June

World Bronchiectasis Day 2022 James D. Chalmers, Timothy Aksamit, Stefano Aliberti, Raja Dhar, Lucy C. Morgan Eur Respir J, 59 (6) 2201249; 10.1183/13993003.01249-2022
Addressing the effect of ancestry on lung volume Brian L. Graham, Martin R. Miller, Bruce R. Thompson Eur Respir J, 59 (6) 2200882; 10.1183/13993003.00882-2022
International consensus statement on quality standards for managing children/adolescents with bronchiectasis from the ERS CRC Child-BEAR-Net Anne B. Chang, Jeanette Boyd, Andrew Bush, Adam T. Hill, Zena Powell, Angela Zacharasiewicz, Efthymia Alexopoulou, James D. Chalmers, Andrew J. Collaro, Carolina Constant, Konstantinos Douros, Rebecca Fortescue, Matthias Griese, Jonathan Grigg, Andreas Hector, Bulent Karadag, Oleksandr Mazulov, Fabio Midulla, Alexander Moeller, Marijke Proesmans, Christine Wilson, Stephanie T. Yerkovich, Ahmad Kantar, Keith Grimwood Eur Respir J, 59 (6) 2200264; 10.1183/13993003.00264-2022
Strokes of a pen: seeing far beyond COVID-19 Massimiliano Polastri, Salvatore Campanello Eur Respir J, 59 (6) 2102264; 10.1183/13993003.02264-2021
Bronchodilators in bronchiectasis: there is light but it is still too dim Mario Cazzola, Miguel Ángel Martínez-García, Maria Gabriella Matera Eur Respir J, 59 (6) 2103127; 10.1183/13993003.03127-2021
To be or not to be… treated with initial combination therapy, that is the (PAH) question Athénaïs Boucly, Marc Humbert, Olivier Sitbon Eur Respir J, 59 (6) 2200390; 10.1183/13993003.00390-2022
ERS statement on paediatric long-term noninvasive respiratory support Brigitte Fauroux, François Abel, Alessandro Amaddeo, Elisabetta Bignamini, Elaine Chan, Linda Corel, Renato Cutrera, Refika Ersu, Sophie Installe, Sonia Khirani, Uros Krivec, Omendra Narayan, Joanna MacLean, Valeria Perez De Sa, Marti Pons-Odena, Florian Stehling, Rosario Trindade Ferreira, Stijn Verhulst Eur Respir J, 59 (6) 2101404; 10.1183/13993003.01404-2021
Lung transplantation for acute respiratory distress syndrome: a retrospective European cohort study Jens Gottlieb, Philipp M. Lepper, Cristina Berastegui, Beatriz Montull, Alexandra Wald, Jasvir Parmar, Jesper M. Magnusson, Felix Schönrath, Tanel Laisaar, Sebastian Michel, Hillevi Larsson, Robin Vos, Assad Haneya, Tim Sandhaus, Erik Verschuuren, Jérôme le Pavec, Jussi Tikkanen, Konrad Hoetzenecker Eur Respir J, 59 (6) 2102078; 10.1183/13993003.02078-2021
Clinical validation of digital biomarkers for paediatric patients with asthma and cystic fibrosis: potential for clinical trials and clinical care Matthijs D. Kruizinga, Esmée Essers, Frederik E. Stuurman, Yalçin Yavuz, Marieke L. de Kam, Ahnjili Zhuparris, Hettie M. Janssens, Iris Groothuis, Arwen J. Sprij, Marianne Nuijsink, Adam F. Cohen, Gertjan J.A. Driessen Eur Respir J, 59 (6) 2100208; 10.1183/13993003.00208-2021
