European Respiratory Journal (ERJ) - Current Issue

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Abstract
Development of allergic asthma is a complex process involving immune, neuronal and tissue cells. In the lung, Clara cells represent a major part of the “immunomodulatory barrier” of the airway epithelium.To understand the contribution of these cells to the inflammatory outcome of asthma, disease development was assessed using an adjuvant-free ovalbumin model. Mice were sensitised with subcutaneous injections of 10 µg endotoxin-free ovalbumin in conjunction with naphthalene-induced Clara cell dep... [View all]
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