Annual Congress Berlin 2008

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Acute lung injury. Do we know what it is? A look at different models

Symposium
Chairs: S. Uhlig (Aachen, Germany), M. Takata (London, United Kingdom)
Aims: This symposium aims to compare established experimental models of acute lung injury (ALI). To that end, each speaker will apply a similar set of criteria to compare one particular model with the most frequently used model, the endotoxin model. This symposium will identify benefits and, in particular, underline shortcomings of currently used ALI models for the study of human disease. As particular attention is given to endotoxin models, one speaker speaks from the perspective of the animal model, while one acute respiratory distress syndrome (ARDS) clinician-scientist speaks from the human ALI/ARDS perspective. The session should provide valuable mechanistic insights into the disease processes of the models and of ALI/ARDS.

The endotoxin model in the year 2008 M. Takata (London, United Kingdom)
Mechanically induced lung injury J. Pugin (Geneve 14, Switzerland)
The zymosan model of acute lung injury and multiple organ failure S. Cuzzocrea (Messina, Italy)
Human acute lung injury versus the endotoxin model G. Downey (Denver, Co, United States of America)