ERS International Congress, Milan 2017

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Lung fibrosis: basic science

Thematic Poster
Chairs: U. Costabel (Essen, Germany), Z. Daniil (Larisa, Greece), E. Renzoni (London, United Kingdom), I. Strambu (Bucuresti 5, Romania)

Naftopidil, a selective a1 adrenoceptor antagonist, inhibits the growth of lung fibroblasts and attenuates bleomycin-induced lung fibrosis in mice H. Urushiyama (Tokyo, Japan)
Effect of NF-?B inhibitor IMD-1041 on BLM-induced pulmonary fibrosis in mice Y. Chen (Chongqing, China)
Nintedanib inhibits pro-fibrotic mediators from T cells with relevance to connective tissue disease-associated interstitial lung disease L. Wollin (Biberach an der Riß, Germany)
The expression of TLRs and TRP channel in pulmonary sensory neuron in bleomycin induced fibrosis model. S. Lee (Seoul, Republic of Korea)
Concentrations of IL4Ra and TNFa in bronchoalveolar lavage fluid can distinguish hypersensitivity pneumonitis from other fibrosing interstitial lung diseases M. Kolbeková (Praha, Czech Republic)
Therapeutic benefits of exosomes derived from mesenchymal stromal cells in bleomycin-induced pulmonary fibrosis in aged mice. M. Glassberg (Miami, United States of America)
Late Breaking Abstract - Pharmacokinetics (PK) of nintedanib with add-on pirfenidone in patients with idiopathic pulmonary fibrosis (IPF): results from INJOURNEY W. Wuyts (Rotselaar, Belgium)
Therapeutic pamrevlumab (FG-3019) is more effective than pirfenidone or nintedanib in a mouse radiation-induced lung fibrosis model K. Lipson (San Francisco, United States of America)
Correlation of Nintedanib efficacy on fibrotic lesion deposition and lung function within a rat IPF model R. Carrington (Huntingdon, United Kingdom)
PBI-4425, a novel first-in-class anti-inflammatory/anti-fibrotic compound, reduces pulmonary emphysema and cutaneous hyperplasia in tight-skin (Fbn-1) mouse L. Gagnon (Laval, QC, Canada)
Deterioration of regulatory B cells and activation of follicular helper T cells in idiopathic interstitial pneumonias patients Y. Asai (Sapporo, Japan)
A phenotypic cell-based extracellular matrix deposition assay for target validation and drug discovery M. Gerckens (München, Germany)
Rescue of mutant ABCA3 by small molecular correctors S. Kinting (München, Germany)
Spectrum of Diffuse parenchymal lung disease (DPLD)– Results from a regional referral center in Germany- F. Reichenberger (Gauting, Germany)
Prevalence of Latent Infection with Mycobacterium Tuberculosis in Interstitial Lung Diseases Using Interferon Gamma Release Assay B. Uysaler (izmir, Turkey)
Bile acid receptor mediates TGF-ß1-induced activation of lung fibroblasts X. Liu (Shanghai, China)
Development of an integrative approach to identify key molecular targets involved in bleomycin-induced pulmonary fibrosis in rats. V. Pitozzi (PARMA, Italy)
Ghrelin protects against bleomycin-induced pulmonary fibrosis in mice Y. Kyomoto (Osaka, Japan)
Pro-fibrotic biomarkers in ex vivo lung tissue slices: A species comparison C. Hesse (HANNOVER, Germany)
Whole Transcriptome Analysis of Bleomycin(BLM) Induced Pulmonary Fibrosis(PF) of Rhesus Using RNA-seq L. Liu (CHENGDU, China)