N. Morrell (Cambridge (Cambridgeshire), United Kingdom), L. Dewachter (Bruxelles, Belgium)
This session is built from abstracts published on the ERS Congress platform from 23 August, in an e-poster pdf format with a 3-minute audio narration. Participants and chairs of the session are invited to access all e-posters from 23 August to 4 September prior to the 1-hour live, online discussion scheduled from September 5-7. Please note that during live discussion there will be NO e-poster/abstract presentations, only discussion.
Role of Connexin 43 increased expression in pulmonary arterial hyperreactivityinduced by the nerve growth factor NGF
g. Cardouat (Bordeaux, France), M. Douard (Bordeaux, France), L. Roubenne (Bordeaux, France), C. Bouchet (Bordeaux, France), Z. Kmecová (Bratislava, Slovakia), P. Robillard (Bordeaux, France), C. Guignabert (Paris, France), L. Tu (Paris, France), F. Delcambre (Bordeaux, France), R. Marthan (Bordeaux, France), B. Muller (Bordeaux, France), C. Guibert (Bordeaux, France), V. Freund-Michel (Bordeaux, France)
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Short-term mechanisms activated by NGF to induce pulmonary arterial hyperreactivity
C. BOUCHET (Pessac, France), G. Cardouat (Pessac, France), M. Douart (Pessac, France), P. Robillard (Pessac, France), R. Marthan (Pessac, France), B. Muller (Pessac, France), C. Guibert (Pessac, France), V. Freund-Michel (Pessac, France)
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In vitro effects of vasodilatory drugs on BMPR2-silenced pulmonary microvascular endothelial cell function
B. Tielemans (Leuven, Belgium), A. Wagenaar (Leuven, Belgium), C. Belge (Leuven, Belgium), M. Delcroix (Leuven, Belgium), R. Quarck (Leuven, Belgium)
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BMPR2 mutations and iron metabolism in pulmonary arterial hypertension patients
V. Theobald (Heidelberg, Germany), E. Grünig (Heidelberg, Germany), N. Benjamin (Heidelberg, Germany), B. Egenlauf (Heidelberg, Germany), H. Gall (Gießen, Germany), A. Ghofrani (Gießen, Germany), M. Halank (Dresden, Germany), S. Harutyunova (Heidelberg, Germany), M. Hoeper (Hannover, Germany), D. Jonigk (Hannover, Germany), M. Schneider (Heidelberg, Germany), H. Seyfarth (Leipzig, Germany), S. Richtmann (Heidelberg, Germany), P. Xanthouli (Heidelberg, Germany), M. Muckenthaler (Heidelberg, Germany), C. Eichstaedt (Heidelberg, Germany)
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18-FDG uptake on PET-CT and metabolism in pulmonary arterial hypertension.
