G. Caramori (Ferrara, Italy), H.J. Hoffmann (Aarhus, Denmark)
LATE-BREAKING ABSTRACT: Inhibition of ATP-gated P2X3 channels by AF-219: An effective anti-tussive mechanism in chronic cough
R. Abdulqawi, R. Dockry, K. Holt, A. Woodcock, G. Layton, B. McCarthy, A. Ford, S. Jaclyn (Manchester, Canterbury, United Kingdom; San Mateo, United States Of America)
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LATE-BREAKING ABSTRACT: Inhaled mannitol for non-cystic fibrosis bronchiectasis: results of a 12 month, multi-centre, double-blind, controlled study.
D. Bilton, G. Tino, A. Barker, D. Chambers, A. De Soyza, L. Dupont, C. O'Dochartaigh, E. van Haren, L. Otero Vidal, T. Welte, H. Fox, J. Wu, B. Charlton (London, Newcastle-upon-Tyne, United Kingdom; Philadelphia, Portland, United States Of America; Brisbane, Sydney, Australia; Leuven, Belgium; Auckland, New Zealand; Heerlen, Netherlands; Partido de Vicente Lopez, Argentina; Hannover, Germany)
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LATE-BREAKING ABSTRACT: The critical role of interferon-gamma signaling in the respiratory immune response to influenza infection
D. M Kemeny, N. Prabhu, A. W Ho, K. H Wong, B. C. Chua, P. E Hutchinson, B. Sivasankar (Sinagpore, Singapore, Singapore)
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LATE-BREAKING ABSTRACT: GW870086: A potent anti-inflammatory glucocorticoid with a novel pharmacological profile
S. Farrow, I. Uings, M. Haase, D. Angell, K. leavens, J. Holt, J. matthews, K. biggadike, D. needham (Stevenage, United Kingdom)
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LATE-BREAKING ABSTRACT: Anti-inflammatory effect of a novel inhaled dual PDE3/4 inhibitor RPL554 in man, a unique “first-in-class” drug for the treatment of COPD & asthma
D. Singh, F. Reid, L. Franciosi, M. Walker, C. Page (Manchester, London, United Kingdom; Vancouver, Canada)
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LATE-BREAKING ABSTRACT: RV568, a narrow spectrum kinase inhibitor (NSKI), inhibits virus induced nasal interleukin-8 (IL8) in the human viral challenge model where healthy adult male volunteers were experimentally inoculated with live respiratory syncytial virus
L. Cass, K. Ito, C. Charron, P. Strong, C. Norton, A. Gilbert, R. Lambkin-Williams, A. Mann, G. Rapeport (London, Totnes, United Kingdom)
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LATE-BREAKING ABSTRACT: Safety, pharmacokinetic and pharmacodynamic profile of RV568, a narrow spectrum kinase inhibitor, following repeat inhaled dosing in COPD patients
P. Russell, L. Cass, K. Ito, C. Charron, P. Strong, G. Rapeport, D. Singh (London, Manchester, United Kingdom)
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LATE-BREAKING ABSTRACT: The histone-deacetylase-8 selective inhibitor PCI-34051 enhances IFN-λ production in vitro and reduces inflammation in mouse models of rhinoviral infection and rhinovirus-induced exacerbations of asthma in vivo
M. Bosnar, G. Ergovic, B. Hrvacic, K. Frka Boric, A. Paravic Radicevic, I. Glojnaric, V. Erakovic Haber (Zagreb, Croatia)
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