Intermittent hypoxia-activated cyclooxygenase pathway: role in atherosclerosis

Gautier-Veyret Elodie, Arnaud Claire, Bäck Magnus, Pépin Jean-Louis, Petri Marcelo H., Baguet Jean-Philippe, Tamisier Renaud, Lévy Patrick, Stanke-Labesque Françoise

Source: Eur Respir J 2013; 42: 404-413
Journal Issue: August
Disease area: Sleep and breathing disorders

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Gautier-Veyret Elodie, Arnaud Claire, Bäck Magnus, Pépin Jean-Louis, Petri Marcelo H., Baguet Jean-Philippe, Tamisier Renaud, Lévy Patrick, Stanke-Labesque Françoise. Intermittent hypoxia-activated cyclooxygenase pathway: role in atherosclerosis. Eur Respir J 2013; 42: 404-413

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Role of RhoA/Rho-kinase pathway in the regulation of eNOS activity in COPD patients
Source: Annual Congress 2010 - Pathobiology of pulmonary hypertension
Year: 2010


Attenuated expression and activity of dimethylarginine dimethylaminohydrolase may play a key role in monocrotaline-induced pulmonary hypertension by accumulation of endogenous NOS inhibitors in rats
Source: Annual Congress 2006 - Signalisation in the pulmonary vasculature: new pathways and wrong signals
Year: 2006


Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension
Source: Eur Respir J, 54 (6) 1900378; 10.1183/13993003.00378-2019
Year: 2019



Oral presentation: Genetic or pharmacologic inhibition of ATX stimulates LPS-induced pulmonary inflammation
Source: Lung Science Conference 2010 - Biology of gene-environment interactions in the lung
Year: 2010

The anti-inflammatory effects of sulforaphane are not mediated by the Nrf2 pathway
Source: International Congress 2014 – Novel approaches and evidence for drug development in respiratory diseases
Year: 2014

Effect of cyclooxygenase-2 inhibition on lung inflammation and hypoxia-inducible factor-1 signalling in COPD model
Source: International Congress 2017 – Insight into the pathogenesis of emphysema and pneumonia
Year: 2017


6-aminonicotinamide ameliorates pulmonary fibrosis by suppressing the TGF-beta1 activated Smad signalling pathway
Source: Virtual Congress 2020 – Translational therapeutic advances
Year: 2020


Role of interleukin-1 receptor 1/MyD88 signalling in the development and progression of pulmonary hypertension
Source: Eur Respir J 2016; 48: 470-483
Year: 2016



Oral presentation: Protease-activated receptor-2 plays a pivotal role in pulmonary fibrosis by inducing myofibroblast differentiation and tissue factor up-regulation
Source: Lung Science Conference 2010 - Biology of gene-environment interactions in the lung
Year: 2010

Pharmacological activation of Nur77 enhances BMP signalling and inhibits vascular remodelling in pulmonary arterial hypertension
Source: International Congress 2018 – Pathobiology of pulmonary hypertension
Year: 2018



Dual inhibition of thromboxane synthase and 5-lipoxygenase, potentially significant mechanism for the treatment of asthma
Source: Eur Respir J 2001; 18: Suppl. 33, 264s
Year: 2001

Modulation of oxidative stress pathway by arginase inhibition: Evaluation in an animal model of chronic pulmonary inflammation
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010


TSC1/mTOR pathway promotes hypoxia-induced pulmonary hypertension in mice
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Year: 2012


Effect of endothelin on DNA synthesis in human bronchial eipthelial cells: role of MAPK cascade
Source: Eur Respir J 2001; 18: Suppl. 33, 476s
Year: 2001

Intermittent hypoxia activates the Interleukin (IL)-1ß and nuclear factor (NF)?B signaling pathway in primary murine macrophages
Source: International Congress 2019 – Insights into the pathophysiology of sleep-disordered breathing
Year: 2019



A novel piperidine attenuates pulmonary arterial hypertension via regulating BMP2 and PTGS2 levels
Source: International Congress 2018 – Pathobiology of pulmonary hypertension
Year: 2018



Endothelin-1 contributes to the downregulation of BMP/BMPR2 signaling induced by hypoxia
Source: International Congress 2015 – Pulmonary hypertension: novel insights into the biology of the disease
Year: 2015