Novel mechanisms elucidated by translational studies of asthma

Poster Discussion
Chairs: F. Polverino (Tucson, United States of America), H. Smits (Leiden, Netherlands)
LSC - 2019 - Anti-IL5 in mild asthma alters rhinovirus-induced macrophage, B cell and neutrophil responses
Y. Sabogal Piñeros (Amsterdam, Netherlands), S. Bal (Amsterdam, Netherlands), M. Van De Pol (Amsterdam, Netherlands), B. Smids (Amsterdam, Netherlands), T. Dekker (Amsterdam, Netherlands), A. Dijkhuis (Amsterdam, Netherlands), P. Brinkman (Amsterdam, Netherlands), K. Van Der Sluijs (Amsterdam, Netherlands), K. Zwinderman (Amsterdam, Netherlands), C. Majoor (Amsterdam, Netherlands), P. Bonta (Amsterdam, Netherlands), L. Ravanetti (Amsterdam, Netherlands), P. Sterk (Amsterdam, Netherlands), R. Lutter (Amsterdam, Netherlands)
Congress or journal article abstract
Congress or journal article abstract
The role of eosinophils in airway hyperresponsiveness in diet-induced obese mice
G. Calco (Portland, United States of America), B. Proskocil (Portland, United States of America), D. Jacoby (Portland, United States of America), A. Fryer (Portland, United States of America), Z. Nie (Portland, United States of America)
Congress or journal article abstract
Congress or journal article abstract
Biological role of lung-resident and inflammatory eosinophils in severe non-allergic eosinophilic asthma
A. Januskevicius (Kaunas, Lithuania), I. Janulaityte (Kaunas, Lithuania), V. Kalinauskaite-Zukauske (Kaunas, Lithuania), R. Gosens (Groningen, Netherlands), A. Rimkunas (Kaunas, Lithuania), B. Tamasauskaite (Kaunas, Lithuania), K. Malakauskas (Kaunas, Lithuania)
Congress or journal article abstract
Congress or journal article abstract
miR-122-5p and miR-191-5p are increased in plasma small extracellular vesicles in asthma
T. Bahmer (Hamburg, Germany), S. Krauss-Etschmann (Borstel, Germany), D. Buschmann (Munich, Germany), J. Behrends (Borstel, Germany), H. Watz (Hamburg, Germany), A. Kirsten (Hamburg, Germany), F. Pedersen (Hamburg, Germany), B. Waschki (Hamburg, Germany), O. Fuchs (Bern, Switzerland), M. Pfaffl (Munich, Germany), E. Von Mutius (Munich, Germany), K. Rabe (Hamburg, Germany), G. Hansen (Hannover, Germany), M. Kopp (Lübeck, Germany), I. König (Lübeck, Germany), S. Bartel (Groningen, Netherlands)
Congress or journal article abstract
Congress or journal article abstract
Altered mitochondrial reactive oxygen species (ROS) production in airway smooth muscle cells of severe asthma.
B. Xu (Shenzhen, China), S. Cakir (London, United Kingdom), C. Badhan (London, United Kingdom), C. Hui (Shenzhen, China), K. Chung (London, United Kingdom), P. Bhavsar (London, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Platelet indices as inflammatory markers in stable COPD
I. Hlapcic (Zagreb, Croatia), M. Grdic Rajkovic (Zagreb, Croatia), A. Hulina Tomaškovic (Zagreb, Croatia), A. Somborac Bacura (Zagreb, Croatia), I. Rako (Zagreb, Croatia), A. Vukic Dugac (Zagreb, Croatia), L. Rumora (Zagreb, Croatia)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Il-4 and IL-13 act independently and synergistically to drive type 2 inflammation
A. Le Floc'H (Tarrytown, United States of America), J. Allinne (Tarrytown, United States of America), K. Nagashima (Tarrytown, United States of America), G. Scott (Tarrytown, United States of America), D. Birchard (Tarrytown, United States of America), S. Asrat (Tarrytown, United States of America), M. Sleeman (Tarrytown, United States of America), A. Murphy (Tarrytown, United States of America), J. Orengo (Tarrytown, United States of America)
Congress or journal article abstract
Congress or journal article abstract
Endobronchial biopsy gene expression between different severe asthma inflammatory phenotypes
S. Sánchez-Ovando (Newcastle, Australia), K. Baines (Newcastle, Australia), D. Barker (Newcastle, Australia), P. Wark (Newcastle, Australia), J. Simpson (Newcastle, Australia)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Eosinophils promote airway smooth muscle cells differentiation to the contractile phenotype in asthma
I. Janulaityte (Kaunas, Lithuania), A. Januskevicius (Kaunas, Lithuania), V. Kalinauskaite-Zukauske (Kaunas, Lithuania), R. Gosens (Kaunas, Lithuania), A. Rimkunas (Kaunas, Lithuania), G. Gabuzeviciute (Kaunas, Lithuania), K. Malakauskas (Kaunas, Lithuania)