Using chest computed tomography and unsupervised machine learning for predicting and evaluating response to lumacaftor–ivacaftor in people with cystic fibrosis Alienor Campredon, Enzo Battistella, Clémence Martin, Isabelle Durieu, Laurent Mely, Christophe Marguet, Chantal Belleguic, Marlène Murris-Espin, Raphaël Chiron, Annlyse Fanton, Stéphanie Bui, Martine Reynaud-Gaubert, Philippe Reix, Trieu-Nghi Hoang-Thi, Maria Vakalopoulou, Marie-Pierre Revel, Jennifer Da Silva, Pierre-Régis Burgel, Guillaume Chassagnon, Julie Mounard, Claire Poulet, Cinthia Rames (Amiens), Christine Person, Françoise Troussier, Thierry Urban (Angers), Marie-Laure Dalphin, Jean-Claude Dalphin, Didier Pernet, Bénédicte Richaud-Thiriez (Besançon), Stéphanie Bui, Mickael Fayon, Julie Macey-Caro (Bordeaux), Karine Campbell, Muriel Laurans (Caen), Corinne Borderon, Marie-Christine Heraud, André Labbé, Sylvie Montcouquiol (Clermont-Ferrand), Laurence Bassinet, Natascha Remus (Créteil), Annlyse Fanton, Anne Houzel-Charavel, Frédéric Huet, Stéphanie Perez-Martin (Dijon), Amale Boldron-Ghaddar, Manuela Scalbert (Dunkerque), Laurent Mely (Giens), Boubou Camara, Catherine Llerena, Isabelle Pin, Sébastien Quétant (Grenoble), Aurélie Cottereau, Antoine Deschildre, Alice Gicquello, Thierry Perez, Lidwine Stervinou-Wemeau, Caroline Thumerelle, Benoit Wallaert, Nathalie Wizla (Lille), Jane Languepin, Céline Ménétrey, Magalie Dupuy-Grasset (Limoges), Lucie Bazus, Clelia Buchs, Virginie Jubin, Marie-Christine Werck-Gallois, Catherine Mainguy, Thomas Perrin, Philippe Reix, Agnès Toutain-Rigolet (Lyon Pédiatrie), Isabelle Durieu, Stéphane Durupt, Quitterie Reynaud, Raphaele Nove-Josserand (Lyon adultes), Melisande Baravalle-Einaudi, Bérangère Coltey, Nadine Dufeu, Jean-Christophe Dubus, Nathalie Stremler (Marseille), Davide Caimmi, Raphaël Chiron (Montpellier), Yves Billon, Jocelyne Derelle, Sébastien Kieffer, Anne-Sophie Pichon, Cyril Schweitzer, Aurélie Tatopoulos (Nancy), Sarah Abbes, Tiphaine Bihouée, Isabelle Danner-Boucher, Valérie David, Alain Haloun, Adrien Tissot (Nantes), Sylvie Leroy, Carole Bailly-Piccini (Nice), Annick Clément, Harriet Corvol, Aline Tamalet (ParisTrousseau), Pierre-Régis Burgel, Isabelle Honoré, Dominique Hubert, Reem Kanaan, Clémence Martin (Paris Cochin), Cécile Bailly, Frédérique Chédevergne, Jacques De Blic, Brigitte Fauroux, Murielle Le Bourgeois, Isabelle Sermet-Gaudelus (Paris Necker), Bertrand Delaisi, Michèle Gérardin, Anne Munck (ParisRobert Debré), Michel Abély, Bruno Ravoninjatovo (Reims), Chantal Belleguic, Benoit Desrues, Graziella Brinchault (Rennes), Michel Dagorne, Eric Deneuville, Sylvaine Lefeuvre (Rennes-Saint Brieuc), Anne Dirou, Jean Le Bihan, Sophie Ramel (Roscoff), Stéphane Dominique, Christophe Marguet (Rouen), Annabelle Payet (La Réunion), Romain Kessler, Michele Porzio, Vincent Rosner, Laurence Weiss (Strasbourg), Sandra de Miranda, Dominique Grenet, Abdoul Hamid, Clément Picard (Suresnes), François Brémont, Alain Didier, Géraldine Labouret, Marie Mittaine, Marlène Murris-Espin, Laurent Têtu (Toulouse), Laure Cosson, Charlotte Giraut, Anne-Cécile Henriet, Julie Mankikian, Sophie Marchand (Tours), Sandrine Hugé, Véronique Storni (Vannes), Emmanuelle Coirier-Duet (Versailles) Eur Respir J, 59 (6) 2101344; 10.1183/13993003.01344-2021
