September

After the asthmas: Star Wars and Star Trek Andrew Bush, Ian D. Pavord Eur Respir J, 50 (3) 1701362; 10.1183/13993003.01362-2017
Phase three studies of biologics for severe asthma: could do better? Douglas S. Robinson, Harsha H. Kariyawasam, Liam G. Heaney Eur Respir J, 50 (3) 1701108; 10.1183/13993003.01108-2017
Challenging the concept of adding more drugs in pulmonary arterial hypertension Caio J. C. dos Santos Fernandes, Marc Humbert, Rogerio Souza Eur Respir J, 50 (3) 1701527; 10.1183/13993003.01527-2017
Targeting bone morphogenic protein receptor 2 (BMPR2) signalling to treat pulmonary arterial hypertension Lewis J. Rubin Eur Respir J, 50 (3) 1701370; 10.1183/13993003.01370-2017
Treating anxious expectations can improve dyspnoea in patients with COPD Andreas von Leupoldt Eur Respir J, 50 (3) 1701352; 10.1183/13993003.01352-2017
Haemophilus influenzae biofilms in primary ciliary dyskinesia: a moving story Amelia Shoemark Eur Respir J, 50 (3) 1701369; 10.1183/13993003.01369-2017
Inhaled budesonide for acute mountain sickness Robert Naeije, Erik R. Swenson Eur Respir J, 50 (3) 1701355; 10.1183/13993003.01355-2017
In memoriam: Professor Philip H. Quanjer Janet Stocks, Irene Steenbruggen Eur Respir J, 50 (3) 1701660; 10.1183/13993003.01660-2017
Prevention of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline Jadwiga A. Wedzicha, Peter M.A. Calverley, Richard K. Albert, Antonio Anzueto, Gerard J. Criner, John R. Hurst, Marc Miravitlles, Alberto Papi, Klaus F. Rabe, David Rigau, Pawel Sliwinski, Thomy Tonia, Jørgen Vestbo, Kevin C. Wilson, Jerry A. Krishnan Eur Respir J, 50 (3) 1602265; 10.1183/13993003.02265-2016
European Respiratory Society guidelines for the management of adult bronchiectasis Eva Polverino, Pieter C. Goeminne, Melissa J. McDonnell, Stefano Aliberti, Sara E. Marshall, Michael R. Loebinger, Marlene Murris, Rafael Cantón, Antoni Torres, Katerina Dimakou, Anthony De Soyza, Adam T. Hill, Charles S. Haworth, Montserrat Vendrell, Felix C. Ringshausen, Dragan Subotic, Robert Wilson, Jordi Vilaró, Bjorn Stallberg, Tobias Welte, Gernot Rohde, Francesco Blasi, Stuart Elborn, Marta Almagro, Alan Timothy, Thomas Ruddy, Thomy Tonia, David Rigau, James D. Chalmers Eur Respir J, 50 (3) 1700629; 10.1183/13993003.00629-2017
Inducible laryngeal obstruction: an official joint European Respiratory Society and European Laryngological Society statement Thomas Halvorsen, Emil Schwarz Walsted, Caterina Bucca, Andrew Bush, Giovanna Cantarella, Gerhard Friedrich, Felix J.F. Herth, James H. Hull, Harald Jung, Robert Maat, Leif Nordang, Marc Remacle, Niels Rasmussen, Janet A. Wilson, John-Helge Heimdal Eur Respir J, 50 (3) 1602221; 10.1183/13993003.02221-2016
International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia Antoni Torres, Michael S. Niederman, Jean Chastre, Santiago Ewig, Patricia Fernandez-Vandellos, Hakan Hanberger, Marin Kollef, Gianluigi Li Bassi, Carlos M. Luna, Ignacio Martin-Loeches, J. Artur Paiva, Robert C. Read, David Rigau, Jean François Timsit, Tobias Welte, Richard Wunderink Eur Respir J, 50 (3) 1700582; 10.1183/13993003.00582-2017
