Difficult-to-Treat Asthma

Difficult-to-Treat Asthma (Issue 51)
297
Severe asthma: the way forward
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Chung K.F., Bel E.H., Wenzel S.E.
Eur Respir Mon 2011; 51: 297-308
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Abstract
The publication of the first definitions more than 10 years ago has helped to focus attention on severe asthma and there has been progress in understanding about this condition. Severe asthma is heterogeneous in terms of its natural history, pattern of airflow obstruction, inflammatory component and therapeutic response to corticosteroid therapy, and it is necessary to define and validate its phenotypes. There have also been advances in understanding of the inflammatory process and the airway wa... [View all]

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