ERS International Congress, Madrid 2019

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Citations should be made in the following way: Authors. Title. Eur Respir J 2019; 54: Suppl. 63, abstract number.

Identification of new targets and therapeutic strategies for lung disease

Thematic Poster
Chairs: R. Gosens (Groningen, Netherlands), I. Mahmutovic Persson (Lund, Sweden), S. Hardy (Bruxelles, Belgium), A. van der Does (Leiden, Netherlands)

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Role of ASC oligomerization and NEK7-NLRP3 interaction in the pathogenesis of house dust mite-induced asthma Y. Lee (Jeonju, Republic of Korea), S. Kim (Jeonju, Republic of Korea), H. Park (Jeonju, Republic of Korea), J. Jeong (Jeonju, Republic of Korea), K. Park (Jeonju, Republic of Korea)
Bosutinib protects against pulmonary vascular leakage by improving endothelial cell-matrix adhesion L. Botros (Amsterdam, Netherlands), M. Pronk (Amsterdam, Netherlands), J. Juschten (Amsterdam, Netherlands), J. Liddle (Stevenage, United Kingdom), P. Tuinman (Amsterdam, Netherlands), S. Huveneers (Amsterdam, Netherlands), H. Bogaard (Amsterdam, Netherlands), V. Van Hinsbergh (Amsterdam, Netherlands), P. Hordijk (Amsterdam, Netherlands), J. Aman (Amsterdam, Netherlands)
Pharmacological induction of A20: Anti-inflammatory effects in paediatric asthma K. Mcconnell (Belfast, United Kingdom), G. Thillaiyampalam (Brisbane, Australia), A. Elbanna (Belfast, United Kingdom), A. Brown (Belfast, United Kingdom), M. Ennis (Belfast, United Kingdom), S. Zhang (Londonderry, United Kingdom), M. Shields (Belfast, United Kingdom), B. Schock (Belfast, United Kingdom)
Impact of Tacrolimus in the epithelial-mesenchymal transition in chronic lung allograft dysfonction M. Gracyasz (Strasbourg, France), K. Vallière (Strasbourg, France), A. El Habhab (Strasbourg, France), B. Renaud-Picard (Strasbourg, France), F. El-Ghazouani (Strasbourg, France), L. Kessler (Strasbourg, France), F. Toti (Strasbourg, France), R. Kessler (Strasbourg, France)
Altered mitochondrial function in proliferating airway smooth muscle cells C. Michaeloudes (London, United Kingdom), J. Frankenberg Garcia (London, United Kingdom), B. Xu (Shenzhen, China), X. Li (Shenzhen, China), C. Hui (Shenzhen, China), K. Chung (London, United Kingdom), P. Bhavsar (London, United Kingdom)
Effect of oral administration of echinochrome on lipopolysaccharide-induced lung injury in the immature Wistar rats M. Kuznetsova (Khabarovsk, Russian Federation), O. Lebed'Ko (Khabarovsk, Russian Federation), B. Ryzhavskii (Khabarovsk, Russian Federation), N. Mishchenko (Vladivostok, Russian Federation)
Effect of echinochrome on the respiratory burst of blood polymorphonuclear neutrophils in pediatric patients with interstitial lung disease (ILD): an in vitro study. M. Kuznetsova (Khabarovsk, Russian Federation), O. Lebed’Ko (Khabarovsk, Russian Federation), B. Ryzhavskii (Khabarovsk, Russian Federation), N. Mishchenko (Vladivostok, Russian Federation)
Up-regulation of paraoxonase 2 in human bronchial epitehlial cells D. Winnica (Aurora, United States of America), S. Sharma (Aurora, United States of America), L. Que (North Caroline, United States of America), S. Ye (Aurora, United States of America), V. Smith (Aurora, United States of America), C. Margaret (Aurora, United States of America), N. Perez (Aurora, United States of America), F. Holguin (Aurora, United States of America)
MiR-1165-3p downregulated in Th2 cells inhibits Th2 differentiation in allergic asthma by targeting PPM1A Z. Wang (Nanjing, China), M. Huang (Nanjing, China), N. Ji (Nanjing, China), M. Zhang (Nanjing, China)
