April

The pulmonary haemodynamics during exercise – research network (PEX-NET) ERS Clinical Research Collaboration: investigating the prognostic relevance of exercise haemodynamics Gabor Kovacs, Philippe Herve, Horst Olschewski Eur Respir J, 53 (4) 1900458; 10.1183/13993003.00458-2019
Is it time to move away from short-acting beta-agonists in asthma management? Matthew J. Martin, Tim W. Harrison Eur Respir J, 53 (4) 1802223; 10.1183/13993003.02223-2018
Improvements in air quality: whose lungs benefit? Ulrike Gehring, Gerard H. Koppelman Eur Respir J, 53 (4) 1900365; 10.1183/13993003.00365-2019
Delivering high value therapies in COPD: the secret is in the marketing Helen Ashdown, Michael Steiner Eur Respir J, 53 (4) 1900215; 10.1183/13993003.00215-2019
MicroRNAs in COPD: small molecules with big potential Brian D. Hobbs, Kelan G. Tantisira Eur Respir J, 53 (4) 1900515; 10.1183/13993003.00515-2019
The Medusa faces of dyspnoea in COPD Emiel F.M. Wouters Eur Respir J, 53 (4) 1900487; 10.1183/13993003.00487-2019
Exercising our options: comparing effects of exercise and positive expiratory pressure on mucociliary clearance Scott H. Donaldson Eur Respir J, 53 (4) 1900510; 10.1183/13993003.00510-2019
Protecting those who serve: are we doing enough to prevent tuberculosis in healthcare workers? Jennifer Furin, Giovanni Sotgiu Eur Respir J, 53 (4) 1900485; 10.1183/13993003.00485-2019
Predicting respiratory failure in amyotrophic lateral sclerosis: recruiting a few good pulmonologists Noah Lechtzin Eur Respir J, 53 (4) 1900360; 10.1183/13993003.00360-2019
Electronic clinical decision support system (eCDSS) in the management of asthma: from theory to practice Jean Bousquet Eur Respir J, 53 (4) 1900339; 10.1183/13993003.00339-2019
The unknown pathophysiological relevance of right ventricular hypertrophy in pulmonary arterial hypertension Frances S. de Man, M. Louis Handoko, Anton Vonk-Noordegraaf Eur Respir J, 53 (4) 1900255; 10.1183/13993003.00255-2019
Benefits of improved air quality on ageing lungs: impacts of genetics and obesity Anke Hüls, Dorothee Sugiri, Michael J. Abramson, Barbara Hoffmann, Holger Schwender, Katja Ickstadt, Ursula Krämer, Tamara Schikowski Eur Respir J, 53 (4) 1801780; 10.1183/13993003.01780-2018
Interdisciplinary COPD intervention in primary care: a cluster randomised controlled trial Jenifer Liang, Michael J. Abramson, Grant Russell, Anne E. Holland, Nicholas A. Zwar, Billie Bonevski, Ajay Mahal, Paula Eustace, Eldho Paul, Kirsten Phillips, Narelle S. Cox, Sally Wilson, Johnson George Eur Respir J, 53 (4) 1801530; 10.1183/13993003.01530-2018
Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD Alen Faiz, Katrina Steiling, Mirjam P. Roffel, Dirkje S. Postma, Avrum Spira, Marc E. Lenburg, Malte Borggrewe, Tim R. Eijgenraam, Marnix R. Jonker, Gerard H. Koppelman, Simon D. Pouwels, Gang Liu, Yuriy O. Alekseyev, Stephen Lam, Pieter S. Hiemstra, Peter J. Sterk, Wim Timens, Corry-Anke Brandsma, Irene H. Heijink, Maarten van den Berge Eur Respir J, 53 (4) 1801202; 10.1183/13993003.01202-2018
Exercise intolerance in comorbid COPD and heart failure: the role of impaired aerobic function Alcides Rocha, Flavio F. Arbex, Priscila A. Sperandio, Frederico Mancuso, Mathieu Marillier, Anne-Catherine Bernard, Maria Clara N. Alencar, Denis E. O'Donnell, J. Alberto Neder Eur Respir J, 53 (4) 1802386; 10.1183/13993003.02386-2018
Effects of exercise and airway clearance (positive expiratory pressure) on mucus clearance in cystic fibrosis: a randomised crossover trial Tiffany J. Dwyer, Evangelia Daviskas, Rahizan Zainuldin, Jordan Verschuer, Stefan Eberl, Peter T.P. Bye, Jennifer A. Alison Eur Respir J, 53 (4) 1801793; 10.1183/13993003.01793-2018
