Seminar and workshop: Molecular and Cellular aspects of Chronic Lung Disease, Rotterdam 2009

About
Research Seminars gather a small number (20 to 100) of well-established and preferably young investigators to address scientific topics in depth and help break new ground. Research Seminars take place over two days in easy-to-reach European cities. They are scientific Seminars involving recently published work and research in progress. Participation is fully supported by the budget granted by the ERS.
About  Show

Background

This workshop brought together experts using different animal models of lung pathology, letting them interact with young researchers in the field. Through a combination of lectures and group discussions on selected topics gave researchers better access to related technology and experience.

The purpose of this exercise was to generate synergy from the combined experience, which should lead towards:

  • Consensus protocols for the study of lung disease in animal models
  • An investigation of common mechanisms in different forms of chronic lung disease
  • Novel and combined approaches in the field of experimental lung disease
Background  Show

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 [+]  PDF journal article, handout or slides Cystic Fibrosis Lung disease, from animal models to experimental therapeutics.
B. Scholte (Rotterdam, The Netherlands)
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 [+]  PDF journal article, handout or slides A Transcriptional Network Controlling Normal Goblet Cell Differentiation and Mucous Production
J. Whitsett (Cincinnati, Oh, United States of America)
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Targeting Dendritic cells to better understand Asthma
B. Lambrecht (Gent, Belgium)
 [+]  PDF journal article, handout or slides Chronic epithelial injury in Diffuse Parenchymal Lung Diseases (DPLD) cellular consequences and therapeutic prospects
A. Guenther (Giessen, Germany)
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 [+]  PDF journal article, handout or slides Phenotypic Analysis of a Ferret Model of Cystic Fibrosis
J. Engelhardt (Iowa City, Il, United States of America)
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 [+]  PDF journal article, handout or slides Use of Airway Epithelial Cell Cultures in Inflammatory Lung Disease Research
P. Hiemstra (Leiden, The Netherlands)
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 [+]  PDF journal article, handout or slides Chronic Airway Inflammation promotes de novo Sensitization to Inhaled Allergen by Persistent Activation of Dendritic Cells
L. Van Rijt (Amsterdam , Netherlands)
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 [+]  PDF journal article, handout or slides Chronic lung disease in CF mouse models, role of macrophages, treatment with azithromycin
T. Leal (Brussels, Belgium)
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Mouse models of Bacterial Infection
A. Van Heeckeren (Cleveland, Oh , United States of America)
 [+]  PDF journal article, handout or slides 10 Effects of acute and chronic LPS exposure on the inflammatory response in CF mice
M. Egan (New Haven, Ct, United States of America)
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 [+]  PDF journal article, handout or slides 11 Procoagulant activity and signalling in fibroproliferative lung disease
R. Chambers (London, United Kingdom)
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 [+]  PDF journal article, handout or slides 12 Lung Embryology, congenital abnormalities
R. Rottier (Rotterdam, Netherlands)
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13 Modifier Genes in CF mouse and man
I. Bronsveld (Utrecht, Netherlands)
 [+]  PDF journal article, handout or slides 14 Noninvasive and invasive pulmonary function measurements in mice with obstructive and restrictive respiratory diseases
W. Janssens (Leuven, Belgium)
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15 Transcriptomics, microarrays and QPCR, data-mining
A. Stubbs (Rotterdam, Netherlands)
 [+]  PDF journal article, handout or slides 16 From Electrophysiology to Pathology
D. Sheppard, (Bristol, United Kingdom)
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 [+]  PDF journal article, handout or slides 17 The inhibitory effect of fenretinide on the expression of inflammatory cytokines, possible molecular target of the drug and its relevance to cystic fibrosis.
D. Radzioch (Montreal, Canada)
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 [+]  PDF journal article, handout or slides 18 Non-viral and viral gene transfer in ex vivo and in vivo lung models
U. Griesenbach (London, United Kingdom)
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 [+]  PDF journal article, handout or slides 19 CFTR correctors and potentiators: pre-clinical studies in mouse models for CF
M. Wilke (Rotterdam, Netherlands)
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 [+]  PDF journal article, handout or slides 20 Characterisation of a model that mimics aspects of the hyper-inflammatory response observed during an acute exacerbation of COPD.
K. Banner (Horsham, United Kingdom)
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 [+]  PDF journal article, handout or slides 21 Potential therapeutic use of 12-Lipoxygenase inhibitors in the treatment of mucus overproduction in cystic fibrosis
L. Touqui (Paris, France)
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