Official ERS technical standards: Global Lung Function Initiative reference values for the carbon monoxide transfer factor for Caucasians Sanja Stanojevic, Brian L. Graham, Brendan G. Cooper, Bruce R. Thompson, Kim W. Carter, Richard W. Francis, Graham L. Hall Eur Respir J, 50 (3) 1700010; 10.1183/13993003.00010-2017
RESPITE: switching to riociguat in pulmonary arterial hypertension patients with inadequate response to phosphodiesterase-5 inhibitors Marius M. Hoeper, Gérald Simonneau, Paul A. Corris, Hossein-Ardeschir Ghofrani, James R. Klinger, David Langleben, Robert Naeije, Pavel Jansa, Stephan Rosenkranz, Laura Scelsi, Ekkehard Grünig, Carmine Dario Vizza, MiKyung Chang, Pablo Colorado, Christian Meier, Dennis Busse, Raymond L. Benza Eur Respir J, 50 (3) 1602425; 10.1183/13993003.02425-2016
Randomised placebo-controlled safety and tolerability trial of FK506 (tacrolimus) for pulmonary arterial hypertension Edda Spiekerkoetter, Yon K. Sung, Deepti Sudheendra, Valerie Scott, Patricia Del Rosario, Matthew Bill, Francois Haddad, Janel Long-Boyle, Haley Hedlin, Roham T. Zamanian Eur Respir J, 50 (3) 1602449; 10.1183/13993003.02449-2016
Survival in individuals with severe alpha 1-antitrypsin deficiency (PiZZ) in comparison to a general population with known smoking habits Hanan A. Tanash, Magnus Ekström, Eva Rönmark, Anne Lindberg, Eeva Piitulainen Eur Respir J, 50 (3) 1700198; 10.1183/13993003.00198-2017
Interplay between cigarette smoking and pulmonary reverse lipid transport Éric Jubinville, Maude Talbot, Jean-Christophe Bérubé, Mélanie Hamel-Auger, Michaël Maranda-Robitaille, Marie-Josée Beaulieu, Sophie Aubin, Marie-Ève Paré, David G. Kallend, Benoit Arsenault, Yohan Bossé, Mathieu C. Morissette Eur Respir J, 50 (3) 1700681; 10.1183/13993003.00681-2017
Treating breathlessness via the brain: changes in brain activity over a course of pulmonary rehabilitation Mari Herigstad, Olivia K. Faull, Anja Hayen, Eleanor Evans, F. Maxine Hardinge, Katja Wiech, Kyle T.S. Pattinson Eur Respir J, 50 (3) 1701029; 10.1183/13993003.01029-2017
Primary ciliary dyskinesia ciliated airway cells show increased susceptibility to Haemophilus influenzae biofilm formation Woolf T. Walker, Claire L. Jackson, Raymond N. Allan, Samuel A. Collins, Michael J. Kelso, Ardeshir Rineh, Nageshwar R. Yepuri, Ben Nicholas, Laurie Lau, David Johnston, Peter Lackie, Saul N. Faust, Jane S.A. Lucas, Luanne Hall-Stoodley Eur Respir J, 50 (3) 1700612; 10.1183/13993003.00612-2017
Evaluation of severity score-guided approaches to macrolide use in community-acquired pneumonia Aran Singanayagam, Stefano Aliberti, Catia Cillóniz, Antoni Torres, Francesco Blasi, James D. Chalmers Eur Respir J, 50 (3) 1602306; 10.1183/13993003.02306-2016
The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypes Rachel K. Putman, Gunnar Gudmundsson, Tetsuro Araki, Mizuki Nishino, Sigurdur Sigurdsson, Elías F. Gudmundsson, Gudny Eiríksdottír, Thor Aspelund, James C. Ross, Raúl San José Estépar, Ezra R. Miller, Yoshitake Yamada, Masahiro Yanagawa, Noriyuki Tomiyama, Lenore J. Launer, Tamara B. Harris, Souheil El-Chemaly, Benjamin A. Raby, Michael H. Cho, Ivan O. Rosas, George R. Washko, David A. Schwartz, Edwin K. Silverman, Vilmundur Gudnason, Hiroto Hatabu, Gary M. Hunninghake Eur Respir J, 50 (3) 1700537; 10.1183/13993003.00537-2017