J. Osorio Trujillo (Barcelona, Spain), O. Tura-Ceide (Barcelona, Spain), J. Pavia (Barcelona, Spain), I. Vollmer (Barcelona, Spain), I. Blanco (Barcelona, Spain), V. Smolders (Barcelona, Spain), A. Ninerola (Barcelona, Spain), P. Paredes (Barcelona, Spain), J. Ruiz-Cabello (San Sebastian, Spain), M. Castellà (Barcelona, Spain), Y. Torralba (Barcelona, Spain), L. Sebastián (Barcelona, Spain), L. Piccari (Barcelona, Spain), V. Peinado (Barcelona, Spain), D. Aguilar (Madrid, Spain), J. Barberà (Madrid, Spain)
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LSC - 2021 - Direct effects of cigarette smoke in pulmonary arterial cells: Implications in arterial remodeling and vascular tone maintenance
S. Javier, J. Pino (francisco.pino@estudiante.uam.es / Universidad Autonoma of Madrid,Madrid), D. Labrousse-Arias (davidlabroussearias@gmail.com / Universidad Autonoma of Madrid,Madrid), C. Fernández-Pérez (Cintia.fernandez@uam.es / Universidad Autonoma of Madrid,Madrid), Laura, F. (Laura.fernandezblanco@estudiante.uam.es / Universidad Autonoma of Madrid,Madrid), B. Barreira (biancabarreira@med.ucm.es / Universidad Complutense of Madrid,Madrid), G. Mondéjar-Parreño (gemondej@ucm.es / Universidad Complutense of Madrid,Madrid), E. Alfaro-Arnedo (ealfaro@riojasalud.es / Centro de Investigación Biomédica de La Rioja,Logroño), I. P. López (iplgarcia@riojasalud.es / Centro de Investigación Biomédica de La Rioja,Logroño), S. Pérez-Rial (SPerezR@fjd.es / Biomedical Research Unit IIS-FJD,Madrid), G. Peces-Barba (GPeces@fjd.es / Biomedical Research Unit IIS-FJD,Madrid), J. G. Pichel (jgpichel@riojasalud.es / Centro de Investigación Biomédica de La Rioja,Logroño), V. Ivo Peinado (vpeinado@clinic.cat / Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer,Barcelona), Á. Cogolludo (acogolludo@med.ucm.es / Universidad Complutense of Madrid,Madrid), M. Jose Calzada Garcia (calzadamj@yahoo.com / Universidad Autonoma of Madrid,Madrid)
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Soluble guanylate cyclase stimulators revert in vitro cigarette smoke effects through JNK pathway normalization
A. Bosacoma (Barcelona, Spain), D. Aguilar (Barcelona, Spain), T. Paul (Barcelona, Spain), I. Blanco (Barcelona, Spain), O. Tura-Ceide (Barcelona, Spain), J. Barberà (Barcelona, Spain), V. Peinado (Barcelona, Spain)
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Altered gut microbiota in chronic thromboembolic pulmonary hypertension
T. Jujo (Chiba, Japan), Y. Ikubo (Chiba, Japan), K. Hosomi (Osaka, Japan), A. Naito (Chiba, Japan), J. Park (Osaka, Japan), H. Shoji (Chiba, Japan), R. Suda (Chiba, Japan), A. Sekine (Chiba, Japan), A. Shigeta (Chiba, Japan), S. Sakao (Chiba, Japan), N. Tanabe (Chiba, Japan), K. Mizuguchi (Osaka, Japan), J. Kunisawa (Osaka, Japan), K. Tatsumi (Chiba, Japan)
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Novel hypoxia system to assess endothelial dysfunction in chronic thromboembolic pulmonary hypertension (CTEPH)
Y. Roger (Barcelona, Spain), I. Almendros (Barcelona, Spain), E. Marhuenda (Barcelona, Spain), A. Ramirez (Barcelona, Spain), V. Peinado (Barcelona, Spain), I. Blanco (Barcelona, Spain), M. Castellà (Barcelona, Spain), J. Barberà (Barcelona, Spain), O. Tura-Ceide (Barcelona, Spain)
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Differential expression of plasma microRNAs in chronic thromboembolic pulmonary hypertension and pulmonary embolism related to occult cancer
J. Oto (Valencia, Spain), O. Tura-Ceide (Barcelona, Spain), V. Sánchez-López (Seville, Spain), C. Font (Barcelona, Spain), J. Osorio (Barcelona, Spain), C. Bonjoch (Barcelona, Spain), D. Hervás (Valencia, Spain), E. Arellano (Madrid, Spain), P. Medina (Valencia, Spain), I. Blanco (Barcelona, Spain), V. Peinado (Barcelona, Spain), J. Barberà (Barcelona, Spain), R. Otero (Seville, Spain)
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Pentastatin, matrikine of the type IV collagen a5 drives pulmonary hypertension via endothelial dysfunction
A. Mutgan (Graz, Austria), K. Jandl (Graz, Austria), L. Marsh (Graz, Austria), J. Hoffmann (Graz, Austria), E. Gschwandtner (Vienna, Austria), W. Klepetko (Vienna, Austria), A. Heinemann (Graz, Austria), H. Olschewski (Graz, Austria), A. Olschewski (Graz, Austria), M. Wygrecka (Giessen, Germany), G. Kwapiszewska (Graz, Austria)
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Estrogen and progestin induce the migration of pulmonary artery smooth muscle cells with the contractile phenotype via different mechanisms
W. Hu (Shanghai, China), S. Li (Shanghai, China), D. Liu (Shanghai, China)
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Genetic findings in a family with hereditary spherocytosis, haemolytic anaemia and pulmonary hypertension
M. Shaukat (Heidelberg, Germany), M. Lankeit (Berlin, Germany), D. Cao (Heidelberg, Germany), N. Benjamin (Heidelberg, Germany), E. Grünig (Heidelberg, Germany), C. Eichstaedt (Heidelberg, Germany)
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Pulmonary vein banding-induced pulmonary venous congestion causes pulmonary hypertension in rats.
