C. Brightling (Leicester (Leicestershire), United Kingdom), V. Backer (Copenhagen, Denmark)
Late Breaking Abstract - Safety of ascending single and multiple doses of inhaled SIS, an isotonic aqueous solution of sodium hypochlorite, in healthy subjects
C. Burton (Copenhagen, Denmark), T. Balchen (Copenhagen, Denmark), L. Wilki-Kurtzhals (Copenhagen, Denmark), N. Sjögren (Stockholm, Sweden), T. Bjarnsholt (Copenhagen, Denmark), E. Jørgensen (Copenhagen, Denmark), D. Sonne (Copenhagen, Denmark)
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Late Breaking Abstract - ETD001: A long-acting inhaled ENaC blocker, is well tolerated in humans
P. Russell (Falmer, United Kingdom), K. Woodward (Falmer, United Kingdom), J. Charlwood (Falmer, United Kingdom), R. White (Loughborough, United Kingdom), D. Wilkes (London, United Kingdom), H. Danahay (Falmer, United Kingdom), D. Morris (Falmer, United Kingdom)
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Late Breaking Abstract - Metformin: A potential drug candidate to restore poor corticosteroid sensitivity in obese asthmatic patients
M. To (Saitama, Japan), N. Honda (Saitama, Japan), K. Haruki (Saitama, Japan), Y. To (Chiba, Japan)
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Late Breaking Abstract - Waning of biologic effect at end of dosing interval perceived by patients with severe asthma
J. Kroes (Leeuwarden, Netherlands), L. Van Hal (Groningen, Netherlands), L. Van Dijk (Groningen, Netherlands), S. Zielhuis (Leeuwarden, Netherlands), E. Van Roon (Leeuwarden, Netherlands), A. Ten Brinke (Leeuwarden, Netherlands), J. Kroes (Leeuwarden, Netherlands)
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Late Breaking Abstract - Impact of erdosteine on exacerbations in moderate COPD
P. Calverley (Liverpool (Merseyside), United Kingdom), A. Papi (Ferrara, Italy), C. Page (London, United Kingdom), P. Rogliani (Rome, Italy), R. Dal Negro (Verona, Italy), M. Cazzola (Rome, Italy), A. Cicero (Bologna, Italy), W. Wedzicha (Bologna, United Kingdom)
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Late Breaking Abstract - Understanding how azithromycin reduces asthma exacerbations and the underlying mechanisms of macrolides
L. Jurak (Woolloongabba, Australia), I. Yang (Brisbane, Australia), M. Hill (Brisbane, Australia), J. Simpson (Newcastle, Australia), J. Upham (Woolloongabba, Australia)
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Late Breaking Abstract - Achievement rate and predictive factors of the deep remission to biologics in severe asthma.
K. Oishi (Ube, Japan), K. Hamada (Ube, Japan), Y. Murata (Ube, Japan), Y. Yamaji (Ube, Japan), M. Asami (Ube, Japan), N. Edakuni (Ube, Japan), T. Hirano (Ube, Japan), K. Matsunaga (Ube, Japan)
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Late Breaking Abstract - Identification and characterisation of selective antagonists for TMEM16A(acd) isoform for the treatment of obstructive respiratory diseases.
p. saintot (verona, Italy), C. Carignani (verona, Italy), J. Phillips (Thousand Oaks, United States), C. Virginio (Verona, Italy)
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Late Breaking Abstract - A phase 3b, randomized controlled trial of gefapixant in recent-onset chronic cough
L. McGarvey (Belfast, Ireland), M. Sher (Largo, United States), Y. Grigorievich Shvarts (Saratov, Russian Federation), S. Lu (Rahway, United States), W. Wu (Rahway, United States), P. Xu (Rahway, United States), J. Schelfhout (Rahway, United States), C. La Rosa (Rahway, United States), A. Martin Nguyen (Rahway, United States), P. Reyfman (Rahway, United States), A. Sadaf Afzal (Rahway, United States), L. McGarvey (Belfast, United Kingdom)
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Late Breaking Abstract - Effects of anti-tryptase antibody in upper and lower airway of asthmatics
L. Henderson (South San Francisco, United States), K. Wong (South San Francisco, United States), V. Poon (South San Francisco, United States), G. Sperinde (South San Francisco, United States), R. Bauer (South San Francisco, United States), K. Yoshida (South San Francisco, United States), C. Chen (South San Francisco, United States), Q. Liu (South San Francisco, United States), Y. Chen (South San Francisco, United States), K. Long (South San Francisco, United States), P. Banerjee (South San Francisco, United States), S. Laing (South San Francisco, United States), N. Jones (South San Francisco, United States), H. Rhee (South San Francisco, United States), B. Leaker (London, United Kingdom), D. Singh (Manchester, United Kingdom), P. Bradding (Leicester, United Kingdom)
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Late Breaking Abstract - The antiasthmatic activity of Rho-kinase inhibitor hydroxyfasudil in the settings of experimentally induced allergic airway inflammation