Tiotropium treatment for bronchiectasis: a randomised, placebo-controlled, crossover trial Lata Jayaram, Alain C. Vandal, Catherina L. Chang, Chris Lewis, Cecilia Tong, Christine Tuffery, Jill Bell, Wendy Fergusson, Gene Jeon, David Milne, Stuart Jones, Noel Karalus, Sandra Hotu, Conroy Wong Eur Respir J, 59 (6) 2102184; 10.1183/13993003.02184-2021
Randomised trial of the P2X₃ receptor antagonist sivopixant for refractory chronic cough Akio Niimi, Junpei Saito, Tadashi Kamei, Masaharu Shinkai, Hiroyuki Ishihara, Mitsuaki Machida, Sayaka Miyazaki Eur Respir J, 59 (6) 2100725; 10.1183/13993003.00725-2021
External validation of a refined four-stratum risk assessment score from the French pulmonary hypertension registry Athénaïs Boucly, Jason Weatherald, Laurent Savale, Pascal de Groote, Vincent Cottin, Grégoire Prévot, Ari Chaouat, François Picard, Delphine Horeau-Langlard, Arnaud Bourdin, Etienne-Marie Jutant, Antoine Beurnier, Mitja Jevnikar, Xavier Jaïs, Gérald Simonneau, David Montani, Olivier Sitbon, Marc Humbert Eur Respir J, 59 (6) 2102419; 10.1183/13993003.02419-2021
Right atrial function is associated with right venticular diastolic stiffness: RA–RV interaction in pulmonary arterial hypertension Jeroen N. Wessels, Sophia A. Mouratoglou, Jessie van Wezenbeek, M. Louis Handoko, J. Tim Marcus, Lilian J. Meijboom, Berend E. Westerhof, Harm Jan Bogaard, Gustav J. Strijkers, Anton Vonk Noordegraaf, Frances S. de Man Eur Respir J, 59 (6) 2101454; 10.1183/13993003.01454-2021
Temporal trends in pulmonary arterial hypertension: results from the COMPERA registry Marius M. Hoeper, Christine Pausch, Ekkehard Grünig, Gerd Staehler, Doerte Huscher, David Pittrow, Karen M. Olsson, Carmine Dario Vizza, Henning Gall, Oliver Distler, Christian Opitz, J. Simon R. Gibbs, Marion Delcroix, H. Ardeschir Ghofrani, Stephan Rosenkranz, Da-Hee Park, Ralf Ewert, Harald Kaemmerer, Tobias J. Lange, Hans-Joachim Kabitz, Dirk Skowasch, Andris Skride, Martin Claussen, Juergen Behr, Katrin Milger, Michael Halank, Heinrike Wilkens, Hans-Jürgen Seyfarth, Matthias Held, Daniel Dumitrescu, Iraklis Tsangaris, Anton Vonk-Noordegraaf, Silvia Ulrich, Hans Klose Eur Respir J, 59 (6) 2102024; 10.1183/13993003.02024-2021
Mortality trends in pulmonary arterial hypertension in Canada: a temporal analysis of survival per ESC/ERS guideline era Jason G.E. Zelt, Jordan Sugarman, Jason Weatherald, Arun C.R. Partridge, Jiaming (Calvin) Liang, John Swiston, Nathan Brunner, George Chandy, Duncan J. Stewart, Vladimir Contreras-Dominguez, Mitesh Thakrar, Doug Helmersen, Rhea Varughese, Naushad Hirani, Fraz Umar, Rosemary Dunne, Caroyln Doyle-Cox, Julia Foxall, Lisa Mielniczuk Eur Respir J, 59 (6) 2101552; 10.1183/13993003.01552-2021
Lung function trajectory in progressive fibrosing interstitial lung disease Justin M. Oldham, Cathryn T. Lee, Zhe Wu, Willis S. Bowman, Janelle Vu Pugashetti, Nam Dao, James Tonkin, Hasan Seede, Gabrielle Echt, Ayodeji Adegunsoye, Felix Chua, Toby M. Maher, Christine K. Garcia, Mary E. Strek, Chad A. Newton, Philip L. Molyneaux Eur Respir J, 59 (6) 2101396; 10.1183/13993003.01396-2021
