ERS Lung Science Conferences & more

Repair and regeneration in chronic lung disease and lung cancer, Virtual 2021

The Lung Science Conference is at the forefront of basic and translational respiratory science and it is an essential event for budding respiratory researchers looking to boost their career.

Educational aims

  • To present the very best of international lung science research
  • To highlight new discoveries likely to impact on the future of respiratory medicine
  • To encourage debate and interaction between young postdoctoral scientists and established investigators

Welcome and Introduction
Reinoud Gosens (Groningen, Netherlands)
WebcastSlide presentation
WebcastSlide presentation
Opening Lecture: Is human pulmonary fibrosis simply lung regeneration without a blueprint?
Naftali Kaminski (New Haven, United States of America)
WebcastSlide presentationPDF journal article, handout or slides
WebcastSlide presentationPDF journal article, handout or slides
iPSC derived lung stem cells as tools to understand lung regeneration and disease
Killian Hurley (Co. Meath, Ireland)
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WebcastSlide presentationPDF journal article, handout or slides
The journey of stem cell differentiation during alveolar regeneration
Joo-Hyeon Lee (Cambridge, United Kingdom)
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WebcastSlide presentationPDF journal article, handout or slides
Macrophage plasticity in COPD
Joachim Schultze (Bonn, Germany)
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WebcastSlide presentationPDF journal article, handout or slides
Epithelial-mesenchymal interactions involving FGFs
Saverio Bellusci (Giessen, Germany)
WebcastSlide presentationPDF journal article, handout or slides
WebcastSlide presentationPDF journal article, handout or slides
The role of the microvascular niche in lung regeneration
Edward Morrisey (Philadelphia, United States of America)
WebcastSlide presentationPDF journal article, handout or slides
WebcastSlide presentationPDF journal article, handout or slides
Poster session 1 - Group A

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Poster session 1 - Group B

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Poster session 1 - Group C

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Poster session 1 - Group D

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Poster session 2 - Group E

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Poster session 2 - Group F

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Poster session 2 - Group G

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Poster session 2 - Group H

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Webcast
Early-Career delegates session - Introduction
Niki Ubags (Epalinges, Switzerland)
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WebcastSlide presentation
The use of Pre-prints to publish your science
Darcy Wagner (Lund, Sweden)
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WebcastSlide presentation
How to write a peer review
Pieter S. Hiemstra (Leiden, Netherlands)
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WebcastSlide presentation
How to make me like your paper (part 1)
Martin Kolb (Hamilton (ON), Canada)
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WebcastSlide presentation
How to make me like your paper (part 2)
Susanne Herold (Gießen, Germany)
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WebcastSlide presentation
Early-Career delegates session - Panel discussion

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Webcast
Tobacco smoking and somatic mutations in human bronchial epithelium
Sam Janes (London, United Kingdom)
WebcastSlide presentationPDF journal article, handout or slides
WebcastSlide presentationPDF journal article, handout or slides
Club cells in adenocarcinoma and alveolar repair
Georgios Stathopoulos (Munich, Germany)
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WebcastSlide presentationPDF journal article, handout or slides
Young Investigator Session – The William MacNee Award

