Lung Science Conference - Metabolic alterations in lung ageing and disease, Estoril 2020

The Lung Science Conference is at the forefront of basic and translational respiratory science and it is an essential event for budding respiratory researchers looking to boost their career.




Educational aims
  • To present the very best of international lung science research
  • To highlight new discoveries likely to impact on the future of respiratory medicine
  • To encourage debate and interaction between young postdoctoral scientists and established investigators
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Opening Lecture: Metabolic reprogramming in innate immunity and inflammation
Luke O’Neill (Dublin, Ireland)
 [+]  PDF journal article, handout or slides Metabolic profiling of severe asthma: implications for phenotyping and treatment
Craig Wheelock (Stockholm, Sweden)
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 [+]  PDF journal article, handout or slides Long non-coding RNA ADPGK-AS1 controls anti-tumor immunity in macrophages through metabolic modulation
Annika Karger (Bad Nauheim, Germany)
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Metabolic reprogramming of tumor associated macrophages and its impact on lung cancer progression
Rajkumar Savai (Bad Nauheim, Germany)
 [+]  PDF journal article, handout or slides Single Cell RNA-seq Reveals Zinc Metabolism Defect of Alveolar Type II Cells with Aging in IPF
Carol Liang (Los Angeles, USA)
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 [+]  PDF journal article, handout or slides Mitochondria-targeted H2S suppresses and reverses cigarette smoke-induced inflammasome activity and lung injury in experimental COPD
Matt Whiteman (Exeter, United Kingdom)
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Mitochondrial in airway smooth muscle as a driver of airway hyperresponsiveness in asthma
Thomas Trian (Bordeaux, France)
 [+]  PDF journal article, handout or slides Mitochondrial metabolism regulates cellular proteostasis
Thomas Meul (Munich, Germany)
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 [+]  PDF journal article, handout or slides Mitochondrial iron in the susceptibility, pathogenesis and progression of COPD
Suzanne Cloonan (Dublin, Ireland)
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 [+]  PDF journal article, handout or slides 10 Cigarette smoke exposure disrupts the molecular regulation of mitochondrial metabolism in human bronchial and alveolar epithelial cells
Christy B.M. Tulen (Maastricht, Netherlands)
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 [+]  PDF journal article, handout or slides Slide presentation 11 Senotherapies for chronic lung disease
Peter Barnes (London, United Kingdom)
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 [+]  PDF journal article, handout or slides 12 Air space distension precedes spontaneous fibrotic remodeling and impaired cholesterol metabolism in the absence of surfactant protein C
Elena Lopez Rodriguez (Berlin, Germany)
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13 A diabetic microenvironment accelerates vascular senescence
Reinhold Medina (Belfast, United Kingdom)
 [+]  PDF journal article, handout or slides PDF journal article, handout or slides 14 Respiratory muscle senescence during chronic lung disease and ageing
Joaquim Gea (Barcelona, Spain)
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 [+]  PDF journal article, handout or slides 15 Aging causes alveolar epithelial type II cell dysfunction in acute lung injury
Christina Brandenberger (Hannover, Germany)
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 [+]  PDF journal article, handout or slides 16 Versatile workflow for storage, characterization and celltype resolved transcriptional and epigenetic profiling of human lung samples
Renata Jurkowska (Heidelberg, Germany)
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17 An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics
Herbert Schiller (Munich, Germany)
 [+]  PDF journal article, handout or slides 18 Caspase-1 activation by cigarette smoke occurs via TLR4/TRIF/caspase-8 axis leading to metabolic alterations in human macrophages
Marco Buscetta (Palermo, Italy)
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 [+]  PDF journal article, handout or slides 19 The role of the COPD susceptibility gene FAM13A in barrier function and pro-inflammatory responses of human airway epithelial cells
Qing Chen (Groningen, Netherlands)
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 [+]  PDF journal article, handout or slides 20 Validation of AMP-activated protein kinase as a therapeutic target in bronchiectasis
Yan Hui Giam (Dundee, United Kingdom)