The psychometric properties of the King's Brief Interstitial Lung Disease questionnaire and thresholds for meaningful treatment response in patients with progressive fibrosing interstitial lung diseases Surinder S. Birring, Donald M. Bushnell, Michael Baldwin, Heiko Mueller, Natalia Male, Klaus B. Rohr, Yoshikazu Inoue Eur Respir J, 59 (6) 2101790; 10.1183/13993003.01790-2021
Nebulised liposomal amphotericin-B as maintenance therapy in allergic bronchopulmonary aspergillosis: a randomised, multicentre trial Cendrine Godet, Francis Couturaud, Sylvain Marchand-Adam, Christophe Pison, Frédéric Gagnadoux, Elodie Blanchard, Camille Taillé, Bruno Philippe, Sandrine Hirschi, Claire Andréjak, Arnaud Bourdin, Cécile Chenivesse, Stéphane Dominique, Laurence Bassinet, Marlène Murris-Espin, Frédéric Rivière, Gilles Garcia, Denis Caillaud, François-Xavier Blanc, François Goupil, Anne Bergeron, Anne Gondouin, Jean-Pierre Frat, Thomas Flament, Boubou Camara, Pascaline Priou, Anne-Laure Brun, François Laurent, Stéphanie Ragot, Jacques Cadranel Eur Respir J, 59 (6) 2102218; 10.1183/13993003.02218-2021
Neonatal metabolome of caesarean section and risk of childhood asthma Gözde Gürdeniz, Madeleine Ernst, Daniela Rago, Min Kim, Julie Courraud, Jakob Stokholm, Klaus Bønnelykke, Anders Björkbom, Urvish Trivedi, Søren J. Sørensen, Susanne Brix, David Hougaard, Morten Rasmussen, Arieh S. Cohen, Hans Bisgaard, Bo Chawes Eur Respir J, 59 (6) 2102406; 10.1183/13993003.02406-2021
Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study Stacey N. Reinke, Shama Naz, Romanas Chaleckis, Hector Gallart-Ayala, Johan Kolmert, Nazanin Z. Kermani, Angelica Tiotiu, David I. Broadhurst, Anders Lundqvist, Henric Olsson, Marika Ström, Åsa M. Wheelock, Cristina Gómez, Magnus Ericsson, Ana R. Sousa, John H. Riley, Stewart Bates, James Scholfield, Matthew Loza, Frédéric Baribaud, Per S. Bakke, Massimo Caruso, Pascal Chanez, Stephen J. Fowler, Thomas Geiser, Peter Howarth, Ildikó Horváth, Norbert Krug, Paolo Montuschi, Annelie Behndig, Florian Singer, Jacek Musial, Dominick E. Shaw, Barbro Dahlén, Sile Hu, Jessica Lasky-Su, Peter J. Sterk, Kian Fan Chung, Ratko Djukanovic, Sven-Erik Dahlén, Ian M. Adcock, Craig E. Wheelock Eur Respir J, 59 (6) 2101733; 10.1183/13993003.01733-2021
Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures Arutha Kulasinghe, Chin Wee Tan, Anna Flavia Ribeiro dos Santos Miggiolaro, James Monkman, Habib SadeghiRad, Dharmesh D. Bhuva, Jarbas da Silva Motta Junior, Caroline Busatta Vaz de Paula, Seigo Nagashima, Cristina Pellegrino Baena, Paulo Souza-Fonseca-Guimaraes, Lucia de Noronha, Timothy McCulloch, Gustavo Rodrigues Rossi, Caroline Cooper, Benjamin Tang, Kirsty R. Short, Melissa J. Davis, Fernando Souza-Fonseca-Guimaraes, Gabrielle T. Belz, Ken O'Byrne Eur Respir J, 59 (6) 2101881; 10.1183/13993003.01881-2021
