Citations should be made in the following way: Authors. Title. Eur Respir J 2014; 44: Suppl. 58, abstract number.
Citations should be made in the following way: Authors. Title. Eur Respir J 2014; 44: Suppl. 58, abstract number.
Personalised exposure and gene environment interactions in chronic airway disease: the exposome and epigenome
Hot topicsChairs: S. Holgate (Southampton, United Kingdom), V. Schluenssen (Arhus, Denmark)
Aims: The audience will take away from this session an understanding of:
- The (im)possibility of using traditional exposure approaches to identify risk factors;
- The applicability of personalised exposure;
- The value of personalised exposure compared to traditional environmental risk factor assessment;
- The possibilities of using OMICS in exposure sciences;
- How plausible gene-environment interactions can strengthen causal inference in respiratory epidemiology;
- The concept of gene-environment interactions that underlie COPD; and,
- The role played by gene expression levels in addition to genotype in the onset of COPD.