N. Ubags (Epalinges, Switzerland), D. Bogaert (Edinburgh, United Kingdom)
Late Breaking Abstract - The innate immune collectin surfactant protein SP-D binds to SARS-CoV-2 spike-protein R. Arroyo (Cincinnati, United States of America), S. Grant (Cincinnati, United States of America), P. Kingma (Cincinnati, United States of America)
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LSC - 2020 - Streptococcus pneumoniae induces broad alterations in mitochondrial functions in human airway epithelial cells M. Aghapour (Magdeburg, Germany)
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COPD bronchial brush microbiome association with lung function and bronchial gene expression M. Yavari Ramsheh (Leicester , United Kingdom), K. Haldar (Leicester , United Kingdom), M. Barer (Leicester , United Kingdom), L. Ziegler-Heitbrock (Gauting, Germany), I. Gut (Barcelona , Spain), D. Singh (Manchester, United Kingdom), C. Brightling (Leicester , United Kingdom)
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Analysis of defective phagocytosis in COPD using super-resolution microscopy and automated bacterial quantification R. Wysoczanski (London, United Kingdom), J. Baker (London, United Kingdom), P. Fenwick (London, United Kingdom), E. Garcia (London, United Kingdom), S. Kumar (London, United Kingdom), M. Neil (London, United Kingdom), C. Dunsby (London, United Kingdom), P. French (London, United Kingdom), P. Barnes (London, United Kingdom), L. Donnelly (London, United Kingdom)
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Mesenchymal Stromal Cells Modulate the Systemic and Pulmonary Immune Cell Profile in Klebsiella Pneumoniae Induced Sepsis J. Brady (Galway, Ireland), S. Horie (Galway, Ireland), C. Masterson (Galway, Ireland), D. Byrnes (Galway, Ireland), H. Gonzalez (Galway, Ireland), D. O'Toole (Galway, Ireland), J. Laffey (Galway, Ireland)
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Tiotropium and fluticasone inhibit rhinovirus-induced mucin production via multiple mechanisms in differentiated airway epithelial cells Y. Wang (Leiden, Netherlands), D. Ninaber (Leiden, Netherlands), A. Van Schadewijk (Leiden, Netherlands), P. Hiemstra (Leiden, Netherlands)
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Relationship of the secretory immunoglobulin A (sIgA) and cortisol in pregnant women with chronic simple bronchitis associated with cytomegalovirus infection (CMVI) I. Gorikov (Blagoveshchensk (Amur Oblast), Russian Federation), I. Andrievskaya (Blagoveshchensk (Amur Oblast), Russian Federation), V. Kolosov (Blagoveshchensk (Amur Oblast), Russian Federation), L. Nakhamchen (Blagoveshchensk (Amur Oblast), Russian Federation), N. Ishutina (Blagoveshchensk (Amur Oblast), Russian Federation), I. Dovzhikova (Blagoveshchensk (Amur Oblast), Russian Federation)
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Human rhinovirus 16 infection of human macrophages disrupts Arpin expression impairing macrophage internalization: a potential link to exacerbation in chronic obstructive pulmonary disease? J. Jubrail (Edinburgh, United Kingdom), K. Africano Gomez (Paris, France), F. Herit (Paris, France), A. Mularski (Paris, France), P. Bourdoncle (Paris, France), L. Oberg (Gothenburg, Sweden), E. Israelsson (Gothenburg, Sweden), P. Regis-Burgel (Paris, France), G. Mayer (Gothenburg, Sweden), D. Cunoosamy (Massachusetts, United States of America), N. Kurian (Massachusetts, United States of America), F. Niedergang (Paris, France)
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Assessment of innate immunity mediators in the lung of COPD patients: relation with disease manifestations S. Baraldo (Padova (PD), Italy), P. Casolari (Ferrara (FE), Italy), M. Bonato (Padova (PD), Italy), N. Bernardinello (Padova (PD), Italy), L. Morandi (Ferrara (FE), Italy), M. Saetta (Padova (PD), Italy), A. Papi (Ferrara (FE), Italy), M. Contoli (Ferrara (FE), Italy)
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Macrophages in lung and innervating ganglia express TLR7 and release nitric oxide B. Proskocil (Portland, United States of America), A. Fryer (Portland, United States of America), D. Jacoby (Portland, United States of America), M. Drake (Portland, United States of America)
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Using mouse tracheal epithelial cells (mTECs) to uncover an antiviral role for BPIFB1. A. Alkhoshaiban (Sheffield, United Kingdom), P. Anujan (Sheffield, United Kingdom), L. Bingle (Sheffield, United Kingdom), C. Bingle (Sheffield, United Kingdom)
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Analysis of adaptive CD8+ T cell responses to Influenza A Virus in COPD patients S. Haines (Munich, Germany), I. Kammerl (Munich, Germany), T. Meul (Munich, Germany), A. Moosmann (Munich, Germany), T. Hofer (Munich, Germany), E. Nössner (Munich, Germany), M. Frankenberger (Munich, Germany), J. Behr (Munich, Germany), K. Milger-Kneidinger (Munich, Germany), S. Meiners (Munich, Germany)
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Interferon responses are dysfunctional in the epithelium of COPD Patients R. Lababidi (Oxford, United Kingdom), J. Cane (Oxford, United Kingdom), M. Bafadhel (Oxford, United Kingdom)
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Acute exacerbations of COPD induce a prothrombotic state through platelet-monocyte complexes, endothelial activation and increased thrombin generation L. van der Vorm (Apeldoorn, Netherlands), L. Li (Maastricht, Netherlands), D. Huskens (Maastricht, Netherlands), J. Hulstein (Apeldoorn, Netherlands), M. Roest (Maastricht, Netherlands), P. De Groot (Maastricht, Netherlands), H. Ten Cate (Maastricht, Netherlands), B. De Laat (Maastricht, Netherlands), J. Remijn (Apeldoorn, Netherlands), S. Simons (Maastricht, Netherlands)
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Sputum macrophages in chronic bronchitis are activated, steroid resistant and drive epithelial MUC5B M. Göransson (Gothenburg, Sweden), K. Andelid (Gothenburg, Sweden), A. Andersson (Gothenburg, Sweden), K. Öst (Gothenburg, Sweden), Z. Rojnik (Gothenburg, Sweden), L. Vanfleteren (Gothenburg, Sweden), S. Delaney (Gothenburg, Sweden)
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A high probability of short-range interactions between fibrocytes and CD8+ T cells potentiates the inflammatory response in chronic obstructive pulmonary disease (COPD) lungs E. Eyraud (Pessac, France), E. Maurat (Pessac, France), P. Vallois (Vandoeuvre-lès-Nancy, France), C. Contin-Bordes (Bordeaux, France), P. Girodet (Pessac, France), M. Thumerel (Pessac, France), P. Berger (Pessac, France), I. Dupin (Pessac, France)
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Improving automated cell recognition of sputum and BAL cells for Chipcytometry analysis S. Carstensen (Hannover, Germany), O. Holz (Hannover, Germany), J. Hohlfeld (Hannover, Germany), B. Rosenhahn (Hannover, Germany), M. Mueller (Hannover, Germany)
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