Genetic risk factors for obstructive lung disease and sarcoidosis

Oral Presentation
Chairs: D. S. Postma (Groningen, The Netherlands), F. Kauffmann (Villejuif, France)

Heme oxygenase 1 promoter variants affect FEV₁ decline in the general population M. Siedlinski, D. S. Postma, H. A. Smit, G. van der Steege, M. Bruinenberg, M. Platteel, H. M. Boezen (Groningen, Bilthoven, Netherlands)
GSTT1 null alleles are risk factors for excess FEV₁ decline in the general population, but GSTM1 null alleles only in smokers C. C. van Diemen, D. S. Postma, M. Bruinenberg, H. M. Boezen (Groningen, Netherlands)
*Polymorphisms in de novo* glutathione biosynthesis genes affect lung function in heavy smokers** M. Siedlinski, D. S. Postma, H. A. Smit, C. C. van Diemen, G. van der Steege, E. Oosterom, H. M. Boezen (Groningen, Bilthoven, Netherlands)
Gene polymorphisms in glutathione peroxidase and glutathione-S-transferase affects FEV₁ in smokers T. H. Malling, C. B. Andersen, I. Brandslund, D. Sherson, L. R. Skadhauge, T. Sigsgaard, O. Omland (Aalborg, Odense, Vejle, Haderslev, Århus, Denmark)
A strategy to select COPD cases in case-control studies: the genes–environment interaction on respiratory diseases (GEIRD) project S. Accordini, A. Corsico, I. Cerveri, L. Cazzoletti, M. Ferrari, V. Lo Cascio, A. Marcon, A. Marinoni, M. Olivieri, L. Perbellini, M. Rava, G. Verlato, R. de Marco (Verona, Pavia, Italy)
Glutathione peroxidase, glutathione-S-transferase T1 and M1 polymorphisms are associated to bronchial hyperresponsiveness but not to asthma O. Omland, T. H. Malling, C. B. Andersen, I. Brandslund, D. Sherson, L. R. Skadhauge, T. Sigsgaard (Aalborg, Odense, Vejle, Haderslev, Århus, Denmark)
Replication of positionally cloned asthma genes in an international population-based cohort study (ECRHS-II) M. Kogevinas, F. Castro-Giner, R. de Cid, D. Jarvis, K. van Steen, J. M. Anto, M. Wjst (Barcelona, Spain; London, United Kingdom; Neuherberg, München, Germany)
A registry-based twin study of sarcoidosis epidemiology A. Sverrild, S. F. Thomsen, K. O. Kyvik, N. Milman, C. B. Svendsen, V. Backer (Copenhagen, Odense, Denmark)