February

A pathway to keep all lifelong learners up to date: the ERS continuing professional development programme Amy Farr, Stefano Aliberti, Stelios Loukides, Gilbert Massard, Robert Primhak, Gernot G.U. Rohde, Nathalie Tabin, Carine Pannetier, Daiana Stolz Eur Respir J, 55 (2) 1902425; 10.1183/13993003.02425-2019
Minimising the environmental impact of inhaled therapies: problems with policy on low carbon inhalers Duncan Keeley, Jane E. Scullion, Omar S. Usmani Eur Respir J, 55 (2) 2000048; 10.1183/13993003.00048-2020
Immunotherapy for nonsmall cell lung cancer: a new therapeutic algorithm Thierry Berghmans, Anne-Marie Dingemans, Lizza E.L. Hendriks, Jacques Cadranel Eur Respir J, 55 (2) 1901907; 10.1183/13993003.01907-2019
The role of gene–environment interactions in lung disease: the urgent need for the exposome Craig E. Wheelock, Stephen M. Rappaport Eur Respir J, 55 (2) 1902064; 10.1183/13993003.02064-2019
Training curriculum for European thoracic surgeons: a joint initiative of the European Society of Thoracic Surgeons and the European Respiratory Society Gilbert Massard, Nathalie Tabin, Lars Konge, Anna Elisabeth Frick, Hasan Batirel, Alessandro Brunelli, Stefano Elia, Martin Huertgen, Laureano Molins, Kostas Papagiannopoulos, Dragan Subotic, Paul van Schil, Gonzalo Varela, Dirk van Raemdonck Eur Respir J, 55 (2) 1902012; 10.1183/13993003.02012-2019
Troponin as a biomarker for mortality in stable COPD Ulf Nilsson, Lowie E.G.W. Vanfleteren Eur Respir J, 55 (2) 1902447; 10.1183/13993003.02447-2019
Floating the invisible swan: noninvasive prediction of haemodynamics Vineet Agrawal, Evan L. Brittain Eur Respir J, 55 (2) 1902385; 10.1183/13993003.02385-2019
Incidental venous thromboembolism, detected by chance, but still venous thromboembolism Guy Meyer, Benjamin Planquette Eur Respir J, 55 (2) 2000028; 10.1183/13993003.00028-2020
No man is an island: e-cigarette, or vaping, associated lung injury in Europe Denitza P. Blagev Eur Respir J, 55 (2) 1902419; 10.1183/13993003.02419-2019
Exhaled volatile organic compounds for better asthma control: could it be a future noninvasive adherence test? Florence N. Schleich, Delphine Zanella, Jean-François Focant Eur Respir J, 55 (2) 1902112; 10.1183/13993003.02112-2019
Technical standards for respiratory oscillometry Gregory G. King, Jason Bates, Kenneth I. Berger, Peter Calverley, Pedro L. de Melo, Raffaele L. Dellacà, Ramon Farré, Graham L. Hall, Iulia Ioan, Charles G. Irvin, David W. Kaczka, David A. Kaminsky, Hajime Kurosawa, Enrico Lombardi, Geoffrey N. Maksym, François Marchal, Beno W. Oppenheimer, Shannon J. Simpson, Cindy Thamrin, Maarten van den Berge, Ellie Oostveen Eur Respir J, 55 (2) 1900753; 10.1183/13993003.00753-2019
ESR/ERS statement paper on lung cancer screening Hans-Ulrich Kauczor, Anne-Marie Baird, Torsten Gerriet Blum, Lorenzo Bonomo, Clementine Bostantzoglou, Otto Burghuber, Blanka Cepická, Alina Comanescu, Sébastien Couraud, Anand Devaraj, Vagn Jespersen, Sergey Morozov, Inbar Nardi Agmon, Nir Peled, Pippa Powell, Helmut Prosch, Sofia Ravara, Janette Rawlinson, Marie-Pierre Revel, Mario Silva, Annemiek Snoeckx, Bram van Ginneken, Jan P. van Meerbeeck, Constantine Vardavas, Oyunbileg von Stackelberg, Mina Gaga Eur Respir J, 55 (2) 1900506; 10.1183/13993003.00506-2019