Bronchial hyperresponsiveness and obesity in middle age: insights from an Australian cohort John A. Burgess, Melanie C. Matheson, Fei Diao, David P. Johns, Bircan Erbas, Adrian J. Lowe, Lyle C. Gurrin, Caroline J. Lodge, Paul S. Thomas, Stephen Morrison, Bruce R. Thompson, Iain Feather, Jennifer L. Perret, Michael J. Abramson, Graham G. Giles, John L. Hopper, Shyamali C. Dharmage, Eugene H. Walters Eur Respir J, 50 (3) 1602181; 10.1183/13993003.02181-2016
The paradoxes of asthma management: time for a new approach? Paul M. O'Byrne, Christine Jenkins, Eric D. Bateman Eur Respir J, 50 (3) 1701103; 10.1183/13993003.01103-2017
Pain control in thoracic oncology Christine Peeters-Asdourian, Gilbert Massard, Paragi H. Rana, Paul Van Houtte, Andrew P. White, Bogdan Grigoriu, Dominique Lossignol, Mohammed Almalki, Jean Alexiou, Jean-Luc Engelholm, Jean-Paul Sculier Eur Respir J, 50 (3) 1700611; 10.1183/13993003.00611-2017
Mechanistic insight into the function of the microbiome in lung diseases Niki D.J. Ubags, Benjamin J. Marsland Eur Respir J, 50 (3) 1602467; 10.1183/13993003.02467-2016
Macrophage dysfunction in the pathogenesis and treatment of asthma Michael Fricker, Peter G. Gibson Eur Respir J, 50 (3) 1700196; 10.1183/13993003.00196-2017
Nitrogen back-diffusion during multiple-breath washout with 100% oxygen Leanna Sullivan, Erick Forno, Knud Pedersen, Jørgen G. Nielsen, Daniel J. Weiner Eur Respir J, 50 (3) 1700679; 10.1183/13993003.00679-2017
Are indexed values better for defining exercise pulmonary hypertension? Jason Weatherald, Athénaïs Boucly, Edmund Lau, Laurent Godinas, Laurent Savale, Xavier Jaïs, David Montani, Olivier Sitbon, Gérald Simonneau, Marc Humbert, Denis Chemla, Philippe Hervé Eur Respir J, 50 (3) 1700240; 10.1183/13993003.00240-2017
Inhaled budesonide does not prevent acute mountain sickness after rapid ascent to 4559 m Marc Moritz Berger, Franziska Macholz, Mahdi Sareban, Peter Schmidt, Sebastian Fried, Daniel Dankl, Josef Niebauer, Peter Bärtsch, Heimo Mairbäurl Eur Respir J, 50 (3) 1700982; 10.1183/13993003.00982-2017
Three years of experience with a novel “virtual” pneumonia follow-up clinic Christopher R. Wilcox, Jamie V. Krishnan, Claire Duffus, Ben G. Marshall Eur Respir J, 50 (3) 1700703; 10.1183/13993003.00703-2017
Impact of alpha 1-antitrypsin deficiency and prior augmentation therapy on patients' survival after lung transplantation Anton Conrad, Sabina Janciauskiene, Thomas Köhnlein, Jan Fuge, Philipp Ivanyi, Igor Tudorache, Jens Gottlieb, Tobias Welte, Thomas Fuehner Eur Respir J, 50 (3) 1700962; 10.1183/13993003.00962-2017
Neither genotyping nor contact tracing allow correct understanding of multidrug-resistant tuberculosis transmission Arthur Fournier, Christine Bernard, Wladimir Sougakoff, Sylvie Quelet, Fadi Antoun, Cécile Charlois-Ou, Isabelle Dormant, Marie-Odile Dufour, Nora Hocine, Vincent Jarlier, Nicolas Veziris Eur Respir J, 50 (3) 1700891; 10.1183/13993003.00891-2017
