Genetics, epigenetics and exposomics: novel methods to study gene-by-environment interactions, Estoril 2015

About
Research Seminars gather a small number (20 to 100) of well-established and preferably young investigators to address scientific topics in depth and help break new ground. Research Seminars take place over two days in easy-to-reach European cities. They are scientific Seminars involving recently published work and research in progress. Participation is fully supported by the budget granted by the ERS.
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Background

The contribution of genetic factors to development of asthma and COPD is very complex and interactions between different genes, or between genes and the environment, complicate inferences even further. The number of studies incorporating gene-environment interactions is increasing and it becomes more and more clear that genetics do not explain all the inheritance associated with asthma and COPD and that environmental exposures such as cigarette smoking and air pollution can affect the susceptibility and severity of airways disease.

This Research Seminar gathered experts ranging from epidemiologists to mathematicians, from clinicians to environmental experts; and researchers involved or interested in studying the effects of genes and/or environmental exposures as determinants for onset and course of chronic respiratory disease.

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 [+]  PDF journal article, handout or slides Slide presentation The best statistical approaches for analysis of GWIS
Florence Demenais (Paris, France)
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 [+]  PDF journal article, handout or slides Slide presentation Implications of the exposome for exposure science
Jelle Vlaanderen (Utrecht, Netherlands)
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 [+]  PDF journal article, handout or slides Epigenetic effects of occupational exposure (nanomaterials); from the bench to the work floor
Peter Hoet (Heverlee, Belgium)
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 [+]  PDF journal article, handout or slides Slide presentation New possibilities in exposure assessment for microbial agents
Dick Heederik (Utrecht, Netherlands)
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 [+]  PDF journal article, handout or slides Transgenerational effects of exposures
Cecilie Svanes (Bergen, Norway)
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 [+]  PDF journal article, handout or slides From genetical genomics to system genetics: application in asthma/COPD
Luc Janss (Leiden, Netherlands)
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 [+]  PDF journal article, handout or slides Network-based gene-set enrichment analysis
Rosa Faner Canet (Barcelona, Spain)
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 [+]  PDF journal article, handout or slides Slide presentation Integrating it all: systems biology
Josep Roca (Barcelona, Spain)
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