L. Uller (Lund, Sweden), A. Higham (Manchester (Greater Manchester), United Kingdom)
Cysteinyl-maresin 3 inhibits IL-13 induced airway hyperreactivity through alternative activation of the CysLT1 receptor J. Säfholm (Stockholm, Sweden), W. Abma (Stockholm, Sweden), C. E. Wheelock (Stockholm, Sweden), S. Dahlén (Stockholm, Sweden), M. Adner (Stockholm, Sweden)
| |
Features of rhinovirus-induced exacerbation of HDM-challenged mice S. Tillgren (Lund, Sweden), S. Cerps (Lund, Sweden), M. Menzel (Lund, Sweden), I. Mahmutovic Persson (Lund, Sweden), J. Nieto Fontarigo (Lund, Sweden), H. Akbarshahi (Lund, Sweden), L. Uller (Lund, Sweden)
| |
The anti-inflammatory and antifibrotic effects of a novel, pan-phosphodiesterase inhibitor in murine model of allergic asthma K. Wójcik-Pszczola (Kraków, Poland), K. Pociecha (Kraków, Poland), E. Wyska (Kraków, Poland), G. Chlon-Rzepa (Kraków, Poland), H. Plutecka (Kraków, Poland), M. Zadrozna (Kraków, Poland), B. Nowak (Kraków, Poland), P. Koczurkiewicz-Adamczyk (Kraków, Poland), E. Pekala (Kraków, Poland), R. Gosens (Groningen, Netherlands)
| |
Inhaled NXP002 attenuates LPS-induced inflammatory and fibrotic mediator production in the rat lung B. Humphries (Aachen, Germany), M. Saunders (London, United Kingdom), S. Cruwys (Aachen, Germany), B. Humphries (Aachen, Germany)
| |
Anti-fibrotic effect and in vivo target engagement of Nintedanib administered by oral gavage or by a medicated diet in a bleomycin lung fibrosis model in the rat M. Trevisani (Parma, Italy), P. Caruso (Parma, Italy), V. Pitozzi (Parma, Italy), S. Pontis (Parma, Italy), M. Pittelli (Parma, Italy), M. Bonatti (Parma, Italy), G. Villetti (Parma, Italy), M. Civelli (Parma, Italy)
| |
The differential synergistic injurious effect of resistive breathing on pulmonary and extra-pulmonary lung injury D. Toumpanakis (Athens, Greece), K. Glynos (Athens, Greece), V. Vassilakopoulou (Athens, Greece), A. Chatzianastasiou (Athens, Greece), E. Mizi (Athens, Greece), M. Dettoraki (Athens, Greece), F. Perlikos (Athens, Greece), C. Magkou (Athens, Greece), A. Papapetropoulos (Athens, Greece), T. Vassilakopoulos (Athens, Greece)
| |
Sphingosine-1-phosphate signaling pathway drives female asthma susceptibility E. Granato (Naples(NA), Italy), I. Cerqua (Naples(NA), Italy), R. Sorrentino (Naples(NA), Italy), G. Ferraro (Naples(NA), Italy), M. Nanì (Naples(NA), Italy), A. Rossi (Naples(NA), Italy), G. Cirino (Naples(NA), Italy), F. Roviezzo (Naples(NA), Italy)
| |
The role of PPAR-? antagonism on losartan ameliorating effect on lung injury and systemic inflammation induced by LPS in mice M. Boskabady (Mashhad, Islamic Republic of Iran), V. Rouki (Mashhad, Islamic Republic of Iran), S. Saadat (Mashhad, Islamic Republic of Iran), A. Memarzia (Mashhad, Islamic Republic of Iran), H. Salmani (Mashhad, Islamic Republic of Iran), Z. Gholamnezhad (Mashhad, Islamic Republic of Iran), M. Hosseini (Mashhad, Islamic Republic of Iran)
| |
A novel chronic guinea pig model of COPD using LPS and poly(I:C) exposure M. De Looff (Groningen, Netherlands), V. Verschut (Groningen, Netherlands), M. Woest (Groningen, Netherlands), I. Gorter (Groningen, Netherlands), K. Belfor (Groningen, Netherlands), I. Bos (Groningen, Netherlands), M. De Jager (Groningen, Netherlands), R. Gosens (Groningen, Netherlands), G. Villetti (Parma, Italy), F. Facchinetti (Parma, Italy), L. Kistemaker (Groningen, Netherlands)
| |
Targeting the carboxypeptidase activity: a promising strategy for asthma treatment V. Allam (Uppsala, Sweden), S. Taha (Uppsala, Sweden), I. Waern (Uppsala, Sweden), F. Avilés (Barcerlona, Spain), L. Devel (Paris, France), G. Pejler (Uppsala, Sweden), S. Wernersson (Uppsala, Sweden)