Do community demographics, environmental characteristics and access to care affect risks of developing ACOS and mortality in people with asthma? Teresa To, Jingqin Zhu, Christopher Carlsten, Kristian Larsen, Kandace Ryckman, Laura Y. Feldman, Eric Crighton, M. Diane Lougheed, Christopher Licskai, Paul J. Villeneuve, Yushan Su, Mohsen Sadatsafavi, Andrea Gershon Eur Respir J, 50 (3) 1700644; 10.1183/13993003.00644-2017
Work productivity loss in mild to moderate COPD: lessons learned from the CanCOLD study Riany de Sousa Sena, Sara Ahmed, Wan C. Tan, Pei Z. Li, Laura Labonté, Shawn D. Aaron, Andrea Benedetti, Kenneth R. Chapman, B. Walker, J. Mark Fitzgerald, Paul Hernandez, François Maltais, Darcy D. Marciniuk, Denis E. O'Donnell, Don D. Sin, Jean Bourbeau Eur Respir J, 50 (3) 1701154; 10.1183/13993003.01154-2017
Overdosing on immediate-release morphine solution has predictable adverse effects David C. Currow, Magnus Ekström, Miriam J. Johnson Eur Respir J, 50 (3) 1701091; 10.1183/13993003.01091-2017
Predictable adverse events such as respiratory depression highlight the need for caution when prescribing morphine for refractory breathlessness Natasha Smallwood, John Politis, Brian Le Eur Respir J, 50 (3) 1701357; 10.1183/13993003.01357-2017
Bosutinib-related pneumonitis Etienne-Marie Jutant, Véronique Meignin, David Montani, Abdellatif Tazi, Philippe Rousselot, Anne Bergeron Eur Respir J, 50 (3) 1700930; 10.1183/13993003.00930-2017
ERJ September Podcast: The hidden burden of severe asthma Eur Respir J, 50 (3) 17E5003; 10.1183/13993003.E5003-2017
Can epidemiological studies determine the productivity-related burden of COPD? Sanja Stanojevic Eur Respir J, 50 (3) 1701515; 10.1183/13993003.01515-2017
Dissecting COPD exacerbations: time to rethink our definition Bartolome R. Celli Eur Respir J, 50 (3) 1701432; 10.1183/13993003.01432-2017
10 years since TORCH: shining a new light on the risks of inhaled corticosteroids in COPD James D. Chalmers, Holly R. Keir Eur Respir J, 50 (3) 1701582; 10.1183/13993003.01582-2017
Mycobacterium avium complex infection: phenotypes and outcomes Michael R. Loebinger Eur Respir J, 50 (3) 1701380; 10.1183/13993003.01380-2017
Protecting young children from influenza Peter J. Gill, Kay Wang Eur Respir J, 50 (3) 1701550; 10.1183/13993003.01550-2017
An invisible disease: severe asthma is more than just “bad asthma” Sally E. Wenzel, Sheila Brillhart, Kristin Nowack Eur Respir J, 50 (3) 1701109; 10.1183/13993003.01109-2017
New drug targets for chronic cough: research you can literally sink your teeth into! Caroline J. Jolley, Surinder S. Birring Eur Respir J, 50 (3) 1701571; 10.1183/13993003.01571-2017
Two valves in the pharynx Shiroh Isono Eur Respir J, 50 (3) 1701496; 10.1183/13993003.01496-2017
The Art of Breathing: Distribution Gary P. Anderson Eur Respir J, 50 (3) 1705003; 10.1183/13993003.05003-2017
Unemployment in chronic airflow obstruction around the world: results from the BOLD study Rune Grønseth, Marta Erdal, Wan C. Tan, Daniel O. Obaseki, Andre F.S. Amaral, Thorarinn Gislason, Sanjay K. Juvekar, Parvaiz A. Koul, Michael Studnicka, Sundeep Salvi, Peter Burney, A. Sonia Buist, William M. Vollmer, Ane Johannessen Eur Respir J, 50 (3) 1700499; 10.1183/13993003.00499-2017
