Inhibition of the Arp2/3 complex inhibits lung myofibroblast differentiation in vitro and attenuates bleomycin-induced pulmonary fibrosis in mice Source: International Congress 2019 – Extracellular matrix formation and remodelling in physiology and disease Year: 2019
Inhibition of histone acetyltransferases attenuates cytokine and LPS-induced up-regulation of arginase in rat alveolar macrophages Source: Eur Respir J 2006; 28: Suppl. 50, 662s Year: 2006
Oxidative stress-mediated decrease in histone deacetylase activity is attenuated by N-acetyl-L-cysteine but not by Iκ-B kinase inhibition in alveolar epithelial cells Source: Eur Respir J 2004; 24: Suppl. 48, 29s Year: 2004
Tankyrase(TNKS) inhibiting autophagy promotes the TGF-ß induced EMT process in vitro and Bleomycin(BLM) induced pulmonary fibrosis in rats Source: International Congress 2019 – Translational aspects of idiopathic pulmonary fibrosis Year: 2019
Cell specific gene transfer of hepatocyte growth factor reduces bleomycin-induced lung fibrosis by inhibition of partial EMT Source: Annual Congress 2008 - Vascular and interstitial remodelling in chronic lung disease: therapeutic interventions on the horizon Year: 2008
Bromodomain inhibitor JQ1 attenuates TGF-beta-suppressed SOD2 expression and reduces proliferation in human primary pulmonary fibroblasts Source: Annual Congress 2013 –The multiple faces of stress in lung injury Year: 2013
TSC1/mTOR pathway promotes hypoxia-induced pulmonary hypertension in mice Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments Year: 2012
17(R)-resolvinD1 mediates a pathway involving the transcription factor c-Fos to reduce bleomycin-induced pulmonary fibrosis in mice. Source: International Congress 2018 – Novel insights in the basic and translational research on idiopathic interstitial pneumonias Year: 2018
Sirtuins inhibition modulates endotoxin-induced lung inflammation Source: Annual Congress 2010 - Models of airways disease Year: 2010
Effects of elastase inhibitor on the epithelial cell apoptosis in bleomycin-induced pulmonary fibrosis Source: Annual Congress 2008 - Management of idiopathic pulmonary fibrosis: what can we learn from the pathophysiology? Year: 2008
Prevention of fetal programming of pulmonary vascular dysfunction by a histone deacetylase inhibitor Source: Annual Congress 2010 - Experimental pulmonary hypertension Year: 2010
Overexpression of ISCU can extenuate mitochondrial damage, reduce EMT and bleomycin-induced pulmonary fibrosis Source: Virtual Congress 2020 – Mechanistic insight into lung injury and repair Year: 2020
Cigarette-decreased NAD/SIRT1 aggravates pulmonary fibrosis by promoting senescence of alveolar type 2 cells through autophagy inhibition and mitochondrial oxidative stress induction Source: Virtual Congress 2020 – Idiopathic pulmonary fibrosis and interstitial lung disease: progression, genes and more Year: 2020
Histone deacetylase inhibition significantly augments human mesothelioma cellular response to chemotherapeutic agents Source: Eur Respir J 2001; 18: Suppl. 33, 396s Year: 2001
A T cell-specific inhibitor of NF-kappaB and AP-1 suppresses lung fibrosis in mice Source: Eur Respir J 2004; 24: Suppl. 48, 101s Year: 2004
Disruption of Nrf2 enhances susceptibility to pulmonary fibrosis induced by bleomycin in mice Source: Annual Congress 2011 - The ageing pulmonary interstitium Year: 2011
Involvement of proteasome inhibition and p53 accumulation in epithelial apoptosis of lung injury Source: Eur Respir J 2005; 26: Suppl. 49, 101s Year: 2005
Follistatin-like 1 promotes intermittent hypoxia-induced lung fibroblast activation in vitro and in vivo Source: International Congress 2019 – Immune-mediated interstitial lung diseases: from bench to bedside Year: 2019
Metformin attenuates bleomycin-induced pulmonary fibrosis in mice via IGF-1 suppression Source: International Congress 2018 – Novel insights in the basic and translational research on idiopathic interstitial pneumonias Year: 2018
SIRT1, a histone deacetylase, regulates matrix metalloproteinase-9 expression Source: Annual Congress 2005 - Pulmonary hypertension and fibrosis: novel mechanisms Year: 2005