| |
Extrafine triple therapy shows improved efficacy compared to ICS/LABA in a mouse model of asthma D. Miglietta (Parma (PR), Italy), A. Pisano (Parma (PR), Italy), A. Allen (Parma (PR), Italy), D. Fragni (Parma (PR), Italy), G. Federico (Parma (PR), Italy), F. Bignami (Parma (PR), Italy), E. Zambelli (Parma (PR), Italy), R. Zecchi (Florence (FI), Italy), F. Boscaro (Florence (FI), Italy), B. Pioselli (Parma (PR), Italy), V. Mileo (Parma (PR), Italy), M. Civelli (Parma (PR), Italy), G. Villetti (Parma (PR), Italy)
| |
In vitro and ex-vivo evaluation of anti-inflammatory and anti-fibrotic effects of NXP002 in rat and human cells and lung tissue S. Cruwys (Aachen, Germany), M. Saunders (London, United Kingdom), A. Riddell (London, United Kingdom), B. Humphries (Aachen, Germany)
| |
Association between dietary fibre, microbial metabolites and airway obstruction in COPD patients and murine models K. Budden (Newcastle, Australia), S. Rehman (Sydney, Australia), S. Shukla (Newcastle, Australia), K. Bowerman (Brisbane, Australia), C. Donovan (Sydney, Australia), H. Gomez (Newcastle, Australia), C. Alemao (Newcastle, Australia), L. Wood (Newcastle, Australia), P. Dennis (Brisbane, Australia), P. Hugenholtz (Brisbane, Australia), P. Wark (Newcastle, Australia), P. Hansbro (Sydney, Australia)
| |
LPS-challenged equine bronchi: evidence for IL-6 as a target against AHR L. Calzetta (Parma, Italy), E. Pistocchini (Rome, Italy), G. Cito (Rome, Italy), B. Ritondo (Rome, Italy), S. Verri (Rome, Italy), P. Rogliani (Rome, Italy)
| |
Effect of a nutraceutical drug in COPD condition: A pilot study of in vitro, in vivo and Clinical Trial B. Pattnaik (New Delhi, India), N. Bhatraju (New Delhi, India), S. Kashyap (New Delhi, India), U. Verma (New Delhi, India), K. Madan (New Delhi, India), R. Guleria (New Delhi, India), A. Agrawal (New Delhi, India), A. Mohan (New Delhi, India)
| |
Exogenous HSP70 regulates the expression of glucocorticoid receptor in a cell type-specific manner L. Zhou (Basel, Switzerland), L. Fang (Basel, Switzerland), M. Tamm (Basel, Switzerland), M. Roth (Basel, Switzerland), D. Stolz (Basel, Switzerland)
| |
Lung inhalation-on-chip: A triple co-culture cellular platform to predict toxicity of aerosolized toxicants A. Sengupta (Bern, Switzerland), W. Hassan (Bern, Switzerland), N. Roldan (Bern, Switzerland), J. Stucki (Bern, Switzerland), T. Krebs (Waldkirch, Germany), O. Wisser (Waldkirch, Germany), N. Hobi (Bern, Switzerland), O. Guenat (Bern, Switzerland)
| |
Phosphoinositide-3 kinase antagonism does not reverse steroid insensitivity in severe asthma A. Bhalla (Hamilton, Canada), K. Son (Hamilton, Canada), K. Radford (Hamilton, Canada), C. Huang (Hamilton, Canada), M. Kjarsgaard (Hamilton, Canada), M. Mukherjee (Hamilton, Canada), P. Nair (Hamilton, Canada)
| |
COPD pathogenesis is dependent on ferroptotic death of AT2 cells driven by pro-inflammatory Macrophages A. Jeridi (München, Germany), T. M Conlon (München, Germany), G. Günes Günsel (München, Germany), M. Novikova (München, Germany), S. Doll (München, Germany), N. J Lang (München, Germany), S. E. Verleden (Leuven, Belgium), M. Rehberg (München, Germany), T. Stöger (München, Germany), H. B. Schiller (München, Germany), M. Conrad (München, Germany), A. Yildirim (München, Germany), A. Yildirim (Neuherberg, Germany)
| |
Bronchorelaxant effect of beclomethasone dipropionate in an ex vivo model of COPD exacerbation P. Rogliani (Roma (RM), Italy), J. Ora (Roma (RM), Italy), F. Facciolo (Roma (RM), Italy), E. Melis (Roma (RM), Italy), L. Calzetta (Parma, Italy), L. Calzetta (Roma (RM), Italy)
| |