International Congress Munich 2014


Animal models in respiratory drug development

Poster Discussion
Chairs: R. Gosens (Groningen, Netherlands), L. Stanciu (Cluj-Napoca, Romania)
Characterisation of a steroid-insensitive severe asthma model
P. Nath, A. Young, V. Russell (Harlow, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease
K. I. Tanaka, T. Mizushima (Tokyo, Japan)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Species comparison of interleukin-13 induced airway hyperreactivity as model for allergic asthma
O. Danov, S. M. Jimenez Delgado, H. Drake, O. Pfennig, C. Förster, A. Braun, K. Sewald (Hannover, Germany)
Congress or journal article abstract
Congress or journal article abstract
BmTI-A: A serine protease inhibitor attenuates hyperresponsiveness in an experimental model of chronic allergic inflammation in Balb/c mice
A. CorrêaFlorencio, F. M. Arantes-Costa, R. Santos de Almeida, S. S. S. Hamaguchi, S. D. Sasaki, M. A. Martins, I. F. L. C. Tibério, F. D. T. Q. S Lopes, E. A. Leick (São Paulo, Santo André, Brazil)
Congress or journal article abstract
Congress or journal article abstract
Effects of cyclosporin H on airway inflammatory responses induced by mitochondrial damage-associated molecular patterns
M. Li, X. Zhang, L. Jia, H. Long, Y. Shen, C. Pang, F. Wen (Chengdu, China)
Congress or journal article abstract
Congress or journal article abstract
Effect of the combination of doxofylline and montelukast on LPS-induced leukocyte migration to the lung
Y. Vasquez, C. Page (London, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
In vivo efficacy of CHF6001, an inhaled PDE4 inhibitor with a wide therapeutic window
G. Villetti, P. T. Bolzoni, F. Bassani, M. Bergamaschi, P. L. Caruso, L. Battipaglia, A. Sala, F. Facchinetti, C. Carnini, M. Civelli (Parma, Milan, Italy)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Acute markers of neutrophilic lung infiltration in the non-human primate LPS model
S. Jordan, E. Spridgen, V. Fisher, J. Hincks, T. Grasiewicz, K. Meecham (Cambridge, United Kingdom)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Combined loss of M2 and M3 muscarinic acetylcholine receptor (mAChR) function in mutant mice increases serotonin airway responsiveness (AR)
J. Fisher, S. Vincent, P. Wannas, J. Wess (Kingston, Canada; Bethesda, United States Of America)
Congress or journal article abstract
Congress or journal article abstract
cPLA2alpha inhibitor ASB14780 suppresses airway MMP-9 production and improves respiratory function in cigarette-smoke induced model
M. Terakawa, M. Goto, T. Tomoo, T. Katayama, Y. Hayashi, K. Nagahira (Kobe, Japan)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Synergistic effect of human tubal mesenchymal stem cell (htMSCs) and low level laser (LLL) therapy significantly reduces experimental COPD in mice
F. Greiffo, A. Brito, E. Silveira, G. Moraes, F. Cipriani, V. Neves, C. Czeresnia, P. Perin, M. Nisenbaum, M. Maluf, F. Aimbire, J. P. Peron, R. Vieira, A. P. Oliveira (São Paulo, Brazil)
Congress or journal article abstract
Congress or journal article abstract
Both intranasal and intraperitoneal administration of human tubal mesenchymal stem cells (htMSC) ameliorates experimental COPD model
J. P. Peron, G. Moraes, A. Brito, E. Silveira, B. Rodrigues Jr., R. Avelino, B. Franco, G. Rossi, M. Pellaty, M. Zats, L. Evangelista, S. Halpern, R. Vieira, A. P. Oliveira (São Paulo, Brazil)
Congress or journal article abstract
Congress or journal article abstract
Importance of surface cooling during targeted lung denervation for COPD
M. Mayse, P. Johnson, J. Hummel (Minneapolis, Chapel Hill, United States Of America)
Congress or journal article abstract
Congress or journal article abstract
A combination of thyme and ivy exerts potent anti-inflammatory and mucus-normalizing activity in vivo and inhibits 5-LO and PDE4
J. Seibel, C. Pergola, O. Werz, K. Wosikowski, M. D. Lehner, J. Haunschild (Neumarkt, Jena, Germany)
Congress or journal article abstract
Congress or journal article abstract
A molecule derived from mycobacterium tuberculosis Cpn60.1 (compound Y) inhibits lung inflammation induced by LPS in mice
Y. Vasquez, A. Lightfoot, C. Page (London, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Lipid derivatives of dopamine and respiration
D. Zajac, A. Stasinska, M. Pokorski (Warsaw, Poland)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Aminophylline increases ventilation and crural diaphragm contractility in awake canines
J. Jagers, B. Rothwell, P. Easton (Calgary, Canada)
Congress or journal article abstract
Congress or journal article abstract
N-acetylcysteine potentiates surfactant therapy for experimental meconium aspiration syndrome
J. Kopincova, P. Mikolka, D. Mokra, A. Calkovska (Martin, Slovakia)
Congress or journal article abstract
Congress or journal article abstract