ERS/TSANZ Task Force Statement on the management of reproduction and pregnancy in women with airways diseases Peter G. Middleton, Elisabeth J. Gade, Cristina Aguilera, Lucy MacKillop, Brenda M. Button, Courtney Coleman, Barbara Johnson, Charlotte Albrechtsen, Frank Edenborough, David Rigau, Peter G. Gibson, Vibeke Backer Eur Respir J, 55 (2) 1901208; 10.1183/13993003.01208-2019
High-sensitivity troponin I and all-cause mortality in patients with stable COPD: an analysis of the COSYCONET study Benjamin Waschki, Peter Alter, Tanja Zeller, Christina Magnussen, Johannes T. Neumann, Raphael Twerenbold, Christoph Sinning, Christian Herr, Kathrin Kahnert, Sebastian Fähndrich, Stefan Blankenberg, Klaus F. Rabe, Tobias Welte, Rudolf A. Jörres, Claus F. Vogelmeier, Robert Bals, Henrik Watz Eur Respir J, 55 (2) 1901314; 10.1183/13993003.01314-2019
Inhaled corticosteroid use and the incidence of lung cancer in COPD Samy Suissa, Sophie Dell'Aniello, Anne V. Gonzalez, Pierre Ernst Eur Respir J, 55 (2) 1901720; 10.1183/13993003.01720-2019
Dietary antioxidant intake in school age and lung function development up to adolescence Emmanouela Sdona, Jenny Hallberg, Niklas Andersson, Sandra Ekström, Susanne Rautiainen, Niclas Håkansson, Alicja Wolk, Inger Kull, Erik Melén, Anna Bergström Eur Respir J, 55 (2) 1900990; 10.1183/13993003.00990-2019
Noninvasive evaluation of pulmonary artery pressure during exercise: the importance of right atrial hypertension Masaru Obokata, Garvan C. Kane, Hidemi Sorimachi, Yogesh N.V. Reddy, Thomas P. Olson, Alexander C. Egbe, Vojtech Melenovsky, Barry A. Borlaug Eur Respir J, 55 (2) 1901617; 10.1183/13993003.01617-2019
Intensity and quality of exertional dyspnoea in patients with stable pulmonary hypertension Athénaïs Boucly, Capucine Morélot-Panzini, Gilles Garcia, Jason Weatherald, Xavier Jaïs, Laurent Savale, David Montani, Marc Humbert, Thomas Similowski, Olivier Sitbon, Pierantonio Laveneziana Eur Respir J, 55 (2) 1802108; 10.1183/13993003.02108-2018
Mendelian randomisation analysis of red cell distribution width in pulmonary arterial hypertension Anna Ulrich, John Wharton, Timothy E. Thayer, Emilia M. Swietlik, Tufik R. Assad, Ankit A. Desai, Stefan Gräf, Lars Harbaum, Marc Humbert, Nicholas W. Morrell, William C. Nichols, Florent Soubrier, Laura Southgate, David-Alexandre Trégouët, Richard C. Trembath, Evan L. Brittain, Martin R. Wilkins, Inga Prokopenko, Christopher J. Rhodes Eur Respir J, 55 (2) 1901486; 10.1183/13993003.01486-2019
Clinical implications of incidental venous thromboembolism in cancer patients Frits I. Mulder, Marcello Di Nisio, Cihan Ay, Marc Carrier, Floris T.M. Bosch, Annelise Segers, Noémie Kraaijpoel, Michael A. Grosso, George Zhang, Peter Verhamme, Tzu-Fei Wang, Jeffrey I. Weitz, Saskia Middeldorp, Gary Raskob, Ludo F.M. Beenen, Harry R. Büller, Nick van Es Eur Respir J, 55 (2) 1901697; 10.1183/13993003.01697-2019
CX3CR1–fractalkine axis drives kinetic changes of monocytes in fibrotic interstitial lung diseases Flavia R. Greiffo, Valeria Viteri-Alvarez, Marion Frankenberger, Daniela Dietel, Almudena Ortega-Gomez, Joyce S. Lee, Anne Hilgendorff, Jürgen Behr, Oliver Soehnlein, Oliver Eickelberg, Isis E. Fernandez Eur Respir J, 55 (2) 1900460; 10.1183/13993003.00460-2019
