Pathogenic progress in airway diseases

E-poster
Chairs: S. Cuevas Ocaña (Nottingham, United Kingdom), A. Mailleux (Paris, France)
Aims: This session is built from abstracts published on the ERS Congress platform from 23 August, in an e-poster pdf format with a 3-minute audio narration. Participants and chairs of the session are invited to access all e-posters from 23 August to 4 September prior to the 1-hour live, online discussion scheduled from September 5-7. Please note that during live discussion there will be NO e-poster/abstract presentations, only discussion.

Epithelial mesenchymal transition (EMT) related changes in small airways of smokers and patients with COPD W. Lu (Launceston, Australia), J. Markos (Launceston, Australia), C. Chia (Launceston, Australia), J. Larby (Launceston, Australia), G. Haug (Launceston, Australia), A. Hardikar (Hobart, Australia), G. Singhera (Vancouver, Canada), T. Hackett (Vancouver, Canada), M. Eapen (Launceston, Australia), S. Sohal (Launceston, Australia)
The strategy for searching of potential ligands for TRPM8 based on use of Deep Neural Networks and Intermolecular Docking E. Borodin (Blagoveshchensk , Russian Federation), N. Leusova (Blagoveshchensk , Russian Federation), A. Chupalov (Moscow, Russian Federation), P. Timkin (Blagoveshchensk , Russian Federation), E. Timofeev (Blagoveshchensk , Russian Federation), V. Kolosov (Blagoveshchensk , Russian Federation), J. Perelman (Blagoveshchensk , Russian Federation)
Gene expression and genetic variations of HSP70TLR2 and TLR4 in COPD I. Hlapcic (Zagreb, Croatia), M. Grdic Rajkovic (Zagreb, Croatia), A. Hulina-Tomaškovic (Zagreb, Croatia), S. Popovic-Grle (Zagreb, Croatia), M. Radic Antolic (Zagreb, Croatia), L. Rumora (Zagreb, Croatia)
Epigenome-wide DNA methylation profile analysis identifies ABLIM3, ADAM19 and PRICKLE2 associated with COPD J. Hou (Yinchuan, China), X. Wang (Yinchuan, China), Z. Zhao (Yinchuan, China)
Accelerated aging biomarkers in young, old, mild and severe COPD S. Casas Recasens (Barcelona, Spain), B. Garcia Cosio (Palma de Mallorca, Spain), S. Pascual-Guardia (Barcelona, Spain), A. Acosta-Castro (Madrid, Spain), A. Borras-Santos (Barcelona, Spain), J. Gea (Barcelona, Spain), A. Agustí (Barcelona, Spain), R. Faner, Early Study Group (Barcelona, Spain)
Inherited thrombophilia in the development of thrombotic conditions in patients with COPD E. Abduganieva (Tashkent, Uzbekistan), I. Liverko (Tashkent, Uzbekistan), K. Boboev (Tashkent, Uzbekistan), S. Ahmedov (Tashkent, Uzbekistan)
Fatty Acid Desaturases Activity In Patients With Mild And Moderate Asthma Y. Denisenko (Vladivostok, Russian Federation), T. Novgorodtseva (Vladivostok, Russian Federation), M. Antonuyk (Vladivostok, Russian Federation), T. Gvozdenko (Vladivostok, Russian Federation)
Epigenome-wide association study of bronchodilator response in African Americans J. Perez-Garcia (Tenerife, Spain), A. Li (California, United States of America), E. Herrera-Luis (Tenerife, Spain), A. Mak (California, United States of America), L. Borrel (NY, United States of America), D. Hu (California, United States of America), C. Eng (California, United States of America), K. Beckman (MN 55455, United States of America), K. Keys (CA, United States of America), S. Huntsman (California, United States of America), F. Lorenzo-Diaz (Tenerife, Spain), M. Pino-Yanes (Madrid, Spain), E. Burchard (California, United States of America)
Hypoxia-Inducible Factor-1a State in COPD modelingby the method of chronic smoking. N. Zakharchuk (Vladivostok (Primorsky Krai), Russian Federation), V. Nevzorova (Vladivostok (Primorsky Krai), Russian Federation), V. Chertok (Vladivostok (Primorsky Krai), Russian Federation), T. Khairzamanova (Vladivostok (Primorsky Krai), Russian Federation)