The physiological basis of pulmonary arterial hypertension Robert Naeije, Manuel J. Richter, Lewis J. Rubin Eur Respir J, 59 (6) 2102334; 10.1183/13993003.02334-2021
Childhood asthma: pathogenesis and phenotypes Mariëlle W. Pijnenburg, Urs Frey, Johan C. De Jongste, Sejal Saglani Eur Respir J, 59 (6) 2100731; 10.1183/13993003.00731-2021
Novel avenues to approach non-CPAP therapy and implement comprehensive obstructive sleep apnoea care Jean-Louis Pépin, Peter Eastwood, Danny J. Eckert Eur Respir J, 59 (6) 2101788; 10.1183/13993003.01788-2021
Erythrocytes are altered in pulmonary arterial hypertension Etienne-Marie Jutant, Ly Tu, Raphaël Thuillet, Véronique Picard, Christophe Guignabert, Florence Parent, Olivier Sitbon, Marc Humbert, Laurent Savale, Alice Huertas Eur Respir J, 59 (6) 2200506; 10.1183/13993003.00506-2022
Dupilumab efficacy and safety in patients with asthma and blood eosinophils =500 cells·µL^-1 Klaus F. Rabe, Ian D. Pavord, Mario Castro, Michael E. Wechsler, Nadia Daizadeh, Upender Kapoor, Benjamin Ortiz, Amr Radwan, Robert R. Johnson, Paul J. Rowe, Yamo Deniz, Juby A. Jacob-Nara Eur Respir J, 59 (6) 2102577; 10.1183/13993003.02577-2021
Nontuberculous mycobacterial pulmonary disease incidence among elderly patients with bronchiectasis Kimberly Schildknecht, Kevin L. Winthrop, D. Rebecca Prevots, Rebekah Blakney, Emily Henkle Eur Respir J, 59 (6) 2200018; 10.1183/13993003.00018-2022
Single-cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis Katharina Heinzelmann, Qianjiang Hu, Yan Hu, Evgenia Dobrinskikh, Meshal Ansari, M. Camila Melo-Narváez, Henrik M. Ulke, Colton Leavitt, Carol Mirita, Tammy Trudeau, Maxwell L. Saal, Pamela Rice, Bifeng Gao, William J. Janssen, Ivana V. Yang, Herbert B. Schiller, Eszter K. Vladar, Mareike Lehmann, Melanie Königshoff Eur Respir J, 59 (6) 2102373; 10.1183/13993003.02373-2021
Treatment outcome definitions in chronic pulmonary aspergillosis: a CPAnet consensus statement Eva Van Braeckel, Iain Page, Jesper Rømhild Davidsen, Christian B. Laursen, Ritesh Agarwal, Ana Alastruey-Izquierdo, Aleksandra Barac, Jacques Cadranel, Arunaloke Chakrabarti, Oliver A. Cornely, David W. Denning, Holger Flick, Jean-Pierre Gangneux, Cendrine Godet, Yuta Hayashi, Christophe Hennequin, Martin Hoenigl, Muhammed Irfan, Koichi Izumikawa, Won-Jun Koh, Chris Kosmidis, Christoph Lange, Bernd Lamprecht, Francois Laurent, Oxana Munteanu, Rita Oladele, Thomas F. Patterson, Akira Watanabe, Helmut J.F. Salzer Eur Respir J, 59 (6) 2102950; 10.1183/13993003.02950-2021
Shunt-type plexiform lesions identified in the Sugen5416/hypoxia rat model of pulmonary arterial hypertension using synchrotron-based phase-contrast micro-CT Oscar van der Have, Christian Westöö, Filip Ahrné, Xuefei Tian, Kenzo Ichimura, Till Dreier, Christian Norvik, Maya E. Kumar, Edda Spiekerkoetter, Karin Tran-Lundmark Eur Respir J, 59 (6) 2102802; 10.1183/13993003.02802-2021
