Effects of roflumilast on early and late allergic response and airway hyperresponsiveness in Aspergillus fumigatus-sensitized mice

H. G. Hoymann, R. Korolewitz, A. Braun, N. Krug, L. Wollin, R. Beume (Hannover, Konstanz, Germany)

Source: Annual Congress 2005 - New perspectives in asthma treatment
Session: New perspectives in asthma treatment
Session type: Poster Discussion
Number: 1391
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
H. G. Hoymann, R. Korolewitz, A. Braun, N. Krug, L. Wollin, R. Beume (Hannover, Konstanz, Germany). Effects of roflumilast on early and late allergic response and airway hyperresponsiveness in Aspergillus fumigatus-sensitized mice. Eur Respir J 2005; 26: Suppl. 49, 1391

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
IPL576,092 reduces allergen-induced late asthmatic responses, sputum eosinophilia and airway hyperresponsiveness in mild asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 104s
Year: 2003

Effects of active and passive smoking on allergic airway inflammation and airway hyperresponsiveness in mice
Source: Eur Respir J 2002; 20: Suppl. 38, 310s
Year: 2002

Effects of OVA-induced allergic airway inflammation and remodeling in mice in three distinct asthma models
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010


The airway inflammatory response in allergic mice is downregulated by budesonide
Source: Eur Respir J 2001; 18: Suppl. 33, 265s
Year: 2001

The effect of Der f-induced airway inflammation on airway inflammation in a murine model of allergic asthma
Source: Eur Respir J 2004; 24: Suppl. 48, 348s
Year: 2004

Different effects of cox-inhibition on airway inflammation and hyperresponsiveness in mice
Source: Eur Respir J 2007; 30: Suppl. 51, 713s
Year: 2007

Effects of IL-4Rα blockade on lung inflammation and airway hyperresponsiveness using Mu317RAXMu, a murine surrogate for AMG 317, in a treatment model of cockroach allergen-induced asthma in mice
Source: Annual Congress 2008 - Novel mechanisms in the pathogenesis of pulmonary inflammation
Year: 2008

Dissociation of airway inflammation and hyperresponsiveness by cyclooxygenase inhibition in allergen challenged mice
Source: Eur Respir J 2009; 34: 200-208
Year: 2009



A role of fungal extracts on allergic airway inflammation in the ovalbumin-induced asthma model
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010

Budesonide prevents but does not reverse sustained airway hyperresponsiveness in mice
Source: Eur Respir J 2008; 32: 970-978
Year: 2008



Effects of ciclesonide and fluticasone propionate on allergen-induced chronic airway inflammation and bronchial hyperreactivity in sensitized brown-Norway rats
Source: Eur Respir J 2003; 22: Suppl. 45, 280s
Year: 2003

5,6,7-Trihydroxy-4´-methoxy-flavanone from Baccharis retusa (asteraceae) attenuates allergen-induced airway inflammation and hyperresponsiveness in mice
Source: Annual Congress 2010 - Regulation of airway hyperresponsiveness and bronchodilators
Year: 2010

HIF-1α inhibitor, 2ME2, attenuates airway inflammation and hyperresponsiveness in allergic airway disease
Source: Annual Congress 2008 - Novel therapeutic approaches and immunological mechanisms in airway cell pathobiology
Year: 2008


Airway allergy in pregnant mice: reduced Th2 responses but enhanced airway hyperresponsiveness
Source: Eur Respir J 2006; 28: Suppl. 50, 590s
Year: 2006

Inhibition by roflumilast of airway hyperresponsiveness to adenosine and pulmonary inflammation in allergen challenged Brown-Norway rats
Source: Eur Respir J 2001; 18: Suppl. 33, 35s
Year: 2001

Effects of budesonide/formoterol maintenance therapy on airway hyperresponsiveness and inflammation in an allergic rat model
Source: Eur Respir J 2004; 24: Suppl. 48, 351s
Year: 2004

Inhaled doxycycline reduces allergen-induced airway inflammation, hyperresponsiveness and remodelling in mice
Source: Annual Congress 2005 - Inflammation and remodelling in allergy and asthma
Year: 2005


Effect of an inhaled alpha4-antagonist on the allergen-induced late asthmatic response in patients with mild asthma
Source: Eur Respir J 2005; 26: Suppl. 49, 135s
Year: 2005

Effects of salbutamol and enantiomers on allergen-induced asthmatic reactions and airway hyperreactivity
Source: Eur Respir J 2005; 25: 864-872
Year: 2005



The inflammation and the airway hyperresponsiveness in allergic asthma is inhibited by IL-10 dependent mechanism
Source: Annual Congress 2007 - Mouse models of allergic airway inflammation
Year: 2007