ERS International Congress, Madrid 2019

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Saturday, 28.09.2019
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More than 1,000 webcasts and slide presentations, 1,900 e-posters and 4,200 abstracts from the International Congress in Madrid and are now available.

 

Citations should be made in the following way: Authors. Title. Eur Respir J 2019; 54: Suppl. 63, abstract number.


New mechanistic insights into pulmonary fibrosis

Thematic Poster
Chairs: O. Burgy (Dijon, France), M. Platé (London, United Kingdom), L. Organ (Nottingham (Nottinghamshire), United Kingdom), S. Rolandsson Enes (Burlington, United States of America)
Neutrophil extracellular traps contribute to pulmonary fibrosis induced by bleomycin
M. Suzuki (Chiba, Japan), J. Ikari (Chiba, Japan), R. Anazawa (Chiba, Japan), N. Tanaka (Chiba, Japan), Y. Katsumata (Chiba, Japan), A. Shimada (Chiba, Japan), E. Suzuki (Chiba, Japan), K. Tatsumi (Chiba, Japan)
Congress or journal article abstract
Congress or journal article abstract
SP-C deficiency causes early alveolar de-recruitment resulting in a combination of air spaces over-distension and spontaneous fibrotic remodeling in aging lungs
K. Sehlmeyer (Hannover, Germany), J. Ruwisch (Hannover, Germany), M. Ochs (Berlin, Germany), L. Knudsen (Hannover, Germany), E. Lopez Rodriguez (Hannover, Germany)
Congress or journal article abstract
Congress or journal article abstract
Electroporation-mediated HGF gene transfer increases mesenchymal stem cell and decreases MMP24 levels in a bleomycin-induced lung injury model.
A. Gazdhar (Bern, Switzerland), K. Fytianos (Bern, Switzerland), S. Pantasis (Zurich, Switzerland), S. Mykoniati (Delemont, Switzerland), M. Bordoli (Zurich, Switzerland), F. Batty (St Gallen, Switzerland), K. Hostettler (Basel, Switzerland), T. Geiser (Bern, Switzerland)
Congress or journal article abstract
Congress or journal article abstract
Biological- and imaging biomarkers of edema and fibrosis in a rat model of drug-induced interstitial lung disease (DIILD)
I. Mahmutovic Persson (Lund, Sweden), H. Falk Håkansson (Lund, Sweden), A. Örbom (Lund, Sweden), P. Önnervik (Lund, Sweden), J. Persson (Lund, Sweden), K. Von Wachenfeldt (Lund, Sweden), L. E. Olsson (Lund, Sweden)
Congress or journal article abstract
Congress or journal article abstract
Use of Telemetry and Plethysmography to Assess Respiratory Function in Conscious Rats with Bleomycin-Induced Lung Fibrosis
M. Mcelroy (Edinburgh, United Kingdom), C. Lam (London, United Kingdom), I. Cranston (Edinburgh, United Kingdom), J. Baily (Edinburgh, United Kingdom), P. Aston (Guildford, United Kingdom), M. Nandi (london, United Kingdom), A. Milne (Edinburgh, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Quantitation of hydroxyproline in a mouse model of bleomycin-induced lung fibrosis: comparison with histological analysis
V. Bigatto (Verona, Italy), E. Manni (Verona, Italy), D. Pompilio (Verona, Italy), M. Brana' (Verona, Italy), A. Chalidou (Verona, Italy), J. Velden (Hamburg, Germany), M. Corsi (Verona, Italy), V. Russell (Verona, Italy), F. Andreetta (Verona, Italy)
Congress or journal article abstract
Congress or journal article abstract
Automated histological image analysis for the assessment of bleomycin-induced pulmonary fibrosis in rodents
S. Pontis (Parma , Italy), F. Bignami (Parma , Italy), D. Miglietta (Parma , Italy), V. Pitozzi (Parma , Italy), P. Caruso (Parma , Italy), M. Pittelli (Parma , Italy), M. Bonatti (Parma , Italy), G. Villetti (Parma , Italy), M. Civelli (Parma , Italy), M. Trevisani (Parma , Italy)
Congress or journal article abstract
Congress or journal article abstract
An orally available, highly selective 5-hydroxytryptamine 2B (5-HT2B) receptor antagonist ameliorating pulmonary and dermal fibrosis
C. Wenglén (Lund, Sweden), H. Arozenius (Lund, Sweden), L. Pettersson (Lund, Sweden), G. Ekstrom (Lund, Sweden)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Understanding of Pharmacokinetics and Exposure Drives use of Nintedanib as a Positive Control Reference Item in a Rat Model of Bleomycin-Induced Fibrosis
M. Mcelroy (Edinburgh, United Kingdom), J. Baily (Edinburgh, United Kingdom), O. Peris Serrano (Edinburgh, United Kingdom), A. Marsden (Edinburgh, United Kingdom), M. Briggs (Harlow, United Kingdom), I. Love (Edinburgh, United Kingdom), S. Madden (Edinburgh, United Kingdom), S. Gandi (Edinburgh, United Kingdom), M. Whitmarsh (Harlow, United Kingdom), A. Young (Harlow, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Fibroblast activation triggered by LPA results in matrix synthesis/fibrogenesis different from that of TGF-ß1
