A. Sengupta (Bern, Switzerland), S. Pouwels (Zuidhorn, Netherlands)
Bleomycin-induced in vitro 3D spheroid model to emulate pulmonary fibrosis E. Saygili (Izmir , Turkey), U. Devamoglu (Izmir , Turkey), B. Goker-Bagca (Aydin, Turkey), O. Goksel (Izmir , Turkey), C. Biray-Avci (Izmir , Turkey), T. Goksel (Izmir , Turkey), Ö. Yesil-Celiktas (Izmir , Turkey)
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Reticular basement membrane proteins modulate basal airway epithelial attachment and barrier formation in asthmatic airways A. Hsieh (Vancouver, Canada), E. Osei (Kelowna, Canada), M. Fouadi (Vancouver, Canada), K. Usman (Vancouver, Canada), Y. Yang (Vancouver, Canada), T. Hackett (Vancouver, Canada)
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Late Breaking Abstract - An apical-out airway organoid model to study viral infections and assess antiviral drug effects G. Stroulios (Cambridge, United Kingdom), T. Brown (Vancouver, Canada), D. Kondro (Cambridge, United Kingdom), A. Dei (Cambridge, United Kingdom), A. Eaves (Vancouver, Canada), S. Louis (Vancouver, Canada), J. Hou (Beijing, China), W. Chang (Cambridge, United Kingdom), S. Simmini (Cambridge, United Kingdom)
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Aging Induces Stiffening of the Lung Extracellular Matrix M. Narciso (Barcelona, Spain), A. Ulldemolins (Barcelona, Spain), D. Navajas (Barcelona, Spain), R. Farre (Barcelona, Spain), N. Gavara (Barcelona, Spain), I. Almendros (Barcelona, Spain)
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Autosomal recessive mutations in TP73 cause a mucociliary clearance disorder and lissencphaly J. Wallmeier (Münster, Germany), D. Bracht (Münster, Germany), H. Alsaif (Rhyiad, United Arab Emirates), G. Dougherty (Münster, Germany), H. Olbrich (Münster, Germany), S. Cindric (Münster, Germany), M. Dzietko (Essen, Germany), C. Heyer (Bochum, Germany), N. Teig (Bochum, Germany), C. Thiels (Bochum, Germany), F. Alkuraya (Rhyiad, United Arab Emirates), C. Koerner-Rettberg (Wesel, Germany), H. Omran (Münster, Germany)
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An in vivo genetic screen of lung function candidate genes using tissue-specific RNAi in Drosophila melanogaster E. Szamek (Nottingham, United Kingdom), I. Sayers (Nottingham, United Kingdom), M. Georgiou (Nottingham, United Kingdom), Z. Markus (Nottingham, United Kingdom)
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Humanized Patient-derived xenograft models for developing personalized therapy against Small Cell Lung Cancer H. Rouhrazi (Izmir, Turkey), S. Erdem (Izmir, Turkey), V. Zafari (Izmir, Turkey), G. Esmailnia (Izmir, Turkey), R. Meuwissen (Izmir, Turkey)
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Airspace dilatation is present at birth and increases with age in mice with cystic-fibrosis like lung disease P. Anagnostopoulou (NICOSIA, Cyprus), S. Blaskovic (Bern, Switzerland), D. Schittny (Bern, Switzerland), E. Borisova (Bern, Switzerland), F. Kronig (Bern, Switzerland), S. Ganesh (Bern, Switzerland), Z. Zhou-Suckow (Heidelberg, Germany), M. Mall (Berlin, Germany), C. Schlepu¨tz (Villigen, Switzerland), M. Stampanoni (Zu¨rich, Switzerland), J. Schittny (Bern, Switzerland)
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Respiratory disease modeling using submerged differentiated airway epithelial cells G. Amatngalim (Utrecht, Netherlands), H. Raeven (Utrecht, Netherlands), L. Rodenburg (Utrecht, Netherlands), L. Oosterhoff (Utrecht, Netherlands), S. Smits (Utrecht, Netherlands), I. Van Der Windt (Utrecht, Netherlands), C. Van Der Ent (Utrecht, Netherlands), J. Beekman (Utrecht, Netherlands)
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An amplification-free, innovative, multiplex assay to quantify microRNAs in single cells from COPD patients V. Ho (London, United Kingdom), J. Baker (London, United Kingdom), K. Willison (London, United Kingdom), D. Klug (London, United Kingdom), P. Barnes (London, United Kingdom), L. Donnelly (London, United Kingdom)
