COPD – a disease of accelerated ageing?
Hot topicsChairs: I. M. Adcock (London, United Kingdom), P. J. Barnes (London, United Kingdom)
Aims: The hot topic will:
• describe the effect of aging on normal lung function;
• demonstrate how models of ageing may provide insights into emphysematous processes;
• describe the role of oxidative stress, DNA repair, apoptosis and sirtuins in emphysema;
• highlight potential therapeutic targets that may protect the lung from aging and emphysema.