Airway G-CSF identifies neutrophilic inflammation and contributes to asthma progression Young-Min Kim, Hyekang Kim, Seungwon Lee, Sora Kim, Jong-Uk Lee, Youngwoo Choi, Han Wook Park, Gihoon You, Hansol Kang, Seyoung Lee, Jong-Sook Park, Yunji Park, Hae-Sim Park, Choon-Sik Park, Seung-Woo Lee Eur Respir J, 55 (2) 1900827; 10.1183/13993003.00827-2019
Early life exposure to air pollution and incidence of childhood asthma, allergic rhinitis and eczema Teresa To, Jingqin Zhu, Dave Stieb, Natasha Gray, Ivy Fong, Lauren Pinault, Michael Jerrett, Alain Robichaud, Richard Ménard, Aaron van Donkelaar, Randall V. Martin, Perry Hystad, Jeffrey R. Brook, Sharon Dell Eur Respir J, 55 (2) 1900913; 10.1183/13993003.00913-2019
Exhaled volatile organic compounds as markers for medication use in asthma Paul Brinkman, Waqar M. Ahmed, Cristina Gómez, Hugo H. Knobel, Hans Weda, Teunis J. Vink, Tamara M. Nijsen, Craig E. Wheelock, Sven-Erik Dahlen, Paolo Montuschi, Richard G. Knowles, Susanne J. Vijverberg, Anke H. Maitland-van der Zee, Peter J. Sterk, Stephen J. Fowler Eur Respir J, 55 (2) 1900544; 10.1183/13993003.00544-2019
Effect of asthma exacerbation during pregnancy in women with asthma: a population-based cohort study Kawsari Abdullah, Jingqin Zhu, Andrea Gershon, Sharon Dell, Teresa To Eur Respir J, 55 (2) 1901335; 10.1183/13993003.01335-2019
Differential DNA methylation in bronchial biopsies between persistent asthma and asthma in remission Cornelis J. Vermeulen, Cheng-Jian Xu, Judith M. Vonk, Nick H.T. ten Hacken, Wim Timens, Irene H. Heijink, Martijn C. Nawijn, Jeunard Boekhoudt, Antoon J. van Oosterhout, Karen Affleck, Markus Weckmann, Gerard H. Koppelman, Maarten van den Berge Eur Respir J, 55 (2) 1901280; 10.1183/13993003.01280-2019
Relationship of obstructive sleep apnoea severity and subclinical systemic atherosclerosis Soriul Kim, Ki Yeol Lee, Nan Hee Kim, Robert D. Abbott, Cherry Kim, Seung Ku Lee, Seong Hwan Kim, Chol Shin Eur Respir J, 55 (2) 1900959; 10.1183/13993003.00959-2019
Genomic characterisation of pulmonary subsolid nodules: mutational landscape and radiological features Yanmeng Li, Xiao Li, Hao Li, Yifan Zhao, Ziyang Liu, Kunkun Sun, Xiang Zhu, Qingyi Qi, Bei An, Danhua Shen, Ruoyan Li, Taorui Liu, Jiahui Mi, Lientu Wang, Fan Yang, Fan Bai, Jun Wang Eur Respir J, 55 (2) 1901409; 10.1183/13993003.01409-2019
PET/CT features of extrapulmonary tuberculosis at first clinical presentation: a cross-sectional observational ¹⁸F-FDG imaging study across six countries Jamshed Bomanji, Rajnish Sharma, Bhagwant R. Mittal, Sanjay Gambhir, Ahmad Qureshy, Shamim M.F. Begum, Diana Paez, Mike Sathekge, Mariza Vorster, Dragana Sobic Saranovic, Pawana Pusuwan, Vera Mann, Sobhan Vinjamuri, Alimuddin Zumla, Thomas N.B. Pascual Eur Respir J, 55 (2) 1901959; 10.1183/13993003.01959-2019
Genetic landscape of adult Langerhans cell histiocytosis with lung involvement Fanélie Jouenne, Sylvie Chevret, Emmanuelle Bugnet, Emmanuelle Clappier, Gwenaël Lorillon, Véronique Meignin, Aurélie Sadoux, Shannon Cohen, Alain Haziot, Alexandre How-Kit, Caroline Kannengiesser, Céleste Lebbé, Dominique Gossot, Samia Mourah, Abdellatif Tazi Eur Respir J, 55 (2) 1901190; 10.1183/13993003.01190-2019
