GB001 potently inhibits PGD2 metabolite-induced DP2-mediated cell signaling and eosinophil activation Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
Theophylline at the therapeutic concentrations abrogate decreased smad7 expression in cultured smooth muscle cells stimulated with LTD4 and EGF Source: Eur Respir J 2005; 26: Suppl. 49, 25s Year: 2005
Inhibition of chloride channel activity by BMP-2 in lung fibroblasts opposes profibrotic action of endothelin-1 Source: Annual Congress 2010 - Pathobiology of pulmonary hypertension Year: 2010
Mechanisms of acetylcholine-induced release of proinflammatory extracellular vesicles by endothelial cells and inhibitory effects of tiotropium Source: International Congress 2019 – Identification of new targets and therapeutic strategies for lung disease Year: 2019
Selective inhibition of COX-2 by celecoxib exerts negative effects on endothelial progenitor cell proliferation and stimulates apoptosis in vitro Source: Eur Respir J 2005; 26: Suppl. 49, 368s Year: 2005
Anti-inflammatory effect of bosentan on endothelin-1- and TNF-α-induced GMCSF expression in human airways smooth muscle cells – role of MAPkinases ERK-1,-2 Source: Annual Congress 2007 - Inflammatory cell biology Year: 2007
COX-1 driven biosynthesis of PGD2 during activation of human mast cells prevents formation of other prostanoids Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes Year: 2020
Platelet-induced 5-LOX activity is associated with ROS-dependent ASMC proliferation Source: Annual Congress 2007 - Inflammatory cell biology Year: 2007
Synergistic action of formoterol on budesonide-generated decrease of proteoglycan production by activated lung fibroblasts is mediated via β-adrenergic receptor and is dependent on glucocorticoid receptor Source: Eur Respir J 2004; 24: Suppl. 48, 345s Year: 2004
In vitro profibrotic effects of rapamycin on basal or TGF-β1 induced primary human lung fibroblast: ECM production and turnover, migration and differentiation Source: Annual Congress 2012 - Diffuse parenchymal lung disease I Year: 2012
Anti-inflammatory function of tiotropium mediated by suppression of acetylcholine-induced release of chemotactic activity Source: Eur Respir J 2004; 24: Suppl. 48, 318s Year: 2004
Differential role of EPAC and PKA in the transduction of cAMP-mediated inhibition of human lung fibroblast proliferation and collagen synthesis Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation Year: 2009
Inhibition of LPS-induced cytokine/chemokine production from human lung macrophages by roflumilast is enabled by autocrine PGE2 Source: Annual Congress 2010 - Macrophages: cell biology and disease-specific characteristics Year: 2010
Prostaglandin-E2 mediated inhibition of TNFα release from human alveolar macrophages Source: Eur Respir J 2005; 26: Suppl. 49, 223s Year: 2005
Bradykinin-induced fibroblast proliferation and myofibroblast differentiation via B2 receptor pathway Source: Eur Respir J 2005; 26: Suppl. 49, 342s Year: 2005
IL-1β-induced MCP-1 production in human airway smooth muscle cells, modulation by dexamethasone, rolipram, and salbutamol Source: Eur Respir J 2001; 18: Suppl. 33, 353s Year: 2001
N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation Source: Eur Respir J 2002; 20: Suppl. 38, 170s Year: 2002
Effects of glucocorticosteroids and antimicrobial drugs on inhibition of IL-1β- and PDBu-induced IL-8 release in the presence of pyocyanin in bronchial epithelial cell line Source: Eur Respir J 2005; 26: Suppl. 49, 99s Year: 2005
Effects of TGF-beta and budesonide on MAPK phosphorylation, IL-6/IL-11 secretion, and cell proliferation in human lung fibroblasts Source: Eur Respir J 2006; 28: Suppl. 50, 662s Year: 2006
Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 454s Year: 2004