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 [+]  PDF journal article, handout or slides 21 Itaconate drives the resolution of pulmonary fibrosis
Patricia Ogger (London, United Kingdom)
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 [+]  PDF journal article, handout or slides 22 MiR-320d as a regulator of airway inflammation in COPD
Mirjam P. Roffel (Groningen, Netherlands)
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 [+]  PDF journal article, handout or slides Slide presentation 23 How to write a convincing research grant
Reinoud Gosens (Groningen, Netherlands)
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 [+]  PDF journal article, handout or slides Slide presentation 24 Obtaining a grant to organize an ERS Research Seminar
Niki Ubags (Epalinges, Switzerland)
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 [+]  PDF journal article, handout or slides Slide presentation 25 Your first personal research grant within the ERS fellowship programme
Louise Donnelly (London, United Kingdom)
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26 Funding possibilities from the European Union (EU)/European Research Council (ERC)
Nadia El Mjyad (Brussels, Belgium)
 [+]  PDF journal article, handout or slides 27 The mitochondrion revisited: an overview of its role in lung inflammation and lung ageing
Phil Hansbro (Sydney, Australia)
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 [+]  PDF journal article, handout or slides PDF journal article, handout or slides 28 Linking proteostasis to immune activation in the ageing lung
Silke Meiners (Munich, Germany)
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29 Protein oxidation as a driver of disease and gateway to novel therapies for lung fibrosis
Martina Korfei (Giessen, Germany)
 [+]  PDF journal article, handout or slides Slide presentation 30 Metabolic reprogramming by mesenchymal stem cells as a strategy for lung repair
Anna Krasnodembskaya (Belfast, United Kingdom)
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 [+]  PDF journal article, handout or slides 31 Nutritional modulation to correct metabolic alterations in chronic lung disease
Annemie Schols (Maastricht, Netherlands)
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32 The promise of mTOR signaling as a therapeutic target for IPF
Rachel Chambers (London, United Kingdom)
 [+]  PDF journal article, handout or slides 33 Poster session 1
Justine Devulder (London, United Kingdom); Iva Hlapcic (Zagreb, Croatia); Anne-Sophie Lamort (Munich, Germany); Xinhui Wu (Groningen, Netherlands); Roy R. Woldhuis (Sydney, Australia); Kirsty Mccallum (Paisley, United Kingdom); Anna Konishcheva (Moscow, Russian Fed.); Julia Frankenberg Garcia (London, United Kingdom); Siavash Mansouri (Bad Nauheim, Germany); Wojciech Langwinski (Poznan, Poland); Alfredo Urtubia (Logroño, Spain); Charalambos Michaeloudes (London, United Kingdom); Mirjam P. Roffel (Ghent, Belgium); Kseniia Suska (Dnipro, Ukraine); Vanessa De Sa (Sao Paulo, Brazil); Qianjiang Hu (Munich, Germany); Ieva Janulaityte (Kaunas, Lithuania); Johnatas Silva (Belfast, United Kingdom); Matthew Lawson (Southampton, United Kingdom); David Rowlands (Cambridge, MA, USA); Xinyuan Wang (Munich, Germany); Eva Delbrel (London, United Kingdom); Pauline Esteves (Bordeaux, France); Mahyar Aghapour (Braunschweig, Germany); Cristina Rodríguez (Barcelona/Girona, Spain); Margarida Cortez e Castro (Lisbon, Portugal); Jonathan R. Baker (London, United Kingdom)
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 [+]  PDF journal article, handout or slides 34 Poster session 2
Yue Su (Belfast, United Kingdom); Ying Wang (Leiden, Netherlands); Claudio Bussi (London, United Kingdom); Diana Santos Ribeiro (Brussels, Belgium); Arlene Glasgow (Dublin, Ireland); Serena Di Vincenzo (Palermo, Italy); Mario Pepe (München, Germany); Marcin Skrzypski (London, United Kingdom); Muriel Pichavant (Lille, France); Catherine Wrench (London, United Kingdom); Ilias Angelidis (Munich, Germany); Maunick Lefin Koloko Ngassie (Groningen, Netherlands); Elodie Picard (Lille, France); Sandra Casas Recasens (Barcelona, Spain); Itsaso Garcia Arcos (New York, USA); Gesa Albers (London, United Kingdom); Susana Seixas (Porto, Portugal); Rachele Invernizzi (London, United Kingdom); Hannelore Van Eeckhoutte (Ghent, Belgium); Niki Reynaert (Burlington, USA); Aina Martin (Palma de Mallorca, Spain); Felix Ritzmann (Homburg/Saarland, Germany); Mareike Lehmann (Munich, Germany); Delphine Guillotin (London, United Kingdom); Nuria Mendoza (Barcelona, Spain); Christoph H. Mayr (Munich, Germany); Ekaterina Legchenko (Cambridge, United Kingdom); Isabella Cattani-Cavalieri (Rio de Janeiro, Brazil); Alen Faiz (Ultimo, Australia); Irma Mahmutovic Persson (Malmö, Sweden)
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