AQP5 polymorphism affects dynamics of lung function and asthma control in seasons with contrasting air humidity E. Afanaseva (Blagoveshchensk (Amur Oblast), Russian Federation), D. Naumov (Blagoveshchensk (Amur Oblast), Russian Federation), O. Kotova (Blagoveshchensk (Amur Oblast), Russian Federation), D. Gassan (Blagoveshchensk (Amur Oblast), Russian Federation), E. Sheludko (Blagoveshchensk (Amur Oblast), Russian Federation), I. Sugaylo (Blagoveshchensk (Amur Oblast), Russian Federation), Y. Gorchakova (Blagoveshchensk (Amur Oblast), Russian Federation), V. Kolosov (Blagoveshchensk (Amur Oblast), Russian Federation)
Intermittent hypoxia up-regulates Renin and Cd38 mRNAs in renin-producing cells via miR-203 Y. Takeda (Kashihara, Japan), A. Itaya-Hironaka (Kashihara, Japan), A. Yamauchi (Kashihara, Japan), M. Makino (Kashihara, Japan), S. Sakuramoto-Tsuchida (Kashihara, Japan), H. Ota (Kashihara, Japan), R. Kawaguchi (Kashihara, Japan), S. Takasawa (Kashihara, Japan)
Electronic cigarette aerosol condensate is cytotoxic and increases ACE2 expression in human airway epithelial cells: implications for COVID-19 K. McAlinden (Launceston, Australia), W. Lu (Launceston, Australia), P. Vahidi Ferdowsi (Launceston, Australia), S. Myers (Launceston, Australia), J. Markos (Launceston, Australia), C. Chia (Launceston, Australia), H. Weber (Burnie, Australia), G. Haug (Launceston, Australia), M. Eapen (Launceston, Australia), S. Singh Sohal (Launceston, Australia)
A novel mechanism of autotaxin-mediated cell signaling that is independent of catalytic activity and inhibited by ziritaxestat F. Salgado-Polo (Amsterdam, Netherlands), R. Borza (Amsterdam, Netherlands), P. Ford (Mechelen, Belgium), B. Heckmann (Romainville, France), A. Perrakis (Amsterdam, Netherlands)
Hypoxia induces proinflammatory cytokines production in alpha-1 antitrypsin deficiency patients M. Magallón Serrano (Valencia, Spain), S. Castillo (Valencia, Spain), D. Pellicer (Valencia, Spain), L. Bañuls (Valencia, Spain), S. Bondia (Valencia, Spain), M. Navarro-García (Valencia, Spain), C. González (Valencia, Spain), F. Dasí (Valencia, Spain)
Identification of HuR-specific RNA interactome in TGF-ß1-activated fibroblasts in response to cigarette smoke S. Winslow (Gothenburg, Sweden), L. Griffith (London, United Kingdom), H. Olsson (Gothenburg, Sweden), J. Ule (London, United Kingdom), Z. Jevnikar Rojnik (Gothenburg, Sweden)
Transcriptome analysis of ciliary differentiation in airway epithelium J. Legebeke (Southampton, United Kingdom), K. Horton (Southampton, United Kingdom), G. Wheway (Southampton, United Kingdom), H. Wai (Southampton, United Kingdom), C. Jackson (Southampton, United Kingdom), J. Coles (Southampton, United Kingdom), J. Holloway (Southampton, United Kingdom), J. Lucas (Southampton, United Kingdom), D. Baralle (Southampton, United Kingdom)
Accelerated age-dependent elastin degradation in bronchiectasis J. Huang (Dundee (Angus), United Kingdom), E. Kuzmanova (Dundee (Angus), United Kingdom), W. Macnee (Edinburgh, United Kingdom), B. Miller (Miami, United States of America), R. Tal-Singer (Miami, United States of America), J. Chalmers (Dundee (Angus), United Kingdom)
External quality assessment (EQA) for laboratory diagnosis of alpha1-antitrypsin deficiency (AATD) – Program driven by the European Alpha-1-Research Collaboration (EARCO) network I. Ferrarotti (Pavia , Italy), I. Belmonte (Barcelona, Spain), M. Balduyck (Lille, France), T. Carroll (Dublin, Ireland), A. Corsico (Pavia, Italy), T. Greulich (Marburg, Germany), N. Mcelvaney (Dublin, Ireland), M. Miravitlles (Barcelona, Italy), M. Odou (Lille, France), S. Ottaviani (Pavia, Italy), F. Rodríguez-Frías (Barcelona, Spain), A. Rozy (Warsaw, Poland), S. Seixas (Porto, Portugal), M. Veith (Marburg, Germany), F. Zerimech (Lille, France), J. Chorostowska-Wynimko (Warsaw, Italy)
Adhesion ratio of blood neutrophils from PiZZ COPD patients prior to and during augmentation treatment with alpha-1-antitrypsin U. Lechowicz (Warsaw, Poland), S. Rudzinski (Warsaw, Poland), A. Rozy (Warsaw, Poland), J. Chorostowska-Wynimko (Warsaw, Poland), S. Janciauskiene (Hannover, Germany)