Congress or journal article abstract
Congress or journal article abstract
IL-13 regulates cilia loss and localization of cp110 in human nasal epithelium
J. LIU (singapore, Singapore), Y. Li (singapore, Singapore), H. Ong (singapore, Singapore), K. Tan (singapore, Singapore), T. He (singapore, Singapore), K. Thong (singapore, Singapore), Y. Ong (singapore, Singapore), D. Wang (singapore, Singapore)
Congress or journal article abstract
Congress or journal article abstract
Distribution of Innate Lymphoid Cell populations in blood in different inflammatory phenotypes of asthma
G. Jorgensen (Copenhagen, Denmark), T. Petersen (Copenhagen, Denmark), A. Silberbrandt (Copenhagen, Denmark), L. Pflüger (Copenhagen, Denmark), M. Hvidtfeldt (Copenhagen, Denmark), C. Porsbjerg (Copenhagen, Denmark), C. Bonefeld (Copenhagen, Denmark), A. Sverrild (Copenhagen, Denmark)
Congress or journal article abstract
Congress or journal article abstract
The fraction of circulating type 2 innate lymphoid cells in peripheral blood is associated with asthma severity
A. Silberbrandt (Copenhagen, Denmark), A. Sverrild (Copenhagen, Denmark), G. Jørgensen (Copenhagen, Denmark), M. Hvidtfeldt (Copenhagen, Denmark), L. Frøssing (Copenhagen, Denmark), L. Pfluger (Copenhagen, Denmark), T. Petersen (Copenhagen, Denmark), C. Bonefeld (Copenhagen, Denmark), C. Porsbjerg (Copenhagen, Denmark)
Congress or journal article abstract
Congress or journal article abstract
Analysis of micronuclei in buccal epithelial cells from asthmatic patients
A. Lintsov (St.Petersburg, Russian Federation), N. Pleskach (St.Petersburg, Russian Federation), I. Spivak (St.Petersburg, Russian Federation), P. Slizhov (St.Petersburg, Russian Federation), S. Shevelev (St.Petersburg, Russian Federation), B. Uslontsev (St.Petersburg, Russian Federation), V. Trofimov (St.Petersburg, Russian Federation), V. Mikhelson (St.Petersburg, Russian Federation)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Eosinophilopoietins receptors, TGF-ß1 and outer-membrane integrins expression of lung-resident and inflammatory eosinophils in severe non-allergic eosinophilic asthma
A. Januskevicius (Kaunas, Lithuania), I. Janulaityte (Kaunas, Lithuania), V. Kalinauskaite-Zukauske (Kaunas, Lithuania), R. Gosens (Groningen, Netherlands), A. Rimkunas (Kaunas, Lithuania), B. Tamasauskaite (Kaunas, Lithuania), K. Malakauskas (Kaunas, Lithuania)
Congress or journal article abstract
Congress or journal article abstract
Optogenetic activation of mouse airway parasympathetic neurons to provoke bronchoconstriction
A. Pincus (Portland, United States of America), A. Fryer (Portland, United States of America), D. Jacoby (Portland, United States of America)
Congress or journal article abstract
Congress or journal article abstract
Influence of IL-17 on transcriptional profiles of lung and peribronchial lymph nodes dendritic cells in steady and antigen exposed conditions
A. Jirmo (Hannover, Germany), D. Deluca (Hannover, Germany), R. Grychtol (Hannover, Germany), O. Dittrich- Breiholz (Hannover, Germany), C. Happle (Hannover, Germany), G. Hansen (Hannover, Germany)
Congress or journal article abstract
Congress or journal article abstract
Soluble biglycan promotes ovalbumin induced airway inflammation by modulating dendritic cell function in mice
A. Zech (Vienna, Austria), S. Cicko (Freiburg, Germany), M. Idzko (Vienna, Austria)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Increased METEORIN-LIKE (ML) expression promotes lung inflammation in asthma.
X. Yao (Nanjing, China), X. Yan (Nanjing, China), M. Jia (Nanjing, China), J. Xu (Nanjing, China), Y. Meng (Nanjing, China), J. Jiang (Nanjing, China), X. Jiang (Nanjing, China), Y. Yang (Nanjing, China), Y. Ou (Nanjing, China), J. Zhou (Nanjing, China), S. Pavlidis (London, United Kingdom), S. Mumby (London, United Kingdom), F. Chung (London, United Kingdom), I. Adcock (London, United Kingdom), H. Jung (Seoul, Republic of Korea), H. Kim (Seoul, Republic of Korea), Y. Cho (Seoul, Republic of Korea), T. Kim (Seoul, Republic of Korea), M. Huang (Nanjing, China)
Congress or journal article abstract
Congress or journal article abstract