The search for evidence of the efficacy of augmentation therapy in AATD

R. Sandhaus (Miami, United States of America)

Source: Annual Congress 2013 –Alpha-1 antitrypsin deficiency and the lung: celebrating the 50th anniversary of its first description

Slide presentationMultimedia files

Rating: 5
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
R. Sandhaus (Miami, United States of America). The search for evidence of the efficacy of augmentation therapy in AATD. Annual Congress 2013 –Alpha-1 antitrypsin deficiency and the lung: celebrating the 50th anniversary of its first description

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

Odile Sellier-Kessler - 30.09.2013 17:27
great presentation on such a controversial topic
You must Login to comment this presentation.


Related content which might interest you:
Anti-IgE therapy: rationale and clinical evidence
Source: Annual Congress 2007 - Changing practice with anti-IgE: patient, physician and payor perspectives
Year: 2007

The efficacy and safety of adjunctive corticosteroids in the treatment of tuberculous pleurisyA systematic review and meta-analysis
Source: International Congress 2017 – TB: diagnosis, severity and practical management
Year: 2017

Triple therapy versus single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis
Source: Eur Respir J, 52 (6) 1801586; 10.1183/13993003.01586-2018
Year: 2018



Triple therapy versus dual bronchodilation and long-acting ß-agonists/inhaled corticosteroids in COPD: accumulating evidence from network meta-analyses
Source: International Congress 2019 – Therapeutic breakthrough Year in review
Year: 2019


Does the use of inhaled corticosteroids in asthma benefit lung function in the long-term? A systematic review and meta-analysis
Source: Eur Respir Rev, 30 (159) 200185; 10.1183/16000617.0185-2020
Year: 2021



Lack of clinically relevant differences between combination therapy and monotherapy in COPD
Source: Eur Respir J 2014; 43: 1204
Year: 2014


Lack of clinically relevant differences between combination therapy and monotherapy in COPD
Source: Eur Respir J 2014; 43: 1204-1205
Year: 2014


Evaluation of efficacy and safety of budesonide/formeterol combination therapy in asthma patients
Source: Eur Respir J 2006; 28: Suppl. 50, 314s
Year: 2006

Chinese subgroup results from a study comparing single-inhaler triple therapy with dual therapy in COPD
Source: International Congress 2017 – COPD management
Year: 2017


The efficacy and safety of inhaled antibiotics for the treatment of bronchiectasis in adults: a systematic review and meta-analysis
Source: International Congress 2019 – Clinical and translational studies of bronchiectasis and non-TB mycobacterial infection
Year: 2019

What is the scientific and clinical rationale? Triple therapy in COPD patients
Source: Virtual Congress 2021 – Linking scientific mechanisms to recent clinical therapeutic advances in airway disease: why, who, when and what?
Year: 2021


Antiviral therapy – the evidence base and clinical trials
Source: International Congress 2015 – PG11 Emerging infectious diseases and pandemic planning
Year: 2015



Does azithromycin-prednisolone combination therapy have additive effects than single therapy in patients with persistent asthma?
Source: Annual Congress 2009 - Aspects of uncontrolled asthma
Year: 2009


Clinical effectiveness of triple therapy in the management of COPD: A systematic review
Source: Annual Congress 2010 - Risk factors, prevalence and consequences of COPD
Year: 2010


Inadequate assessment of adherence to maintenance medication leads to loss of power and increased costs in trials of severe asthma therapy: results from a systematic literature review and modelling study
Source: Eur Respir J, 53 (5) 1802161; 10.1183/13993003.02161-2018
Year: 2019



Proof of concept study to evaluate step down therapy with inhaled corticosteroid alone or additive therapy on surrogate inflammatory markers in asthma
Source: Annual Congress 2010 - Pharmacological modulation of biomarkers and management
Year: 2010

The effect of anti-acid therapy on survival in idiopathic pulmonary fibrosis: a methodological review of observational studies
Source: Eur Respir J, 51 (6) 1800376; 10.1183/13993003.00376-2018
Year: 2018



Is there a benefit of an additive standard immunoglobulin therapy for the clinical course of COPD patients under chronic immunosuppressive therapy?
Source: Eur Respir J 2001; 18: Suppl. 33, 24s
Year: 2001

Consequences of long-term oral corticosteroid therapy and its side-effects in severe asthma in adults: a focused review of the impact data in the literature
Source: Eur Respir J, 52 (4) 1800703; 10.1183/13993003.00703-2018
Year: 2018