Multi-level differential network analysis of COPD exacerbations Guillaume Noell, Borja G. Cosío, Rosa Faner, Eduard Monsó, German Peces-Barba, Alfredo de Diego, Cristobal Esteban, Joaquim Gea, Robert Rodriguez-Roisin, Marian Garcia-Nuñez, Francisco Pozo-Rodriguez, Susana G. Kalko, Alvar Agustí Eur Respir J, 50 (3) 1700075; 10.1183/13993003.00075-2017
The risk of mycobacterial infections associated with inhaled corticosteroid use Sarah K. Brode, Michael A. Campitelli, Jeffrey C. Kwong, Hong Lu, Alex Marchand-Austin, Andrea S. Gershon, Frances B. Jamieson, Theodore K. Marras Eur Respir J, 50 (3) 1700037; 10.1183/13993003.00037-2017
Outcomes of Mycobacterium avium complex lung disease based on clinical phenotype Won-Jung Koh, Seong Mi Moon, Su-Young Kim, Min-Ah Woo, Seonwoo Kim, Byung Woo Jhun, Hye Yun Park, Kyeongman Jeon, Hee Jae Huh, Chang-Seok Ki, Nam Yong Lee, Myung Jin Chung, Kyung Soo Lee, Sung Jae Shin, Charles L. Daley, Hojoong Kim, O Jung Kwon Eur Respir J, 50 (3) 1602503; 10.1183/13993003.02503-2016
Risk factors for admission to hospital with laboratory-confirmed influenza in young children: birth cohort study Pia Hardelid, Maximiliane Verfuerden, Jim McMenamin, Ruth Gilbert Eur Respir J, 50 (3) 1700489; 10.1183/13993003.00489-2017
“I have lost in every facet of my life”: the hidden burden of severe asthma Juliet M. Foster, Vanessa M. McDonald, Michael Guo, Helen K. Reddel Eur Respir J, 50 (3) 1700765; 10.1183/13993003.00765-2017
Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma Pieter-Paul Hekking, Matthew J. Loza, Stelios Pavlidis, Bertrand De Meulder, Diane Lefaudeux, Frederic Baribaud, Charles Auffray, Ariane H. Wagener, Paul Brinkman, René Lutter, Aruna T. Bansal, Ana R. Sousa, Stewart A. Bates, Ioannis Pandis, Louise J. Fleming, Dominick E. Shaw, Stephen J. Fowler, Yike Guo, Andrea Meiser, Kai Sun, Julie Corfield, Peter Howarth, Elisabeth H. Bel, Ian M. Adcock, Kian Fan Chung, Ratko Djukanovic, Peter J. Sterk Eur Respir J, 50 (3) 1602298; 10.1183/13993003.02298-2016
Targeting fatty acid amide hydrolase as a therapeutic strategy for antitussive therapy Michael A. Wortley, John J. Adcock, Eric D. Dubuis, Sarah A. Maher, Sara J. Bonvini, Isabelle Delescluse, Ross Kinloch, Gordon McMurray, Christelle Perros-Huguet, Marianthi Papakosta, Mark A. Birrell, Maria G. Belvisi Eur Respir J, 50 (3) 1700782; 10.1183/13993003.00782-2017
TRPA1 activation in a human sensory neuronal model: relevance to cough hypersensitivity? Rebecca Clarke, Kevin Monaghan, Imad About, Caoimhin S. Griffin, Gerard P. Sergeant, Ikhlas El Karim, J. Graham McGeown, S. Louise Cosby, Timothy M. Curtis, Lorcan P. McGarvey, Fionnuala T. Lundy Eur Respir J, 50 (3) 1700995; 10.1183/13993003.00995-2017
Predicting epiglottic collapse in patients with obstructive sleep apnoea Ali Azarbarzin, Melania Marques, Scott A. Sands, Sara Op de Beeck, Pedro R. Genta, Luigi Taranto-Montemurro, Camila M. de Melo, Ludovico Messineo, Olivier M. Vanderveken, David P. White, Andrew Wellman Eur Respir J, 50 (3) 1700345; 10.1183/13993003.00345-2017