Latent tuberculosis infection in healthcare workers in low- and middle-income countries: an updated systematic review Lika Apriani, Susan McAllister, Katrina Sharples, Bachti Alisjahbana, Rovina Ruslami, Philip C. Hill, Dick Menzies Eur Respir J, 53 (4) 1801789; 10.1183/13993003.01789-2018
Telomere length and genetic variant associations with interstitial lung disease progression and survival Chad A. Newton, Justin M. Oldham, Brett Ley, Vikram Anand, Ayodeji Adegunsoye, Gabrielle Liu, Kiran Batra, Jose Torrealba, Julia Kozlitina, Craig Glazer, Mary E. Strek, Paul J. Wolters, Imre Noth, Christine Kim Garcia Eur Respir J, 53 (4) 1801641; 10.1183/13993003.01641-2018
Artificial intelligence outperforms pulmonologists in the interpretation of pulmonary function tests Marko Topalovic, Nilakash Das, Pierre-Régis Burgel, Marc Daenen, Eric Derom, Christel Haenebalcke, Rob Janssen, Huib A.M. Kerstjens, Giuseppe Liistro, Renaud Louis, Vincent Ninane, Christophe Pison, Marc Schlesser, Piet Vercauter, Claus F. Vogelmeier, Emiel Wouters, Jokke Wynants, Wim Janssens Eur Respir J, 53 (4) 1801660; 10.1183/13993003.01660-2018
Development of a prognostic model of respiratory insufficiency or death in amyotrophic lateral sclerosis Jason Ackrivo, John Hansen-Flaschen, E. Paul Wileyto, Richard J. Schwab, Lauren Elman, Steven M. Kawut Eur Respir J, 53 (4) 1802237; 10.1183/13993003.02237-2018
Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks David S. Hui, Benny K. Chow, Thomas Lo, Owen T.Y. Tsang, Fanny W. Ko, Susanna S. Ng, Tony Gin, Matthew T.V. Chan Eur Respir J, 53 (4) 1802339; 10.1183/13993003.02339-2018
IL-17F, rather than IL-17A, underlies airway inflammation in a steroid-insensitive toluene diisocyanate-induced asthma model Rongchang Chen, Qingling Zhang, Shuyu Chen, Haixiong Tang, Peikai Huang, Shushan Wei, Zhenyu Liang, Xin Chen, Ailin Tao, Lihong Yao Eur Respir J, 53 (4) 1801510; 10.1183/13993003.01510-2018
The Electronic Asthma Management System (eAMS) improves primary care asthma management Samir Gupta, Courtney Price, Gina Agarwal, David Chan, Sanjeev Goel, Louis-Philippe Boulet, Alan G. Kaplan, Gerald Lebovic, Muhammad Mamdani, Sharon E. Straus Eur Respir J, 53 (4) 1802241; 10.1183/13993003.02241-2018
Dynamic hyperinflation impairs daily life activity in asthma Akke-Nynke van der Meer, Kim de Jong, Aranka Hoekstra-Kuik, Elisabeth H. Bel, Anneke ten Brinke Eur Respir J, 53 (4) 1801500; 10.1183/13993003.01500-2018
Changing prevalence of current asthma and inhaled corticosteroid treatment in the UK: population-based cohort 2006–2016 Chloe I. Bloom, Sejal Saglani, Johanna Feary, Debbie Jarvis, Jennifer K. Quint Eur Respir J, 53 (4) 1802130; 10.1183/13993003.02130-2018
Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course Herman T. den Dekker, Kimberley Burrows, Janine F. Felix, Lucas A. Salas, Ivana Nedeljkovic, Jin Yao, Sheryl L. Rifas-Shiman, Carlos Ruiz-Arenas, N. Amin, Mariona Bustamante, Dawn L. DeMeo, A. John Henderson, Caitlin G. Howe, Marie-France Hivert, M. Arfan Ikram, Johan C. de Jongste, Lies Lahousse, Pooja R. Mandaviya, Joyce B. van Meurs, Mariona Pinart, Gemma C. Sharp, Lisette Stolk, André G. Uitterlinden, Josep M. Anto, Augusto A. Litonjua, Carrie V. Breton, Guy G. Brusselle, Jordi Sunyer, George Davey Smith, Caroline L. Relton, Vincent W.V. Jaddoe, Liesbeth Duijts Eur Respir J, 53 (4) 1801795; 10.1183/13993003.01795-2018
Analysis of the MILES cohort reveals determinants of disease progression and treatment response in lymphangioleiomyomatosis Nishant Gupta, Hye-Seung Lee, Lisa R. Young, Charlie Strange, Joel Moss, Lianne G. Singer, Koh Nakata, Alan F. Barker, Jeffrey T. Chapman, Mark L. Brantly, James M. Stocks, Kevin K. Brown, Joseph P. Lynch, Hilary J. Goldberg, Gregory P. Downey, Angelo M. Taveira-DaSilva, Jeffrey P. Krischer, Kenneth Setchell, Bruce C. Trapnell, Yoshikazu Inoue, Francis X. McCormack Eur Respir J, 53 (4) 1802066; 10.1183/13993003.02066-2018
