The typical management plan for treatment for an exacerbation of asthma has mostly remained unchanged for 20 years, with systemic steroids and bronchodilators remaining the unavoidable cornerstones for treatment. Deaths due to asthma are rare occurrences in the hospital setting, which does not provide an incentive for improvements in treatment management. However, it is thought that ~50% of asthma deaths overall may be preventable. This has stimulated new research into the use of biologics, resulting in a promising new era where management strategies are likely to shift dramatically.

Cite as: Charriot J, Volpato M, Sueh C, et al. Asthma: treatment and prevention of pulmonary exacerbations. In: Burgel P-R, Contoli M, López-Campos JL, eds. Acute Exacerbations of Pulmonary Diseases (ERS Monograph). Sheffield, European Respiratory Society, 2017; pp. 129–146 [https://doi.org/10.1183/2312508X.10016416].