Evaluation of criteria for exercise-induced pulmonary hypertension in patients with resting pulmonary hypertension Christopher J. Mullin, Steven Hsu, Kaushik Amancherla, Alison Wand, Parker Rhodes, Peter J. Leary, Monica Mukherjee, Rachel L. Damico, Todd M. Kolb, Stephen C. Mathai, Paul M. Hassoun, Ryan J. Tedford Eur Respir J, 50 (3) 1700784; 10.1183/13993003.00784-2017
Determinants of diaphragm thickening fraction during mechanical ventilation: an ancillary study of a randomised trial Emmanuel Vivier, Ferran Roche-Campo, Laurent Brochard, Armand Mekontso Dessap Eur Respir J, 50 (3) 1700783; 10.1183/13993003.00783-2017
Direct oral anticoagulants for the treatment of acute venous thromboembolism in patients with cancer: a meta-analysis of randomised controlled trials Matteo Nicola Dario Di Minno, Walter Ageno, Roberta Lupoli, Giulia Conte, Nick van Es, Harry R. Buller, Francesco Dentali Eur Respir J, 50 (3) 1701097; 10.1183/13993003.01097-2017
Which algorithm diagnoses invasive pulmonary aspergillosis best in ICU patients with COPD? Pierre Bulpa, Benoît Bihin, George Dimopoulos, Fabio S. Taccone, Anne-Marie Van den Abeele, Benoît Misset, Wouter Meersseman, Herbert Spapen, Teresa Cardoso, Pierre-Emmanuel Charles, Jordi Rello, Dirk Vogelaers, Stijn Blot Eur Respir J, 50 (3) 1700532; 10.1183/13993003.00532-2017
The independent association of overweight and obesity with breathlessness in adults: a cross-sectional, population-based study David C. Currow, Eleonora Dal Grande, Calvin Sidhu, Magnus Ekström, Miriam J. Johnson Eur Respir J, 50 (3) 1700558; 10.1183/13993003.00558-2017
The validation of the sit-to-stand test for COPD patients Arnaud Chambellan, Simon Nusinovici, Trija Vaidya, Pierre-Antoine Gourraud, Claire de Bisschop Eur Respir J, 50 (3) 1701203; 10.1183/13993003.01203-2017
The validation of the sit-to-stand test for COPD patients Sarah Crook, Milo A. Puhan, Anja Frei Eur Respir J, 50 (3) 1701506; 10.1183/13993003.01506-2017
Breathlessness despite optimal pathophysiological treatment: on the relevance of being chronic Capucine Morélot-Panzini, Dan Adler, Bernard Aguilaniu, Etienne Allard, Nathalie Bautin, Marc Beaumont, François-Xavier Blanc, Cécile Chenivesse, Laurence Dangers, Christophe Delclaux, Alexandre Demoule, Philippe Devillier, Alain Didier, Marjolaine Georges, Bruno Housset, Jean-Paul Janssens, Pierantonio Laveneziana, Louis Laviolette, Jean-François Muir, Gregory Ninot, Thierry Perez, Claudine Peiffer, Matthieu Schmidt, Thomas Similowski, Christian Straus, Camille Taillé, Sandra Van Den Broecke, Nicolas Roche Eur Respir J, 50 (3) 1701159; 10.1183/13993003.01159-2017
Breathlessness despite optimal pathophysiological treatment: on the relevance of being chronic Miriam J. Johnson, Janelle Yorke, John Hansen-Flaschen, Robert Lansing, Magnus Ekström, David C. Currow Eur Respir J, 50 (3) 1701297; 10.1183/13993003.01297-2017
Breathlessness despite optimal pathophysiological treatment: on the relevance of being chronic Peter M.A. Calverley Eur Respir J, 50 (3) 1701376; 10.1183/13993003.01376-2017