International Congress 2014 – Cell biology 2014
Year: 2014

Mapping the cellular source and role of IL-22 in murine lung infections
Source: International Congress 2015 – Viral infections: basic research and clinical perspective
Year: 2015

Hyperoxia impairs the inflammatory response of alveolar macrophages to multiple Toll-like receptor ligands associated with bacterial infection
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014

Role of the immunoregulatory microRNA miR-146a in the innate immune response to rhinovirus infection
Source: Annual Congress 2013 –Viral infections: what is new?
Year: 2013


The role of chemokine receptors in the aberrant migration of COPD neutrophils
Source: International Congress 2014 – Cell biology 2014
Year: 2014

Vitamin D increases anti-microbial activity in human airway epithelial cells
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

HMGB1 expression and function in the allergic airway immune response
Source: International Congress 2014 – Exploring molecular mechanisms of allergy and asthma in animal models
Year: 2014

Anti-inflammatory action of Gibberellin in lung epithelial cells is mediated by modification of NF-κB related kinase expression
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014


Modulation of neutrophil functionalities by indacaterol and their relevance for chronic lung diseases
Source: International Congress 2014 – Translational studies in COPD
Year: 2014

LATE-BREAKING ABSTRACT: Inhibition of Pim1 kinase augments the anti-viral response to rhinovirus infection.
Source: International Congress 2014 – COPD exacerbations
Year: 2014

The role of Clara cell senescence in the pathogenesis of COPD
Source: International Congress 2014 – Effect of cigarette smoke on cell behaviour: cell biology, signalling and senescence
Year: 2014

Induction of galectin-9 production by viral infection in the lung
Source: International Congress 2015 – The multiple faces of host defense
Year: 2015

Validating SIK as a novel COPD target using four different human systems
Source: International Congress 2014 – Translational studies in COPD
Year: 2014