International Congress Munich 2014


New studies into pulmonary proteases and antiproteases

Oral Presentation
Chairs: S. Meiners (Munich, Germany), L. Donnelly (London, United Kingdom)
A role for the WFDC protein, WAP2, in regulation of innate host defence in the lung
A. Glasgow, D. Small, A. Scott, D. McLean, N. Camper, U. Hamid, S. Hegarty, C. O'Kane, D. McAuley, F. Lundy, S. Elborn, S. Weldon, C. Taggart (Belfast, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Smoking alters alpha1-antitrypsin in alveolar macrophages possibly promoting misfolding
S. Baraldo, E. Bazzan, C. Radu, G. Turato, B. Molena, S. Ortolan, R. Cazzuffi, N. Nannini, M. Schiavon, F. Calabrese, F. Rea, P. Simioni, M. Cosio, M. Saetta (Padova, Italy; Montreal, Canada)
Congress or journal article abstract
Congress or journal article abstract
Development of secretory leukocyte protease inhibitor (SLPI) variants resistant to degradation by neutrophil elastase
A. Glasgow, N. Camper, D. Quinn, S. Elborn, S. Weldon, C. Taggart (Belfast, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Neutrophil elastase-activated host defence peptide prodrugs kill pseudomonas aeruginosa in a cystic fibrosis lung milieu
E. Forde, H. Humphreys, C. Greene, D. Fitzgerald-Hughes, M. Devocelle (Dublin, Ireland)
Congress or journal article abstractSlide presentation
Congress or journal article abstractSlide presentation
Urokinase plasminogen activation receptor (uPAR) levels correlate with bronchial epithelial barrier integrity
M. Slater, D. Shaw, I. Sayers (Nottingham, United Kingdom)
Congress or journal article abstractSlide presentation
Congress or journal article abstractSlide presentation
Activation of MMP-9 in BAL is increased in COPD exacerbation independently of smoking, lung function, microbiology and treatment
E. Papakonstantinou, I. Klagas, G. Karakiulakis, S. Savic Prince, M. Roth, M. Tamm, D. Stolz (Basel, Switzerland; Thessaloniki, Greece)
Congress or journal article abstract
Congress or journal article abstract
ADAM9 is upregulated in human COPD lungs and in human and murine lung in response to cigarette smoke
F. Polverino, M. Laucho Contreras, M. Divo, V. Pinto-Plata, B. Celli, C. A. Owen (Boston, Albuquerque, United States Of America; Parma, Italy)
Congress or journal article abstract
Congress or journal article abstract
Cigarette smoke-induced iBALT mediates macrophage activation in a B cell-dependent manner in COPD
G. John-Schuster, K. Hager, T. Conlon, M. Irmler, J. Beckers, O. Eickelberg, A. O. Yildirim (Neuherberg, München, Germany)
Congress or journal article abstract
Congress or journal article abstract