Research Seminars

About

Research Seminars gather a small number (20 to 100) of well-established and preferably young investigators to address scientific topics in depth and help break new ground. Research Seminars take place over two days in easy-to-reach European cities. They are scientific Seminars involving recently published work and research in progress. Participation is fully supported by the budget granted by the ERS.

IPF and cancer: wounds that do not heal

This seminar is to enhance efforts to improve the diagnostic and therapeutic strategies in IPF. Although the mortality rate of IPF is worse than for the majority of cancers, the recognition of IPF as a potentially fatal disease is not widespread, while the need for sustaining cancer research is accepted at any level of public opinion. Consistent with the cancer-like biology in IPF, the survival of IPF patients is poor, with a 5-year survival rate below 30%. The concept of IPF as a cancer-like disease may be helpful in identifying new pathogenic mechanisms that can be borrowed from cancer biology, potentially leading to different and more effective therapeutic approaches. This seminar gives participants an understanding of recent clinical and scientific concepts in lung fibrogenesis and oncogenesis.

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Similarities and links between IPF and cancer: biologic considerations C. Vancheri
Epigenetics in IPF and lung cancer K. Antoniou
Myofibroblast origin and behaviour in IPF B. Crestani
Angiogenesis in IPF and lung Cancer: a common pathway? M. Kolb
Oncogene induced senescence in cancer and IPF M. Chilosi
The role of stem cells in cancer T. Sethi
Epidemiology, clinical, imaging and histology aspects of lung cancer in IPF V. Poletti
Lung cancer and other ILDs G. Margaritopoulos
Endpoints in IPF and lung cancer trials: controversies and perspectives A. Wells
How to treat lung cancer in IPF patients J. Cadranel
Common therapeutic approaches in IPF and lung cancer M. Kreuter