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Novel strategies for genetic manipulation of human iPSC-derived organoid platforms I. Oglesby (Dublin, Ireland), C. De Santi (Dublin, Ireland), A. Schweikert (Dublin, Ireland), S. Cryan (Dublin , Ireland), K. Hurley (Dublin, Ireland)
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Development of a bronchial epithelium model innervated by sensory neurons from human induced pluripotent stem cells F. FOISSET (ILLKIRCH CEDEX, France), C. Lehalle (ILLKIRCH CEDEX, France), A. Nasri (Montpellier , France), C. Bourdais (Montpellier , France), I. Vachier (Montpellier , France), S. Assou (Montpellier , France), Q. Muller (Strasbourg , France), V. Flacher (Strasbourg , France), A. Bourdin (Montpellier , France), J. De Vos (Montpellier , France), N. Frossard (ILLKIRCH CEDEX, France)
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Prolonged 3D culture leads to telomere length attrition in induced pluripotent stem cell-derived type 2 alveolar epithelial cells A. Schweikert (Dublin, Ireland), M. Ozaki (Dublin, Ireland), I. Oglesby (Dublin, Ireland), K. Hurley (Dublin, Ireland)
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High through-put computerised image analysis for primary ciliary dyskinesia diagnostics C. Jackson (Southampton (Hampshire), United Kingdom), N. Pathmanathan (Southampton (Hampshire), United Kingdom), J. Coles (Southampton (Hampshire), United Kingdom), D. Chatelet (Southampton (Hampshire), United Kingdom), G. Fryatt (Southampton (Hampshire), United Kingdom), J. Lucas (Southampton (Hampshire), United Kingdom)
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Cross-talk between alveolar epithelial cells and pulmonary arterial endothelial cells modulates activity of the L-arginine–dimethylarginine–NO pathway in hypoxia. R. Böger (Hamburg, Germany), L. Schmidt-Hutten (Hamburg, Germany), F. Franke (Hamburg, Germany), M. Kastner (Hamburg, Germany), M. Reckordt (Hamburg, Germany), J. Hannemann (Hamburg, Germany)
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Defining spatial secretome and ciliome across multiciliated epithelia M. Chowdhury (Dhaka, Bangladesh), L. Bingle (Sheffield, United Kingdom), C. Bingle (Sheffield, United Kingdom)
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Defining the functions of PIERCE1 and C15ORF65 during ciliogenesis of HBEC3-KT cells M. Chowdhury (Dhaka, Bangladesh), P. Anujan (Sheffield, United Kingdom), L. Bingle (Sheffield, United Kingdom), C. Bingle (Sheffield, United Kingdom)
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Relating ciliary dysfunction to clinical phenotypes in COPD J. Tonkin (London, United Kingdom), A. Rogers (London, United Kingdom), C. Orton (London, United Kingdom), F. Conway (London, United Kingdom), B. Vijayakumar (London, United Kingdom), L. Chan (London, United Kingdom), A. Tana (London, United Kingdom), C. Caneja (London, United Kingdom), L. Avanzi (London, United Kingdom), R. Wawman (London, United Kingdom), A. Baikov (London, United Kingdom), P. Bhavsar (London, United Kingdom), P. Shah (London, United Kingdom)
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An artichoke-derived compound increase [Ca2+i by inhibiting Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) and activates airway ciliary beating in humans N. Todo (Kyoto, Japan), K. Noriyama (Kyoto, Japan), N. Tamiya (Kyoto, Japan), M. Shigeta (Kyoto, Japan), S. Nakamura (Kyoto, Japan), K. Takayama (Kyoto, Japan), E. Ashihara (Kyoto, Japan), S. Hosogi (Kyoto, Japan)
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Comparative secretome analysis of differentiated epithelial cells grown at the Air liquid interface (ALI) Z. Alharbi (SHEFFIELD, United Kingdom), L. Bingle (SHEFFIELD, United Kingdom), C. Bingle (Sheffield, United Kingdom)
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