International Congress Munich 2014


Allergy and asthma: novel findings based on human cell biology

Thematic Poster Session
Chairs: H.J. Hoffmann (Aarhus, Denmark), J. Erjefalt (Lund, Sweden), C. Von Garnier (Bern, Switzerland), S. Siddiqui (Leicester, United Kingdom)
Investigating airway HMGB1 redox state in health and asthma
L. Di Candia, E. Venereau, J. R. A. Challiss, R. Saunders, M. E. Bianchi, C. E. Brightling (Leicester, United Kingdom; Milano, Italy)
Congress or journal article abstract
Congress or journal article abstract
Expression of Olig2 in terminally differentiated eosinophils among leukocytes
S. M. Hwang, J. H. Kang, I. Y. Chung (Ansan, Republic Of Korea)
Congress or journal article abstract
Congress or journal article abstract
Proteolytic activity present in house-dust-mite extracts degrades ENA-78/CXCL5 and reduces neutrophil migration
L. Keglowich, M. Tamm, N. Miglino, P. Borger (Basel, Switzerland)
Congress or journal article abstract
Congress or journal article abstract
Preclinical evaluation of GSK2245035, a potent and selective toll-like receptor 7 (TLR7) agonist
D. Quint, J. Hessey, D. Coe, F. Priest, A. Hillegas, D. Dalmas Wilk, M. Price, C. Edwards, K. Biggadike (Stevenage, Ware, United Kingdom; Upper Merion, United States Of America)
Congress or journal article abstract
Congress or journal article abstract
Eosinophil peroxidase induces expression of cholinergic genes via cell surface neural interactions
N. Akasheh, M. T. Walsh, R. Costello (Dublin, Ireland)
Congress or journal article abstract
Congress or journal article abstract
Anti-inflammatory effects of the novel PDE4 inhibitor CHF6001 on virus inducible cytokines
M. Edwards, F. Facchinetti, M. Civelli, G. Villetti, S. Johnston (London, United Kingdom; Parma, Italy)
Congress or journal article abstract
Congress or journal article abstract
The results of the immunomorphological study of the placenta in women with asthma
Y. R. Dymarskaya, O. V. Lavrova, L. B. Zubzhitskaya, E. A. Shapovalova (Saint-Petersburg, Russian Federation)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Serum IL-10 and IL-17 are not related to the efficacy of allergen specific immunotherapy in asthma
I. Agache, M. Anghel, C. Ciobanu, L. Rogozea (Brasov, Romania)
Congress or journal article abstract
Congress or journal article abstract
QAV680, cetirizine and their combination reduce nasal symptoms in patients with intermittent allergic rhinitis in an environmental exposure chamber
V. J. Erpenbeck, A. M. Salapatek, P. Patel, D. Carew, G. Dubois, S. Perry, M. Larbig (Basel, Switzerland; Toronto, Canada; Horsham, West Sussex, United Kingdom)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
The monocyte-dependent immune response to bacterial infections is systemically suppressed in COPD
J. Knobloch, S. Panek, S. Yanik, S. Körber, P. Bürger, D. Jungck, M. Peters, A. Koch (Bochum, Germany)
Congress or journal article abstract
Congress or journal article abstract
Safety, tolerability and pharmacokinetics of QAV680, an oral CRTh2 antagonist, in healthy subjects
V. J. Erpenbeck, R. Fuhr, G. Dubois, S. Perry (Basel, Switzerland; Berlin, Germany; Horsham, West Sussex, United Kingdom)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Characterization QAW039 and QAV680, two novel, potent and selective CRTh2 antagonists
L. Willard, Z. Brown, C. Owen, G. Dubois (Horsham, West Sussex, United Kingdom)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Safety, tolerability and pharmacokinetics of an oral competitive reversible CRTh2 antagonist, QAW039, in healthy subjects
V. J. Erpenbeck, E. Vets, L. Gheyle, W. Osuntokun, M. Larbig, S. Neelakantham, G. Dubois, S. Perry (Basel, Switzerland; Antwerp, Belgium; Horsham, United Kingdom; Hyderabad, India)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
QAW039, a slowly dissociating CRTh2 antagonist with potential for improved clinical efficacy
D. Sykes, M. Bradley, D. Riddy, L. Willard, E. Powell-Herlaar, D. Sandham, S. Watson, C. Bauer, G. Dubois, S. Charlton (Horsham, West Sussex, United Kingdom; Basel, Switzerland)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Efficacy and safety of 10 day treatment with the CRTh2 antagonist QAV680 evaluated in patients with allergic rhinitis in an environmental exposure chamber
V. J. Erpenbeck, A. M. Salapatek, P. Patel, J. Sanni, G. Dubois, P. Zhou, S. Perry, M. Larbig (Basel, Switzerland; Toronto, Canada; Horsham, West Sussex, United Kingdom)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Lower values of VEGF in the endometrial lining are a possible cause of reduced fertility in asthmatic patients
E. Juul Gade, S. Francis Thomsen, S. Lindenberg, N. Macklon, V. Backer (Copenhagen, Denmark; Southhampton, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
The effect of a helicobacter pylori lysate on the tolerant state of human monocyte derived dendritic cells
Y. van Wijck, A. van der Ham, L. Hussaarts, M. Yazdanbakhsh, P. Hiemstra, A. Müller, H. Smits, C. Taube (Leiden, Netherlands; Zürich, Switzerland)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Neutrophil extracellular traps formation and degradation rate during autoimmunity - preliminary results
M. Pruchniak, M. Arazna, U. Demkow (Warsaw, Poland)
Congress or journal article abstract
Congress or journal article abstract
Migration of human monocytes is stimulated by Jagged-1 and DLL-4 via the notch pathway
K. Watzinger, S. Desole, C. M. Kaehler (Innsbruck, Austria)
Congress or journal article abstract
Congress or journal article abstract
Polymorphisms of the vitamin D-binding protein (DBP) gene in Japanese patients with aspirin-exacerbated respiratory disease (AERD)
K. Kohyama, A. Kohyama, S. Abe, J. Morioka, K. Kodaira, K. Nakano, R. Souma, H. Satoh, N. Fueki, Y. Fukushima (Koshigaya, Ohra-machi, Japan)
Congress or journal article abstract
Congress or journal article abstract