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WebcastSlide presentation
Uncovering the cells and genes responsible for salamander limb regeneration
Nicholas Leigh (Lund, Sweden)
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WebcastSlide presentationPDF journal article, handout or slides
Cell-matrix interactions in chronic lung disease
Janette K. Burgess (Groningen, Netherlands)
WebcastSlide presentationPDF journal article, handout or slides
WebcastSlide presentationPDF journal article, handout or slides
Regulation of cell fate and integrity by mechanical signals
Sara Wick­ström (Helsinki, Finland)
WebcastSlide presentationPDF journal article, handout or slides
WebcastSlide presentationPDF journal article, handout or slides
Lung organoids reveal epithelial-mesenchymal mechanisms of lung disease and potential therapy
Carla Kim (Boston, United States of America)
WebcastSlide presentationPDF journal article, handout or slides
WebcastSlide presentationPDF journal article, handout or slides
Mesenchymal stem cell therapy for severe emphysema
Pieter S. Hiemstra (Leiden, Netherlands)
WebcastSlide presentationPDF journal article, handout or slides
WebcastSlide presentationPDF journal article, handout or slides
Cellular reprogramming of cancer cells to antigen-presenting cells
Filipe Pereira (Lund, Sweden)
WebcastSlide presentationPDF journal article, handout or slides
WebcastSlide presentationPDF journal article, handout or slides
Awards announcement and conclusion
Reinoud Gosens (Groningen, Netherlands)
WebcastSlide presentation
WebcastSlide presentation
PP101 – Short-range interactions between fibrocytes and CD8+ T cells modulate the balance between tissue repair and destruction in COPD
Isabelle Dupin, France
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PP102 – A serum biomarker reflecting human neutrophil elastase degraded calprotectin is elevated in COPD and IPF
Annika Hummersgaard Hansen, Denmark
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PP103 – Dysregulation of ZFP36L1 and ZFP36L2 in asthma alters epithelial integrity and genome-wide glucocorticoid responses
Rocio Teresa Martinez-Nunez, United Kingdom
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PP104 – Whole transcriptome analysis on lungs of house dust mite-exposed IGF1Rdeficient mice provides new insights in allergic airway inflammation
Alfredo Urtubia, Spain
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PP105 – Single-cell transcriptome analysis reveals an anomalous epithelial variation and ectopic inflammatory response in COPD
Naoaki Watanabe, Japan
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PP106 – Identification of HuR-specific RNA interactome in TGFß1-activated fibroblasts in response to cigarette smoke
Sofia Winslow, Sweden
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PP107 – 3D printing aids simultaneous isolation of proximal and distal lung epithelial progenitors from individual mice
Hani N. Alsafadi, Sweden
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PP108 – Role of TRIM-16-mediated lysophagy in COPD pathogenesis
Yusuke Hosaka, Japan
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PP109 – Coxsackie and Adenovirus Receptor (CAR) controls lung epithelial cell responses to inflammation
Elena Ortiz Zapater, United Kingdom
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PP110 – Modulation of the TGF-ß-induced epithelial-to-mesenchymal transition by panselective PDE inhibitors in A549 cells
Katarzyna Wójcik-Pszczola, Poland
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PP111 – PGE2 and PGI2 restore defective lung epithelial progenitors induced by cigarette smoke
Xinhui Wu, Netherlands
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PP112 – Itaconate regulates responses to inhaled aeroallergen
Gesa Albers, United Kingdom
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PP113 – Epidermal growth factor receptor in airway remodelling during allergic airway disease – divergent roles during early life and adulthood?
Helen Stölting, United Kingdom
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PP114 – Mesenchymal stromal cells reduce house dust mite induced allergic airway inflammation in a humanised MIF expressing mouse model
Ian Hawthorne, Ireland
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PP115 – COL4A3 degradation predicts anti-IgE response in severe asthma
Markus Weckmann, Germany
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PP116 – Associations between pediatric asthma and adult lung diseases
Nirmin Juber, Taiwan
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PP117 – Household use of biomass fuel is associated with childhood wheeze and eczema: a cross sectional study of rural communities in Kandy, Sri Lanka
Olivia Lall, Australia
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PP118 – Ambient PM2.5 Exposure and Respiratory Disease Hospitalization in Kandy, Sri Lanka
Gayan Bowatte, Sri Lanka
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PP119 – COL4A3 expression in asthmatic epithelium depends on intronic methylation and ZNF263 binding
Sai Sneha Priya Nemani, Germany
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PP120 – Smoking alters gene expression and methylation patterns in asthma patient nasal epithelium
Karosham (Diren) Reddy, Australia
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PP121 – Gaq/11 and Ga12/13 promote pulmonary fibrosis by driving distinct myofibroblast functions
Amanda Goodwin, United Kingdom
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PP122 – AT2 cell delivery using rECM microcarriers for COPD treatment
Deniz Ali Bölükbas, Sweden
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PP123 – Dimethyl fumarate attenuates lung inflammation and oxidative stress induced by chronic exposure to diesel exhaust particles in mice
Isabella Cattani-Cavalieri, Netherlands
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PP124 – Establishment of a human in vitro model for airway epithelial repair and regeneration
Ashesh Chakraborty, Germany
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PP125 – Glycogen synthase kinase-3 inhibition by CHIR99021 promotes alveolar epithelial cell proliferation and lung regeneration in acute lung injury