Oscillatory mechanics at 36 weeks post-menstrual age as markers of lung disease in preterm infants: a cohort study Emanuela Zannin, Camilla Rigotti, Roland P. Neumann, Raffaele L. Dellacà, Sven Schulzke, Maria Luisa Ventura Eur Respir J, 59 (6) 2103023; 10.1183/13993003.03023-2021
Fraction of exhaled nitric oxide is associated with disease burden in the German Asthma Net severe asthma cohort Christina Bal, Marco Idzko, Sabina Škrgat, Andrea Koch, Katrin Milger, Christian Schulz, Sonja Zehetmayer, Eckard Hamelmann, Roland Buhl, Stephanie Korn Eur Respir J, 59 (6) 2101233; 10.1183/13993003.01233-2021
The curious incident of long COVID symptoms, from an imaginary condition to a recognised syndrome: a “small victory” Valentina E. Di Mattei, Gaia Perego, Francesca Milano, Thomas Eric Hill, Sergio Alfonso Harari Eur Respir J, 59 (6) 2200653; 10.1183/13993003.00653-2022
Inaccuracy of pulse oximetry in darker-skinned patients is unchanged across 32 years Martin J. Tobin, Amal Jubran Eur Respir J, 59 (6) 2200520; 10.1183/13993003.00520-2022
Reply to: Inaccuracy of pulse oximetry in darker-skinned patients is unchanged across 32 years Colin Crooks, Joe West, Tim Card, Dominick Shaw, Mark Simmonds, Andrew Fogarty Eur Respir J, 59 (6) 2200766; 10.1183/13993003.00766-2022
The potential and challenges of radiomics in uncovering prognostic and molecular differences in interstitial lung disease associated with systemic sclerosis Lu Zhang, Jieling Zheng, Zhe Jin, Qiuying Chen, Shuyi Liu, Bin Zhang Eur Respir J, 59 (6) 2102792; 10.1183/13993003.02792-2021
Reply to: The potential and challenges of radiomics in uncovering prognostic and molecular differences in interstitial lung disease associated with systemic sclerosis Janine Schniering, Malgorzata Maciukiewicz, Stephanie Tanadini-Lang, Britta Maurer Eur Respir J, 59 (6) 2200303; 10.1183/13993003.00303-2022
Cause or consequence? Fernando Madalena Volpe Eur Respir J, 59 (6) 2103107; 10.1183/13993003.03107-2021
Reply to: Cause or consequence? Eric D. Bateman, David B. Price, Hao-Chien Wang, Patricia Schonffeldt, Angelina Catanzariti, Ralf J.P. van der Valk, Maarten J.H.I. Beekman Eur Respir J, 59 (6) 2200103; 10.1183/13993003.00103-2022
The efficacy of singing versus exercise training: do the data really support the authors’ conclusions? Anouk W. Vaes, Martijn A. Spruit, Frits M.E. Franssen, Alex J. van ’t Hul, Chris Burtin, Rainer Gloeckl, Sarah Houben-Wilke Eur Respir J, 59 (6) 2102857; 10.1183/13993003.02857-2021
Reply: The effectiveness of singing versus exercise training Anders Løkke, Mette Kaasgaard, Karen Hjerrild Andreasson, Daniel Bech Rasmussen, Ole Hilberg, Peter Vuust, Uffe Bodtger Eur Respir J, 59 (6) 2103051; 10.1183/13993003.03051-2021
Karaoke as a feasible alternative therapy to pulmonary rehabilitation for COPD Mizuki Yuge, Shinsuke Hori, Kenta Ushida, Ryo Momosaki Eur Respir J, 59 (6) 2103113; 10.1183/13993003.03113-2021
“International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma.” Kian Fan Chung, Sally E. Wenzel, Jan L. Brozek, et al. Eur Respir J 2014; 43: 343–373. Eur Respir J, 59 (6) 1362020; 10.1183/13993003.62020-2013