Asthma and severe obesity: glucocorticoid sensitivity before and after bariatric surgery M. Bantulà Fonts (Barcelona, Spain), J. Roca-Ferrer (Barcelona, Spain), C. Picado (Barcelona, Spain), I. Bobolea (Barcelona, Spain), A. Valero (Barcelona, Spain), J. Mullol (Barcelona, Spain), J. Bartra (Barcelona, Spain), E. Arismendi (Barcelona, Spain)
Analysis of cytogenetic alterations in peripheral blood lymphocytes from asthmatic patients treated with oral corticosteroids A. Lintsov (St. Petersburg, Russian Federation), V. Trofimov (St. Petersburg, Russian Federation), A. Soliev (St. Petersburg, Russian Federation), B. Uslontsev (St. Petersburg, Russian Federation), P. Slizhov (St. Petersburg, Russian Federation), N. Pleskach (St. Petersburg, Russian Federation), I. Spivak (St. Petersburg, Russian Federation), V. Mikhelson (St. Petersburg, Russian Federation)
Members of the microRNA cluster 17-92 are disease specifically regulated in fibroblasts of idiopathic pulmonary fibrosis C. Lambers (Vienna , Austria), S. Blumer (Basel, Switzerland), L. Fang (Basel, Switzerland), K. Hötzenecker (Vienna, Austria), P. Jaksch (Vienna, Austria), M. Tamm (Basel, Switzerland), M. Roth (Basel, Switzerland)
Extracellular ATP is a danger signal activating P2X7 Receptor in a LPS mediated inflammation (ARDS/ALI) S. Cicko (Vienna, Austria), T. Köhler (Freiburg, Germany), M. Hossfeld (Freiburg, Germany), S. Schneider (Freiburg, Germany), A. Zech (Vienna, Austria), F. Di Virgillio (Ferrara, Italy), M. Idzko (Vienna, Austria)
Assessment of DNA repair synthesis in peripheral blood lymphocytes of asthmatic patients A. Lintsov (St.Petersburg, Russian Federation), A. Soliev (St.Petersburg, Russian Federation), V. Trofimov (St.Petersburg, Russian Federation), B. Uslontsev (St.Petersburg, Russian Federation), P. Slizhov (St.Petersburg, Russian Federation), N. Pleskach (St.Petersburg, Russian Federation), I. Spivak (St.Petersburg, Russian Federation), V. Mikhelson (St.Petersburg, Russian Federation)
LSC - 2019 - Post-transcriptional dysregulation as a novel mechanism underlying non-responsive severe asthma J. Rynne (London, United Kingdom), M. Plate (London, United Kingdom), R. Chambers (London, United Kingdom), P. Howarth (Southampton, United Kingdom), R. Martinez-Nunez (London, United Kingdom)
Cigarette smoke extract induces ER stress in human lung fibroblasts from COPD patients and healthy subjects M. Ryde (Lund, Sweden), R. Hillerström (Lund, Sweden), A. Malm (Lund, Sweden), G. Westergren-Thorsson (Lund, Sweden), L. Bjermer (Lund, Sweden), E. Tufvesson (Lund, Sweden)
NF-kB ACTIVATION IN CYSTIC FIBROSIS: THE DREAM OF A20 G. Momtazi (Belfast, United Kingdom), A. Elbanna (Belfast, United Kingdom), S. Finnegan (Belfast, United Kingdom), M. Héritier (Belfast, United Kingdom), L. Lavery (Belfast, United Kingdom), K. Mccollum (Belfast, United Kingdom), J. Naranjo (Madrid, Spain), B. Schock (Belfast, United Kingdom)
TNFAIP3/A20 expression in allergic asthma Y. Riffo-Vasquez (London, United Kingdom), V. Kanabar-Raivadera (London, United Kingdom), V. Corrigall (London, United Kingdom), C. Page (London, United Kingdom)
Mechanisms of acetylcholine-induced release of proinflammatory extracellular vesicles by endothelial cells and inhibitory effects of tiotropium T. Neri (Pisa, Italy), V. Scalise (Pisa, Italy), I. Passalacqua (Pisa, Italy), C. Sanguinetti (Pisa, Italy), S. Lombardi (Pisa, Italy), R. Pedrinelli (Pisa, Italy), P. Paggiaro (Pisa, Italy), A. Celi (Pisa, Italy)
The RNA binding protein HuR regulates the senescence-associated secretory phenotype under conditions of oxidative stress S. Hassibi (London, United Kingdom), J. Baker (London, United Kingdom), L. Donnelly (London, United Kingdom), P. Barnes (London, United Kingdom)