Raquel Fernandes, Portugal
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PP126 – RANKL contributes to lung tissue repair via promoting type II epithelial cell proliferation
Habibie Habibie, Netherlands
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PP127 – Three-dimensional niches for the physiological-like expansion of a lung mesenchymal stromal cell subpopulation
Arturo Ibáñez Fonseca, Sweden
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PP128 – Investigating the role of vitamin A intake and retinoic acid signalling in lung homeostasis and repair-A multidisciplinary approach
Róisín Mongey, United Kingdom
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PP129 – Safety evaluation of cancer immunotherapy in a lung-on-chip model: the therapeutic FOLR1 targeting T Cell Bispecific antibody
Giulia Raggi, Switzerland
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PP130 – Spatial characteristics of CD169+ resident conducting airway macrophages during Aspergillus fumigatus-induced inflammation
Marina Shevchenko, Russia
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PP131 – Macrophages in lung adenocarcinoma
Giannoula Ntaliarda, Greece
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PP132 – Reversible fetal tracheal occlusion in mice: a novel transuterine method
Nilhan Torlak, Turkey
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PP133 – IGF1R acts in the tumor microenvironment as a cancer-promoting factor facilitating the implantation and progression of lung metastasis
Elvira Alfaro Arnedo, Spain
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PP134 – Mapping of Kras mutations during chemical carcinogenesis
Sabine Behrend, Germany
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PP135 – Mutational RNA signatures in environmentally-induced lung adenocarcinoma
Georgia A. Giotopoulou, Germany
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PP136 – Preclinical evaluation of IL-1ß inhibition against KRAS-mutant lung adenocarcinoma
Georgios Skiadas, Greece
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PP137 – Airway cells in adult lung homeostasis and carcinogenesis
Magda Spella, Greece
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PP138 – Regulation of PA200 in lung cancer
Ayse Seda Yazgili, Germany
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PP201 – Therapeutic targeting of iBALT induces lung regeneration in COPD
Thomas Conlon, Germany
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PP202 – Recreating the 3D environment for airway fibroblasts and epithelial cells with lung extracellular matrix derived hydrogels
Roderick H.J. de Hilster, Netherlands
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PP203 – Club cell functions as a Wnt-responsive progenitor for tissue repair in COPD
Yan Hu, USA
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PP205 – Effect of mTOR inhibition in a 3D in vitro model of alveolar epithelium and epithelial regeneration
Manuela Platé, United Kingdom
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PP206 – Modeling idiopathic pulmonary fibrosis using induced pluripotent stem cell-derived alveolar epithelial organoids
Victoria Ptasinski, Sweden
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PP207 – Targeting p16INK4a in alveolar type 2 cells to induce endogenous lung alveolar regeneration
Bruno Ribeiro Baptista, France
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PP208 – SRC family kinases modulate molecular pathways associated with mitochondrial dysfunction in idiopathic pulmonary fibrosis
Carmen Veith, Germany
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PP209 – Mitochondrial DNA stress activates MHC class I antigen presentation and CD8+ Tcell immunity: implications for pulmonary fibrosis
Xinyuan Wang, Germany
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PP211 – Galectin-3 is elevated following nintedanib treatment
Gali Epstein Shochet, Israel
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PP212 – The Anti-Fibrotic Drug Nintedanib Promotes Repair Macrophages
Carolin Koss, Germany
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PP213 – Adoptive transfer of hepatocyte growth factor transfected T cells in a bleomycin injured murine lung model
Seyran Mutlu, Switzerland
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PP214 – Human precision-cut lung slices generated from excess donor lungs as a model for IPF and drug screening
John Stegmayr, Sweden
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PP215 – The effect of long-term personal air pollution exposure on the inflammatory mediators in Idiopathic Pulmonary Fibrosis
Ioannis Tomos, Greece
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PP216 – Glucocorticoids exacerbate TGFß1 mediated fibrotic signalling in lung fibroblasts by inhibition of metalloproteinase expression and activity
Muzamil Majid Khan, Germany
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PP217 – Modeling idiopathic pulmonary fibrosis on a lung-on-chip
Lea de Maddalena, Switzerland
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PP218 – Direct effects of cigarette smoke in pulmonary arterial cells: Implications in arterial remodeling and vascular tone maintenance
Javier Sevilla-Montero, Spain
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PP219 – Development and Validation of a Novel Prognostic Nomogram for COPD patients with Pulmonary Hypertension
Dansha Zhou, China
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PP220 – Hypercoagulability in patients with stable COPD assessed by coagulation factor levels
Chris Kyriakopoulos, Greece
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PP221 – EZH2-dependent transcriptional complex promotes aberrant epithelial remodelling after injury
Huy Le, Germany
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PP222 – Forkhead Box F1 as a mediator of Wnt signaling in human lung endothelial cells
Gabriëla Edel, Netherlands
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PP223 – N-Acetyl cysteine rescues neonatal lethality caused by HRas/NRas deficiency by improving lung maturation and decreasing oxidative stress
Rocío Fuentes Mateos, Spain