S. Franova (Martin, Slovakia), M. Molitorisova (Martin, Slovakia), L. Kalmanova (Martin, Slovakia), J. Palencarova (Martin, Slovakia), M. Sutovska (Martin, Slovakia)
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Late Breaking Abstract - Implications of treatable traits and treatment choices on exacerbation risk in moderate-severe asthma
A. Yorgancioglu (Manisa, Turkey), I. Pavord (Oxford, United Kingdom), G. Brusselle (Ghent, Belgium), P. Pitrez (Porto Alegre, Brazil), S. Oosterholt (London, United Kingdom), A. Pg (Singapore, Singapore), O. Della Pasqua (London, United Kingdom)
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Late Breaking Abstract - International, prospective study of mepolizumab in severe asthma: REALITI-A at 2yrs
C. Caruso (Rome, Italy), G. Canonica (Milan, Italy), M. Patel (Wishaw, United Kingdom), A. Smith (Wishaw, United Kingdom), M. Liu (Baltimore, United States), R. Alfonso-Cristancho (Collegeville, United States), R. Price (Stevenage, United Kingdom), R. Jakes (Brentford, United Kingdom), L. Demetriou (Stevenage, United Kingdom), A. Valero (Barcelona, Spain), C. Pilette (Brussels, Belgium), P. Howarth (Brentford, United Kingdom)
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Late Breaking Abstract - Asthma exacerbation rate reduction with benralizumab in an integrated analysis of the real-world XALOC-1 study
D. Jackson (London, United Kingdom), G. Pelaia (Catanzaro, Italy), A. Padilla-Galo (Marbella, Málaga, Spain), M. Watt (London, United Kingdom), S. Kayaniyil (Toronto, Canada), S. Boarino (Milan, Italy), J. Tena (Spain, Spain), V. Shih (Gaithersburg, MD, United States), T. Tran (Gaithersburg, MD, United States), D. Arbetter (Boston, MA, United States), D. Cohen (Gaithersburg, MD, United States), R. Katial (Denver, CO, United States), J. Kwiatek (Gaithersburg, MD, United States), A. Shavit (Wedel, Germany), B. Emmanuel (Gaithersburg, MD, United States), P. Nair (Hamilton/Montreal, Canada)
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Late Breaking Abstract - KCa3.1 inhibition possesses complex anti-asthmatic effect in a guinea pig model of chronic asthma.
m. šutovská (Martin, Slovakia), J. Mažerik (Martin, Slovakia), S. Franová (Martin, Slovakia)
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Late Breaking Abstract - Early response and remission with benralizumab in patients with severe asthma and chronic rhinosinusitis with nasal polyposis (CRSwNP) in the prospective real-world ImPROve Asthma study
S. Korn (Mainz, Germany), H. Watz (Grosshansdorf, Germany), B. Emmanuel (Gaithersburg, United States), T. Plate (Hamburg, Germany), M. Saathoff (Gießen, Germany), A. Shavit (Cambridge, United Kingdom), T. Grund (Hamburg, Germany), M. Lommatzsch (Rostock, Germany)
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Late Breaking Abstract - Gender differences in gene polymorphisms are linked to up-reguated leukotriene pathway in asthma
D. Mirra (Caserta, Italy), R. Esposito (Caserta, Italy), G. Spaziano (Caserta, Italy), E. Cione (Rende, Cosenza, Italy), L. Gallelli (Catanzaro, Italy), F. Roviezzo (Napoli, Italy), F. Polverino (Houston, United States), B. D'Agostino (Caserta, Italy)
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Late Breaking Abstract - Cognitive impairment is common in patients with severe astma that are commenced on a biological treatment
C. Bernhoff (Copenhagen, Denmark), A. Jespersen (Copenhagen, Denmark), N. Dyhre-Petersen (Copenhagen, Denmark), D. Klein (Copenhagen, Denmark), K. Miskowiak (Copenhagen NV, Denmark), C. Porsbjerg (Copenhagen NV, Denmark)
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Late Breaking Abstract - The PARP14 inhibitor RBN-3143 suppresses lung inflammation in preclinical models
M. Niepel (Cambridge, United States), M. Vasbinder (Cambridge, United States), J. Molina (Cambridge, United States), B. Gui (Cambridge, United States), K. Kunii (Cambridge, United States), D. Blackwell (Cambridge, United States), E. Mateer (Cambridge, United States), J. Mo (Cambridge, United States), C. Coutts (Cambridge, United States), N. Perl (Cambridge, United States), K. Kuplast-Barr (Cambridge, United States), W. Church (Cambridge, United States), C. Majer (Cambridge, United States), L. Schenkel (Cambridge, United States), K. Swinger (Cambridge, United States), R. Abo (Cambridge, United States), E. Bamberg (Cambridge, United States), Y. Ren (Cambridge, United States), L. Utley (Cambridge, United States), T. Wigle (Cambridge, United States), C. Reik (Cambridge, United States), A. Lu (Cambridge, United States), A. Cheung (Cambridge, United States), E. Minissale (Cambridge, United States), K. Mceachern (Cambridge, United States), V. Richon (Cambridge, United States), S. Parasuraman (Cambridge, United States), K. Kuntz (Cambridge, United States), H. Keilhack (Cambridge, United States)
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