A. Boots (Maastricht, Netherlands), S. Rolandsson Enes (Lund, Sweden)
This session is built from abstracts published on the ERS Congress platform from 23 August, in a PowerPoint format with a pre-recorded audio narration. The live session is scheduled from September 5-7 and each presenter will have a 5-minutes live, slide show presentation followed at the end of the session by 30-minutes general discussion.
This session includes the Best Abstract for Assembly 3 - Basic and translational sciences, entitled "A comprehensive guide to pulmonary mesenchymal populations in the healthy and IPF lung”
LSC - 2021 - A comprehensive guide to pulmonary mesenchymal populations in the healthy and IPF lung.
C. Rowan Simon, X. Liu (xue.liu@cshs.org / Cedars-Sinai Medical Centre,Los Angeles), Y. Wang (yizhou.wang@cshs.org / Cedars-Sinai Medical Centre,Los Angeles), P. W. Noble (paul.noble@cshs.org / Cedars-Sinai Medical Centre,Los Angeles), D. Jiang (dianhua.jiang@cshs.org / Cedars-Sinai Medical Centre,Los Angeles)
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Comparison between Bronchoalveolar Lavage (BAL) and blood-derived microvesicles in lung diseases
E. Bazzan (Padova (PD), Italy), M. Tinè (Padova (PD), Italy), C. Radu (Padova (PD), Italy), D. Biondini (Padova (PD), Italy), M. Damin (Padova (PD), Italy), U. Semenzato (Padova (PD), Italy), A. Casara (Padova (PD), Italy), P. Simioni (Padova (PD), Italy), M. Cosio (Montreal , Canada), M. Saetta (Padova (PD), Italy)
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MSC extracellular vesicles modulate human macrophages in ARDS towards anti-inflammatory phenotype via transfer of miRNA181-a and PTEN-pSTAT5-SOCS1 signalling
Y. Su (Belfast (Northern Ireland), United Kingdom), D. Simpson (Belfast (Northern Ireland), United Kingdom), C. O'Kane (Belfast (Northern Ireland), United Kingdom), D. Brazil (Belfast (Northern Ireland), United Kingdom), A. Krasnodembskaya (Belfast (Northern Ireland), United Kingdom)
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Extracellular vesicles produced by airway epithelial cells in response to oxidative stress contain microRNAs associated with cellular senescence
J. Devulder (London, United Kingdom), J. Baker (London, United Kingdom), L. Donnelly (London, United Kingdom), P. Barnes (London, United Kingdom)
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The NLRP3-inflammasome-caspase-1 pathway is upregulated in idiopathic pulmonary fibrosis and acute exacerbations and is inducible by apoptotic A549 cells
B. Seeliger (Hannover, Germany), B. Jäger (Hannover, Germany), O. Terwolbeck (Hannover, Germany), T. Welte (Hannover, Germany), C. Bode (Bonn, Germany), A. Prasse (Hannover, Germany)
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LSC - 2021 - SRC family kinases modulate molecular pathways associated with mitochondrial dysfunction in idiopathic pulmonary fibrosis
V. Carmen, N. Kahn (nicolas.kahn@web.de / Translational Research Unit, T. ,Heidelberg), M. Hristova (milena_big@yahoo.com / University of Vermont,Burlington), C. M. Dustin (Christopher.Dustin@uvm.edu / University of Vermont,Burlington), M. Kreuter (kreuter@uni-heidelberg.de / Translational Research Unit, T. ,Heidelberg), M. A Schneider (Marc.Schneider@med.uni-heidelberg.de / Translational Research Unit, T. ,Heidelberg), F. Van Schooten (f.vanschooten@maastrichtuniversity.nl / Maastricht University,Maastricht), A. Van Der Vliet (albert.van-der-vliet@med.uvm.edu / University of Vermont,Burlington), A. Boots (a.boots@maastrichtuniversity.nl / Maastricht University,Maastricht)
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Chronic WNT/ß-catenin signaling impairs mitochondrial function in lung epithelial cells
Q. Hu (München, Germany), M. Ansari (München, Germany), I. Angelidis (München, Germany), F. Theis (München, Germany), H. Schiller (München, Germany), M. Königshoff (Pittsburgh, United States of America), M. Lehmann (München, Germany)
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D-dopachrome tautomerase contributes to lung epithelial repair via ACKR3-dependent Akt signaling
S. Song (Groningen, Netherlands), B. Liu (Groningue (GR), Netherlands), H. Habibie (Groningue (GR), Netherlands), . Van Den Bor (Amsterdam, Netherlands), M. Smit (Amsterdam, Netherlands), R. Gosens (Groningen, Netherlands), X. Wu (Groningen, Netherlands), C. Brandsma (Groningen, Netherlands), R. Cool (Groningen, Netherlands), H. Haisma (Groningen, Netherlands), G. Poelarends (Groningen, Netherlands), B. Melgert (Groningen, Netherlands)
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Mast Cell Tryptase Enhances Wound-Healing via Protease-Activated Receptor-2 Dependent Migration in Human Bronchial Epithelial Cells
S. Mogren (Lund, Sweden), F. Berlin (Lund, Sweden), S. Ramu (Lund, Sweden), A. Sverrild (Copenhagen, Denmark), C. Porsbjerg (Copenhagen, Denmark), L. Uller (Lund, Sweden), C. Andersson (Lund, Sweden)
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Late Breaking Abstract - The inflammasome cluster is linked with airway NETosis in COPD
M. Ingelsten (Gothenburg, Sweden), H. Sharifian (Gothenburg, Sweden), M. Rhedin (Gothenburg, Sweden), J. Jirholt (Gothenburg, Sweden), S. Lundin (Gothenburg, Sweden), L. Odqvist (Gothenburg, Sweden), S. Winslow (Gothenburg, Sweden), A. Higham (Manchester, United Kingdom), T. Southworth (Manchester, United Kingdom), D. Singh (Manchester, United Kingdom), A. Berton (Gothenburg, Sweden), Z. Jevnikar (Gothenburg, Sweden)
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Discussion
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