Eight novel variants in the SLC34A2 gene in pulmonary alveolar microlithiasis Åsa Lina M. Jönsson, Elisabeth Bendstrup, Susie Mogensen, Elizabeth J. Kopras, Francis X. McCormack, Ilaria Campo, Francesca Mariani, Amparo Escribano-Montaner, Are M. Holm, Maria del Mar Martinez-Colls, Guillem Pintos-Morell, Camille Taillé, Bruno Crestani, Ole Hilberg, Jane Hvarregaard Christensen, Ulf Simonsen Eur Respir J, 55 (2) 1900806; 10.1183/13993003.00806-2019
Current perspectives on the role of interleukin-1 signalling in the pathogenesis of asthma and COPD Emmanuel T. Osei, Corry-Anke Brandsma, Wim Timens, Irene H. Heijink, Tillie-Louise Hackett Eur Respir J, 55 (2) 1900563; 10.1183/13993003.00563-2019
SABINA: global programme to evaluate prescriptions and clinical outcomes related to short-acting ß₂-agonist use in asthma Claudia S. Cabrera, Cassandra Nan, Niklas Lindarck, Maarten J.H.I. Beekman, Sofie Arnetorp, Ralf J.P. van der Valk Eur Respir J, 55 (2) 1901858; 10.1183/13993003.01858-2019
Pulmonary xenon-129 MRI: new opportunities to unravel enigmas in respiratory medicine Rachel L. Eddy, Grace Parraga Eur Respir J, 55 (2) 1901987; 10.1183/13993003.01987-2019
Attitudes of patients with chronic breathlessness towards treatment with opioids Cornelia A. Verberkt, Marieke H.J. van den Beuken-van Everdingen, Emiel F.M. Wouters, Daisy J.A. Janssen Eur Respir J, 55 (2) 1901752; 10.1183/13993003.01752-2019
Physiological predictors of exertional oxygen desaturation in patients with fibrotic interstitial lung disease Veronica Alfieri, Ernesto Crisafulli, Dina Visca, Wing Ho Chong, Carmel Stock, Letizia Mori, Angelo de Lauretis, Vicky Tsipouri, Felix Chua, Vasilis Kouranos, Maria Kokosi, Charlotte Hogben, Philip L. Molyneaux, Peter M. George, Toby M. Maher, Alfredo A. Chetta, Piersante Sestini, Athol U. Wells, Elisabetta A Renzoni Eur Respir J, 55 (2) 1901681; 10.1183/13993003.01681-2019
Discrepancies in reported versus measured nicotine content of e-cigarette refill liquids across nine European countries before and after the implementation of the EU Tobacco Products Directive Charis Girvalaki, Manolis Tzatzarakis, Alexander Vardavas, Christina N. Kyriakos, Katerina Nikitara, Polychronis Stivaktakis, Aristidis Tsatsakis, Constantine Vardavas Eur Respir J, 55 (2) 1900941; 10.1183/13993003.00941-2019
Pulmonary artery enlargement and mortality risk in moderate to severe COPD: results from COPDGene David C. LaFon, Surya P. Bhatt, Wassim W. Labaki, Farbod N. Rahaghi, Matthew Moll, Russ P. Bowler, Elizabeth A. Regan, Barry J. Make, James D. Crapo, Raul San Jose Estepar, Alejandro A. Diaz, Edwin K. Silverman, MeiLan K. Han, Brian Hobbs, Michael H. Cho, George R. Washko, Mark T. Dransfield, J. Michael Wells Eur Respir J, 55 (2) 1901812; 10.1183/13993003.01812-2019
Should we worry about bedaquiline exposure in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis? Jan-Willem C. Alffenaar, Onno W. Akkerman, Simon Tiberi, Giovanni Sotgiu, Giovanni Battista Migliori Eur Respir J, 55 (2) 1901908; 10.1183/13993003.01908-2019
An imported case of e-cigarette or vaping associated lung injury in Barcelona Gherzon Simón Casanova, Rosanel Amaro, Néstor Soler, Marcelo Sánchez, Joan Ramón Badía, Joan Albert Barberà, Alvar Agustí Eur Respir J, 55 (2) 1902076; 10.1183/13993003.02076-2019