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PP225 – Development of a 3D in vitro co-culture model of the airway mucosa using human primary cells
Cinta Iriondo, Netherlands
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PP226 – Decellularized extracellular matrix hydrogels for human airway organoid culture
Sinem Tas, Sweden
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PP227 – Paper-based biosensor for the detection of sepsis murine using MMP9 and a9ß6, integrons RI Class1 and R2 Class 2 peptides
Nuha Alekhmimi, Saudi Arabia
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PP228 – Chest CT findings on admission of COVID-19 pneumonia and its association with disease severity and duration of illness: a retrospective study
Eleanor Dela Pena, Philippines
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PP229 – Clinical profile of 116 patients undergoing post-COVID follow-up - A prospective study
Pranav Modi, India
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PP230 – Functional profiling and visualization of stromal cell dynamics in the influenza virus infected lung
Julie Worrell, United Kingdom
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PP231 – Released mediators in ex vivo 3D-model of lung fibrosis correspond to elevated serum biomarkers in IPF
Dimitrios Kalafatis, Sweden
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PP232 – IL11 negatively impacts adult lung alveolar organoid formation
Rosa K. Kortekaas, Netherlands
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PP233 – Crosstalk between lung fibroblasts and mast cells is modified by alveolar extracellular matrix and influences epithelial migration
Anna-Karin Larsson-Callerfelt, Sweden
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PP234 – Lung-on-a-chip device for modelling of ventilator induced lung injury
Emil Rehnberg, Sweden
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PP236 – Elastin-like-recombinamer cryogel as a platform for lung regeneration
Zackarias Söderlund, Sweden
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PP237 – D-dopachrome tautomerase contributes to lung epithelial repair via ACKR3- dependent Akt signalling
Shanshan Song, Netherlands
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PP238 – Role of mitochondrial function of lung mesenchymal stem cells in idiopathic pulmonary fibrosis
Joan Truyols, Spain
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PP239 – Decellularised porcine pleural patches for management of prolonged alveolar air leaks
Trisha Vikranth, United Kingdom
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PP240 – COL4A3 degradation is increased in severe, type 2 exacerbating asthmatics
Markus Weckmann, Germany
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PP301 – The role of the systemic inflammation in bronchiectasis exacerbation frequency
Kseniia Suska, Ukraine
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PP302 – The relationship between the level of C-reactive protein and the general cardiovascular risk in patients with COPD and hypertension
Olha Boiko, Ukraine
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PP303 – Effects of mild to moderate asthma in pregnancy on the wellbeing of mother and newborn; A case control study from Sri Lanka
Duminda Yasaratne, Sri Lanka
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PP304 – The effect of exercises on flat and sloping levels on muscle mass and functional capacity in chronic obstructive pulmonary disease patients
Samira Nakhaie, Iran
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PP305 – Can Hematological Ratios Predict Outcome of COVID-19 Patients? Egyptian Multicentric Study
Mai Aly, Egypt
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PP306 – Submicroscopic changes of type I alveolocytes in the early stages of experimental diabetes mellitus
Yuliya Fedorchenko, Ukraine
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PP307 – The role of microalbuminuria (MAB) in patients admitted for an Acute COPD Exacerbation (AECOPD)
Chris Kyriakopoulos, Greece
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PP308 – Endothelial injury in Chronic Obstructive Pulmonary Disease assessed by microalbuminuria (MAB) and von Willebrand factor levels and activity
Chris Kyriakopoulos, Greece
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PP309 – Effect of elexacaftor-tezacaftor-ivacaftor on pulmonary and endothelial function in a patient with advanced cystic fibrosis
Saša Rink, Slovenia
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PP310 – Association of testosterone with lung function in patients with chronic obstructive lung disease
Abir Hedhli, Tunisia
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PP311 – Nontypeable Haemophilus influenzae supresses SP-B and SP-C expression in alveolar epithelial type II cells
Hannah Sophie Stodden, Germany
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PP312 – Diagnosis of non severe pulmonary embolism
Salma Aït Batahar, Morocco
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PP313 – Agreement between expert sonographers and artificial intelligence in the evaluation of lung ultrasound data acquired from COVID-19 patients
Libertario Demi, Italy
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YI401 - A comprehensive guide to pulmonary mesenchymal populations in the healthy and IPF lung
Simon Coyle Rowan (Dublin, Ireland)
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YI402 - Host response towards decellularised lung extracellular matrix reinforced bioinks for 3D bioprinting lung tissue for transplantation
Martina M. De Santis (Lund, Sweden)
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YI403 - cAMP response element-binding protein mediates immune-evasion of KRASmutant lung adenocarcinoma
Georgia A. Giotopoulou (Munich, Germany)
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YI404 - Pluripotent stem cell derived airway cholinergic neurons for disease modelling of neuroplasticity in asthma
Pien Goldsteen (Groningen, Netherlands)
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YI405 - Use of differentiated primary human airway epithelial models to study SARSCoV-2 infection biology and pathogenesis
Ying Wang (Leiden, Netherlands)
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