N. Gudmann (Herlev, Denmark), Y. Luo (Princeton, United States of America), J. Sand (Herlev, Denmark), G. Trujillo (Princeton, United States of America), B. Murphy (Princeton, United States of America), P. Cheng (Princeton, United States of America), M. Karsdal (Herlev, Denmark), M. Nielsen (Herlev, Denmark), D. Leeming (Herlev, Denmark), G. Jarai (Princeton, United States of America)
Congress or journal article abstract
Congress or journal article abstract
Hypoxia-inducible factor pathway activation promotes bone-type collagen cross-linking in Idiopathic Pulmonary Fibrosis
C. Brereton (Southampton, United Kingdom), L. Yao (Southampton, United Kingdom), J. Bell (Southampton, United Kingdom), F. Conforti (Southampton, United Kingdom), A. Alzetani (Southampton, United Kingdom), A. Fabre (Dublin , Ireland), B. Marshall (Southampton, United Kingdom), L. Richeldi (Rome, Italy), D. Davies (Southampton, United Kingdom), Y. Wang (Southampton, United Kingdom), M. Jones (Southampton, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Erythropoietin (EPO) attenuates the immunohistochemical expression of autophagy antibodies in bleomycin (BLM), induced pulmonary fibrosis (PF) in rats
D. Tsavlis (Thessaloniki, Greece), D. Anestakis (Thessaloniki, Greece), P. Konstantinidou (Thessaloniki, Greece), K. Symeonidou (Thessaloniki, Greece), D. Koutsonikolas (Thessaloniki, Greece), A. Tzoumaka (Thessaloniki, Greece), E. Spandou (Thessaloniki, Greece)
Congress or journal article abstract
Congress or journal article abstract
PAR-2 mediated interactions between mast cells and fibroblasts cause a switch in fibroblast morphology and cytokine profile
M. Bagher (Lund, Sweden), O. Rosmark (Lund, Sweden), L. Elowsson Rendin (Lund, Sweden), A. Nybom (Lund, Sweden), S. Wasserström (Lund, Sweden), C. Müller (Lund, Sweden), O. Hallgren (Lund, Sweden), L. Bjermer (Lund, Sweden), A. Larsson-Callerfelt (Lund, Sweden), G. Westergren-Thorsson (Lund, Sweden)
Congress or journal article abstract
Congress or journal article abstract
Deletion of Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) Aggravates Pulmonary Fibrosis
M. Kim (Seoul, Republic of Korea), J. Hong (Seoul, Republic of Korea), E. Kwak (Seoul, Republic of Korea), E. Kim (Seoul, Republic of Korea), K. Kim (Seoul, Republic of Korea), M. Sohn (Seoul, Republic of Korea)
Congress or journal article abstract
Congress or journal article abstract
Elevated serum S100A4 levels in patients with silicosis
G. lingli (Tangshan, China), H. Liu (Tangshan, China), X. Hao (Tangshan, China)
Congress or journal article abstract
Congress or journal article abstract
Investigating the role of AKAP13 on epithelial cell TGFß activation
L. Organ (Nottingham , United Kingdom), J. Porte (Nottingham , United Kingdom), A. John (Nottingham , United Kingdom), G. Jenkins (Nottingham , United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
The epigenetic modulator 5-aza-2’-deoxycytidine reduces the fibrotic response of human lung fibroblasts to TGFß1 in a novel, long term, 3D cell culture system.
M. Ward (Dublin, Ireland), D. Smart (Southampton, United Kingdom), J. Roberts (Southampton, United Kingdom), P. Monk (Southampton, United Kingdom), D. Davies (Southampton, United Kingdom), M. Jones (Southampton, United Kingdom), K. O'Reilly (Dublin, Ireland), J. Baugh (Dublin, Ireland)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Targeting the Hippo signaling pathway to enhance ex vivo lung epithelial tissue regeneration and maturation
D. Gorman (Boston, MA, United States of America), T. Wu (Boston, MA, United States of America), H. Ott (Boston, MA, United States of America), S. Gilpin (Boston, MA, United States of America)
Congress or journal article abstract
Congress or journal article abstract
Role of IL23 in the development of fibrotic interstitial lung disease
J. Lau (Rochester, United States of America), S. Wang (Rochester, United States of America), J. Davis (Rochester, United States of America), E. Matteson (Rochester, United States of America), R. Vassallo (Rochester, United States of America)
Congress or journal article abstract
Congress or journal article abstract