International Congress Munich 2014


Novel approaches and evidence for drug development in respiratory diseases

Poster Discussion
Chairs: I. Vachier (Montpellier, France), B. Oliver (Sydney, Australia)
Dissociation between clinical trial inclusion and exclusion criteria for trials in severe asthma and the reality of the patient population
T. Brown, H. Rupani, C. Barber, S. Elliot, K. Gove, L. Lau, L. Hewitt, E. Ray, E. Aitken, S. Kerley, R. Kurukulaaratchy, C. Grainge, R. Djukanovic, A. Chauhan, P. Howarth (Portsmouth, Southampton, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Gene set variation analysis of mRNA expression in bronchial biopsies from the U-BIOPRED asthma study
S. Pavlidis, A. Rowe, I. Adcock, K. Russell, I. Pandis, Y. K. Guo, B. DMeuldere, D. Lefaudeux, C. Auffray, R. Djukanovic, P. Howarth, F. Chung, M. Loza, N. Rao, F. Baribaud (High Wycombe, Buckinghamshire, London, Southampton, United Kingdom; Lyon, France; Springhouse, United States Of America)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Abediterol, a novel long-acting inhaled beta2-agonist, has a fast association rate and long residence time at human beta2 receptors
M. Miralpeix, M. Letosa, M. Aparici, C. Puig, A. Gavaldà, D. Vilella, I. Ramos (Barcelona, Spain)
Congress or journal article abstract
Congress or journal article abstract
Pharmacokinetics (PK), safety and tolerability of abediterol and mometasone furoate fixed- and free-dose combinations in healthy subjects
E. Jimenez, E. DeNoia, S. Ruiz, B. Seoane, E. Massana, G. De Miquel, C. Astbury (Barcelona, Spain; San Antonio, United States Of America)
Congress or journal article abstract
Congress or journal article abstract
Lung deposition analysis of two formulations of fluticasone/salmeterol HFA pMDI in stable asthma patients
J. De Backer, C. V. Holsbeke, W. Vos, S. Vinchurkar, J. Rebello, M. Mangale, W. De Backer (Kontich, Wilrijkstraat 10, 2650, Belgium; Mumbai, India)
Congress or journal article abstract
Congress or journal article abstract
Differential effects of budesonide and fluticasone propionate on bronchial epithelial barrier function
I. Heijink, M. Jonker, N. Ten Hacken, E. Telenga, D. Postma, M. Van den Berge (Groningen, Netherlands)
Congress or journal article abstract
Congress or journal article abstract
The anti-inflammatory effects of sulforaphane are not mediated by the Nrf2 pathway
A. Durham, E. Jazrawi, J. A. Rhodes, C. Williams, I. Kilty, P. Barnes, K. F. Chung, I. Adcock (London, United Kingdom; Cambridge, United States Of America)
Congress or journal article abstract
Congress or journal article abstract
Anti-inflammatory effects of targeted lung denervation in patients with COPD
L. Kistemaker, D. J. Slebos, H. Meurs, H. Kerstjens, R. Gosens (Groningen, Netherlands)
Congress or journal article abstract
Congress or journal article abstract
Long-lasting interaction study between RPL554 and glycopyrronium bromide on human isolated bronchi
L. Calzetta, M. Cazzola, C. Page, P. Rogliani, F. Facciolo, M. G. Matera (Rome, Naples, Italy; London, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Pharmacological activities of roflumilast N-oxide, dexamethasone and formoterol in human neutrophils from healthy non-smokers and COPD patients
J. Milara, J. Lluch, A. Serrano, J. Freire, M. Qian, M. Alonso-Galicia, C. Sanz, R. Guijarro, J. Cortijo (Valencia, Spain; Jersey City, United States Of America)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Effectively targeting small airways using controlled inhalation for peripheral corticosteroid deposition
S. Canisius, K. Nocker, G. Scheuch, T. Hofmann (Gemünden, Germany)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Interaction between RPL554 and glycopyrronium bromide in small human airways
L. Calzetta, M. Cazzola, C. Page, P. Rogliani, F. Facciolo, M. G. Matera (Rome, Naples, Italy; London, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Interaction between aclidinium bromide and formoterol fumarate in small human airways
M. Cazzola, L. Calzetta, C. P. Page, P. Rogliani, F. Facciolo, A. Gavaldà, M. G. Matera (Rome, Naples, Italy; London, United Kingdom; Barcelona, Spain)
Congress or journal article abstract
Congress or journal article abstract
Development of a lung slice methodology to study the mechanisms of lung uptake and lysosomal trapping
E. Bäckström, A. Lundqvist, P. Svanberg, E. Boger, P. Ewing, M. Hammarlund-Udenaes, M. Fridén (Uppsala, Mölndal, Sweden)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Development of a human COPD model-on-a-chip to mimic disease exacerbation (a small airway-on-a-chip model)
K. Hajipouran Benam, R. Villenave, C. Lucchesi, M. Mazur, G. Hamilton, D. Ingber (Boston, United States Of America)
Congress or journal article abstract
Congress or journal article abstract
Expression of CysLT2 receptors in asthmatic lung, and the roles in bronchoconstriction
T. Nabe, T. Sekioka, M. Kadode, M. Fujii, T. Abe, M. Horiba, S. Kohno, K. Kawabata (Osaka, Kyoto, Gifu, Japan)
Congress or journal article abstract
Congress or journal article abstract
miRNA-145 & SMAD3 expression in patients with COPD
L O’Leary, B. Tildy, I. Papazoglou, I.M. Adcock, K.F. Chung, M. Perry (London, United Kingdom)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Decametoxine efficiency in the treatment of infectious exacerbation of asthma
M. Gumeniuk, S. Panchuk (Kyiv, Ukraine)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster