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Improving asthma control in the harder-to-reach population
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Bronchial asthma as neurogenic paroxysmal inflammatory disease - high efficacy of antiepileptic drug oxcarbazepine in asthma monotherapy
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M. Lomia, M. Pruidze, Z. Chapichadze (Tbilisi, Georgia)
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Abstract
Purpose. Based on the assumption that bronchial asthma has certain neurogenic paroxysmal mechanism and links with other paroxysmal diseases - breath-holding spells, epilepsy, migraine and trigeminal neuralgia, we searched antiasthmatic activity of oxcarbazepine and EEG and neural signs frequency during asthma.
Methods.
Randomized, double-blind, placebo-controlled trial was performed in 46 patients. The EEG (brain-mapping) and neural signs also were searched.
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