S. Bonvini (London, United Kingdom), M. Wortley (London, United Kingdom)
Andrographolide inhibits the activation of NLRP3 inflammasome in patients with COPD
W. Xiao (Chengdu, China), J. Fu (Chengdu, China), S. Wang (Chengdu, China), Y. Wang (Chengdu, China), T. Miao (Chengdu, China), B. Mao (Chengdu, China)
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PUR1800 (RV1162), A novel narrow spectrum kinase inhibitor, but not Fluticasone, reduces TNFa-induced cytokine release by primary bronchial epithelial cells from healthy volunteers and COPD patients
A. Curran (Lexington, United States of America), C. Charron (London, United Kingdom), P. Russell (London, United Kingdom), D. Hava (Lexington, United States of America)
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AZD1402/PRS-060, an inhaled Anticalin® IL-4Ra antagonist, potently inhibits IL-4 induced functional effects in human whole blood, which can be employed translationally in clinical studies.
K. Pardali (Gothenburg, Sweden), F. Jiang (Gothenburg, Sweden), M. Fitzgerald (Boston, United States of America), G. Matschiner (Boston, United States of America), D. Keeling (Gothenburg, Sweden)
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The effects of fatty acid amide hydrolase and monoacylglycerol lipase inhibitors in lipopolysaccharide-induced airway inflammation and tracheal hyperreactivity in mice
R. Abohalaka (Ankara, Turkey), T. Bozkurt (Ankara, Turkey), S. Onder (Ankara, Turkey), I. Sahin-Erdemli (Ankara, Turkey)
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Effects of Nintedanib on the M1 and M2a polarization of human macrophages
N. Bellamri (Rennes, France), C. Morzadec (Rennes, France), V. Lecureur (Rennes, France), A. Joannes (Rennes, France), L. Wollin (Biberach an der Riss, Germany), S. Jouneau (Rennes, France), L. VERNHET (Rennes, France)
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Selective activation and targeting of autophagy in severe asthma.
K. Mcalinden (Sydney, Australia), A. Kota (Sydney, Australia), B. Oliver (Sydney, Australia), M. Haghi (Sydney, Australia), P. Sharma (Sydney, Australia)
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Effect of phosphodiesterase-4 inhibitor on the inflammation, oxidative damage and apoptosis in a saline lavage-induced model of acute lung injury
P. Kosutova (Martin, Slovakia), P. Mikolka (Martin, Slovakia), M. Kolomaznik (Martin, Slovakia), S. Balentova (Martin, Slovakia), A. Calkovska (Martin, Slovakia), D. Mokra (Martin, Slovakia)
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Mechanisms leading to the bronchoprotective effects of N-Acetylcysteine in human bronchi stimulated by lipopolysaccharide
L. Calzetta (Rome, Italy), P. Rogliani (Rome, Italy), F. Facciolo (Rome, Italy), B. Rinaldi (Naples, Italy), M. Cazzola (Rome, Italy), M. Matera (Naples, Italy)
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Differential anti-inflammatory effects of budesonide and a p38 MAPK inhibitor AZD7624 on COPD pulmonary cells
A. Higham (Manchester, United Kingdom), P. Karur (Manchester, United Kingdom), N. Jackson (Manchester, United Kingdom), D. Cunoosamy (Gothenburg, Sweden), P. Jansson (Gothenburg, Sweden), D. Singh (Manchester, United Kingdom)
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Clinically validated markers of the extracellular matrix remodelling are altered by potential anti-fibrotic compounds in a human lung fibrosis ex vivo model
D. Leeming (Herlev, Denmark), J. Sand (Herlev, Denmark), C. Hesse (Hannover, Germany), S. Konzok (Hannover, Germany), K. Sewald (Hannover, Germany), S. Rønnow (Herlev, Denmark), A. Braun (Hannover, Germany), M. Karsdal (Herlev, Denmark), S. Brockbank (Aachen, Germany), S. Cruwys (Aachen, Germany)
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Smooth-muscle-derived WNT-5A drives allergen-induced remodelling and Th2 type inflammation
T. Koopmans (Groningen, Netherlands), L. Hesse (Groningen, Netherlands), M. Nawijn (Groningen, Netherlands), M. Menzen (Groningen, Netherlands), R. Smits (Rotterdam, Netherlands), E. Bakker (Utrecht, Netherlands), J. Vonk (Groningen, Netherlands), M. Van Den Berge (Groningen, Netherlands), G. Koppelman (Groningen, Netherlands), V. Guryev (Groningen, Netherlands), R. Gosens (Groningen, Netherlands)
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Intrinsic tone in human airway smooth muscle increases subsequent contractile response
A. Cairncross (Perth, Australia), F. Sanai (Sydney, Australia), B. Mcparland (Sydney, Australia), G. King (Sydney, Australia), P. Mcfawn (Perth, Australia), J. Elliot (Perth, Australia), A. James (Perth, Australia), P. Noble (Perth, Australia)
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LPS and TNFa differentially increase intrapulmonary airway and artery contraction in mouse precision cut lung slices
E. Lamanna (Melbourne, Australia), C. Nold (Melbourne, Australia), J. Bourke (Melbourne, Australia)
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Free fatty acid receptors, FFAR1 and FFAR4, are novel bronchodilator targets in mouse and human precision-cut lung slices
J. Bourke (Melbourne, Australia), R. Angeles (Melbourne, Australia), C. Donovan (Melbourne, Australia), M. Lam (Melbourne, Australia), J. Micallef (Melbourne, Australia), B. Shimpukade (Odense, Denmark), T. Ulven (Copenhagen, Denmark), S. Royce (Melbourne, Australia)
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Comparative activity of ilmetropium iodide and other anticholinergic drugs.
T. Molostova (??????, Russian Federation), A. Chuchalin (??????, Russian Federation), Y. Kalinin (??????, Russian Federation), S. Skachilova (??????, Russian Federation), O. Proskurina (??????, Russian Federation)
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The anti-tussive effects of an inhaled LABA are maintained after chronic treatment
M. Wortley (London, United Kingdom), S. Bonvini (London, United Kingdom), P. Flajolet (London, United Kingdom), M. Belvisi (Gothenburg, Sweden), M. Birrell (London, United Kingdom)
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Allergen-induced BDNF expression and neuronal remodeling contributes to airway hyperresponsiveness
S. Nijboer (Groningen, Netherlands), A. De Groot (Groningen, Netherlands), E. VohlíDalová (Groningen, Netherlands), I. Bos (Groningen, Netherlands), Y. Prakash (Rochester, United States of America), R. Gosens (Groningen, Netherlands), L. Kistemaker (Groningen, Netherlands)
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Characterisation of TRPA1 activation on sensory nerves
X. Chen (London, United Kingdom), S. Bonvini (London, United Kingdom), E. Dubuis (London, United Kingdom), M. Birrell (London, United Kingdom), M. Belvisi (Gothenburg, Sweden)
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