Introduction to precision medicine in COPD Janice M. Leung, Ma'en Obeidat, Mohsen Sadatsafavi, Don D. Sin Eur Respir J, 53 (4) 1802460; 10.1183/13993003.02460-2018
Of the need to reconcile discrepancies between two different reference equations for combined single-breath D_LNO–D_LCO in systemic sclerosis Thomas Radtke, Thông Hua-Huy, Holger Dressel, Anh Tuan Dinh-Xuan Eur Respir J, 53 (4) 1802109; 10.1183/13993003.02109-2018
Cytomegalovirus: an unrecognised potential contributor to cystic fibrosis disease progression? Michael D. Parkins, Kathleen J. Ramos, Christopher H. Goss, Ranjani Somayaji Eur Respir J, 53 (4) 1801727; 10.1183/13993003.01727-2018
Extracorporeal membrane oxygenation and surgical embolectomy for high-risk pulmonary embolism Fabio Ius, Marius M. Hoeper, Christine Fegbeutel, Christian Kühn, Karen Olsson, Nurbol Koigeldiyev, Igor Tudorache, Gregor Warnecke, Jörg Optenhöfel, Jakob Ono Puntigam, Andreas Schäfer, Bernhard C. Meyer, Jan B. Hinrichs, Johann Bauersachs, Axel Haverich, Serghei Cebotari Eur Respir J, 53 (4) 1801773; 10.1183/13993003.01773-2018
Levofloxacin pharmacokinetics, pharmacodynamics and outcome in multidrug-resistant tuberculosis patients Samiksha Ghimire, Bhagwan Maharjan, Erwin M. Jongedijk, Jos G.W. Kosterink, Gokarna R. Ghimire, Daan J. Touw, Tjip S. van der Werf, Bhabana Shrestha, Jan-Willem C. Alffenaar Eur Respir J, 53 (4) 1802107; 10.1183/13993003.02107-2018
Therapeutic effects of nintedanib are not influenced by emphysema in the INPULSIS trials Vincent Cottin, Arata Azuma, Ganesh Raghu, Wibke Stansen, Susanne Stowasser, Rozsa Schlenker-Herceg, Martin Kolb Eur Respir J, 53 (4) 1801655; 10.1183/13993003.01655-2018
Transcutaneous carbon dioxide measurement is not a reliable alternative to arterial blood gas sampling in the acute medical setting Victoria Mummery, Eleanor Rogers, Vijay Padmanaban, Dionne Matthew, Thomas Woodcock, Susannah Bloch Eur Respir J, 53 (4) 1801726; 10.1183/13993003.01726-2018
The clinical impact of Pseudomonas aeruginosa eradication in bronchiectasis in a Dutch referral centre Angelina Pieters, Marleen Bakker, Rogier A.S. Hoek, Josje Altenburg, Mireille van Westreenen, Joachim G.J.V. Aerts, Menno M. van der Eerden Eur Respir J, 53 (4) 1802081; 10.1183/13993003.02081-2018
Ventricular mass as a prognostic imaging biomarker in incident pulmonary arterial hypertension Catherine E. Simpson, Rachel L. Damico, Todd M. Kolb, Stephen C. Mathai, Rubina M. Khair, Takahiro Sato, Khalil Bourji, Ryan J. Tedford, Stefan L. Zimmerman, Paul M. Hassoun Eur Respir J, 53 (4) 1802067; 10.1183/13993003.02067-2018
Neutrophil extracellular traps in ex vivo lung perfusion perfusate predict the clinical outcome of lung transplant recipients Lindsay Caldarone, Andrea Mariscal, Andrew Sage, Meraj Khan, Stephen Juvet, Tereza Martinu, Ricardo Zamel, Marcelo Cypel, Mingyao Liu, Nades Palaniyar, Shaf Keshavjee Eur Respir J, 53 (4) 1801736; 10.1183/13993003.01736-2018
The importance of differentiating behavioural and psychological treatment effects from placebo in respiratory interventions Ben Ainsworth, Doug Hardman, Mike Thomas Eur Respir J, 53 (4) 1900156; 10.1183/13993003.00156-2019
Triple therapy for all patients with severe symptomatic COPD at risk of exacerbations Alberto Papi, Stefano Petruzzelli, Stefano Vezzoli, George Georges, Leonardo M. Fabbri Eur Respir J, 53 (4) 1900147; 10.1183/13993003.00147-2019
Triple therapy in COPD: only for the right patient Samy Suissa, Amnon Ariel Eur Respir J, 53 (4) 1900394; 10.1183/13993003.00394-2019
Asthma paradoxes: time for a new approach across the spectrum of asthma severity Luis J. Nannini Eur Respir J, 53 (4) 1802329; 10.1183/13993003.02329-2018
Asthma paradoxes: time for a new approach across the spectrum of asthma severity Richard Beasley, Grace Bird, James Harper, Mark Weatherall Eur Respir J, 53 (4) 1900218; 10.1183/13993003.00218-2019