Cost-effectiveness of ambulatory oxygen in improving quality of life in fibrotic lung disease: preliminary evidence from the AmbOx Trial Jennifer A. Whitty, Jenny Rankin, Dina Visca, Vicky Tsipouri, Letizia Mori, Lisa Spencer, Huzaifa Adamali, Toby M. Maher, Nicholas S. Hopkinson, Surinder S. Birring, Morag Farquhar, Athol U. Wells, Piersante Sestini, Elisabetta A. Renzoni Eur Respir J, 55 (2) 1901157; 10.1183/13993003.01157-2019
Longitudinal changes in airway hyperresponsiveness and COPD mortality Andreas A. Teferra, Judith M. Vonk, H. Marike Boezen Eur Respir J, 55 (2) 1901378; 10.1183/13993003.01378-2019
Diagnostic sensitivity of SILVAMP TB-LAM (FujiLAM) point-of-care urine assay for extra-pulmonary tuberculosis in people living with HIV Andrew D. Kerkhoff, Bianca Sossen, Charlotte Schutz, Elena Ivanova Reipold, Andre Trollip, Emmanuel Moreau, Samuel G. Schumacher, Rosie Burton, Amy Ward, Mark P. Nicol, Graeme Meintjes, Claudia M. Denkinger, Tobias Broger Eur Respir J, 55 (2) 1901259; 10.1183/13993003.01259-2019
Can circular RNAs be used as prenatal biomarkers for congenital diaphragmatic hernia? Richard Wagner, Aruni Jha, Lojine Ayoub, Shana Kahnamoui, Daywin Patel, Thomas H. Mahood, Andrew J. Halayko, Martin Lacher, Christopher D. Pascoe, Richard Keijzer Eur Respir J, 55 (2) 1900514; 10.1183/13993003.00514-2019
Impact of marijuana smoking on lung function in older persons Donald P. Tashkin, Michael D. Roth Eur Respir J, 55 (2) 1902328; 10.1183/13993003.02328-2019
Impact of marijuana smoking on lung function in older persons Wan C. Tan, Jean Bourbeau, Shawn D. Aaron, Don D. Sin Eur Respir J, 55 (2) 1902390; 10.1183/13993003.02390-2019
Defining “stable chronic hypercapnia” in patients with COPD: the physiological perspective Caroline Hedsund, Torgny Rostrup Wilcke, Ronan M.G. Berg Eur Respir J, 55 (2) 1902172; 10.1183/13993003.02172-2019
Defining “stable chronic hypercapnia” in patients with COPD: the physiological perspective Begum Ergan, Raffaele Scala, Wolfram Windisch Eur Respir J, 55 (2) 1902365; 10.1183/13993003.02365-2019
Prevalence of sarcoidosis-associated pulmonary hypertension: cumulative analysis of two PULSAR studies Stefan Pabst, Christian Grohé, Dirk Skowasch Eur Respir J, 55 (2) 1902223; 10.1183/13993003.02223-2019
“Truth is ever to be found in simplicity, and not in the multiplicity and confusion of things” — Sir Isaac Newton Jaclyn A. Smith, Mike A. Wortley, Sara Bonvini, Mark Birrell, Maria G. Belvisi Eur Respir J, 55 (2) 1901566; 10.1183/13993003.01566-2019
Author response: The human cough reflex has separate, distinct pathways Alyn H. Morice, Michael M. Kitt, Anthony P. Ford, Andrew M. Tershakovec, Wen-Chi Wu, Kayleigh Brindle, Rachel Thompson, Susannah Thackray-Nocera, Caroline Wright Eur Respir J, 55 (2) 1902312; 10.1183/13993003.02312-2019
GINA recommendations in adults with symptomatic mild asthma and a smoking history Neil C. Thomson, Rekha Chaudhuri Eur Respir J, 55 (2) 1902043; 10.1183/13993003.02043-2019
GINA recommendations in adults with symptomatic mild asthma and a smoking history Helen K. Reddel Eur Respir J, 55 (2) 2000068; 10.1183/13993003.00068-2020
Electrical stimulation in obstructive sleep apnoea: the less invasive the better? Martino Pengo, Esther Irene Schwarz, Joerg Steier Eur Respir J, 55 (2) 1902013; 10.1183/13993003.02013-2019