J. Muenks (Gießen, Germany), B. Kojonazarov (Gießen, Germany), A. Sydykov (Gießen, Germany), N. Weissmann (Gießen, Germany), R. Schermuly (Gießen, Germany), M. Boehm (Gießen, Germany)
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Right ventricular function and lung perfusion in adaptive versus maladaptive experimental pulmonary hypertension
B. Kojonazarov (Gießen, Germany), W. Seeger (Gießen, Germany), R. Schermuly (Gießen, Germany)
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Late Breaking Abstract - Involvement of Orai1 Ca2+ channel in the pathogenesis of pulmonary arterial hypertension. Orai1 as a new potential therapeutic target ?
B. Masson (Le Plessis-Robinson, France), H. Le Ribeuz (Le Plessis-Robinson, France), J. Sabourin (Châtenay-Malabry, France), E. Woodhouse (Leeds, United Kingdom), R. Foster (Leeds, United Kingdom), Y. Ruchon (Le Plessis-Robinson, France), M. Dutheil (Le Plessis-Robinson, France), A. Boët (Le Plessis-Robinson, France), M. Ghigna (Le Plessis-Robinson, France), O. Mercier (Le Plessis-Robinson, France), D. Beech (Leeds, United Kingdom), J. Benitah (Châtenay-Malabry, France), M. Bailey (Leeds, United Kingdom), M. Humbert (Le Kremlin-Bicêtre, France), D. Montani (Le Kremlin-Bicêtre, France), V. Capuano (Le Plessis-Robinson, France), F. Antigny (Le Plessis-Robinson, France)
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Late Breaking Abstract - Implication of the KATP Sur2b/Kir6.1 in the physiopathology of pulmonary arterial hypertension
H. Le Ribeuz (Le plessis robinson, France), M. Dutheil (Le plessis robinson, France), V. Capuano (Le plessis robinson, France), O. Mercier (Le plessis robinson, France), M. Humbert (Le Kremlin Bicêtre, France), D. Montani (Le Kremlin Bicêtre, France), F. Antigny (Le plessis robinson, France)
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Late Breaking Abstract - Evidence of target engagement and pathway modulation: biomarker analysis of the phase 1b inhaled seralutinib study
R. Osterhout (San Diego, CA, United States of America), K. Highland (Cleveland, OH, United States of America), R. Frantz (Rochester, MN, United States of America), D. Nickle (San Diego, CA, United States of America), J. Mcconnell (Louisville, KY, United States of America), C. Burger (Jacksonville, FL, United States of America), R. Roscigno (San Diego, CA, United States of America), M. Cravets (San Diego, CA, United States of America), R. Mccaffrey (San Diego, CA, United States of America), L. Zisman (San Diego, CA, United States of America), J. Bruey (San Diego, CA, United States of America), L. Howard (London, United Kingdom)
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