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 European Respiratory Journal (ERJ) - Archive

January (Issue 1 Volume 35)
124
Control of breathing in children with mild sleep apnoea: a 6-year follow-up study
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Rice A., Costy-Bennett S., Goodwin J. L., Quan S. F., Fregosi R. F.
Eur Respir J 2010; 35: 124-131		Full textPDF-fileAbstract

Abstract
We have previously shown that children (average age 9 yrs) with mildly elevated obstructive apnoea/hypopnoea indices (OAHI) retained CO2 at rest. Here, we report the results of a 6-yr follow-up study on 14 children from that study. Minute ventilation (V'E) and end-tidal CO2 partial pressure (PET,CO2) were measured during hypercapnic challenge. OAHI decreased from 7.5 +/- 4.7 eventsoh-1 at age 9 yrs to 2.5 +/- 1.8 eventsoh-1 at age 15 yrs (p<0.001), despite an increase in body mass index from 2... [View all]
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