International Congress Munich 2014



Novel approaches and evidence for drug development in respiratory diseases

Poster Discussion
Chairs: I. Vachier (Montpellier, France), B. Oliver (Sydney, Australia)


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 [+]  Congress or journal article abstract 3326 Dissociation between clinical trial inclusion and exclusion criteria for trials in severe asthma and the reality of the patient population
T. Brown, H. Rupani, C. Barber, S. Elliot, K. Gove, L. Lau, L. Hewitt, E. Ray, E. Aitken, S. Kerley, R. Kurukulaaratchy, C. Grainge, R. Djukanovic, A. Chauhan, P. Howarth (Portsmouth, Southampton, United Kingdom)
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 [+]  Congress or journal article abstract E-poster 3327 Gene set variation analysis of mRNA expression in bronchial biopsies from the U-BIOPRED asthma study
S. Pavlidis, A. Rowe, I. Adcock, K. Russell, I. Pandis, Y. K. Guo, B. DMeuldere, D. Lefaudeux, C. Auffray, R. Djukanovic, P. Howarth, F. Chung, M. Loza, N. Rao, F. Baribaud (High Wycombe, Buckinghamshire, London, Southampton, United Kingdom; Lyon, France; Springhouse, United States Of America)
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 [+]  Congress or journal article abstract 3328 Abediterol, a novel long-acting inhaled beta2-agonist, has a fast association rate and long residence time at human beta2 receptors
M. Miralpeix, M. Letosa, M. Aparici, C. Puig, A. Gavaldà, D. Vilella, I. Ramos (Barcelona, Spain)
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 [+]  Congress or journal article abstract 3329 Pharmacokinetics (PK), safety and tolerability of abediterol and mometasone furoate fixed- and free-dose combinations in healthy subjects
E. Jimenez, E. DeNoia, S. Ruiz, B. Seoane, E. Massana, G. De Miquel, C. Astbury (Barcelona, Spain; San Antonio, United States Of America)
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 [+]  Congress or journal article abstract 3330 Lung deposition analysis of two formulations of fluticasone/salmeterol HFA pMDI in stable asthma patients
J. De Backer, C. V. Holsbeke, W. Vos, S. Vinchurkar, J. Rebello, M. Mangale, W. De Backer (Kontich, Wilrijkstraat 10, 2650, Belgium; Mumbai, India)
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 [+]  Congress or journal article abstract 3331 Differential effects of budesonide and fluticasone propionate on bronchial epithelial barrier function
I. Heijink, M. Jonker, N. Ten Hacken, E. Telenga, D. Postma, M. Van den Berge (Groningen, Netherlands)
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 [+]  Congress or journal article abstract 3332 The anti-inflammatory effects of sulforaphane are not mediated by the Nrf2 pathway
A. Durham, E. Jazrawi, J. A. Rhodes, C. Williams, I. Kilty, P. Barnes, K. F. Chung, I. Adcock (London, United Kingdom; Cambridge, United States Of America)
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 [+]  Congress or journal article abstract 3333 Anti-inflammatory effects of targeted lung denervation in patients with COPD
L. Kistemaker, D. J. Slebos, H. Meurs, H. Kerstjens, R. Gosens (Groningen, Netherlands)
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 [+]  Congress or journal article abstract 3334 Long-lasting interaction study between RPL554 and glycopyrronium bromide on human isolated bronchi
L. Calzetta, M. Cazzola, C. Page, P. Rogliani, F. Facciolo, M. G. Matera (Rome, Naples, Italy; London, United Kingdom)
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 [+]  Congress or journal article abstract E-poster 3335 Pharmacological activities of roflumilast N-oxide, dexamethasone and formoterol in human neutrophils from healthy non-smokers and COPD patients
J. Milara, J. Lluch, A. Serrano, J. Freire, M. Qian, M. Alonso-Galicia, C. Sanz, R. Guijarro, J. Cortijo (Valencia, Spain; Jersey City, United States Of America)
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 [+]  Congress or journal article abstract E-poster 3336 Effectively targeting small airways using controlled inhalation for peripheral corticosteroid deposition
S. Canisius, K. Nocker, G. Scheuch, T. Hofmann (Gemünden, Germany)
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 [+]  Congress or journal article abstract 3337 Interaction between RPL554 and glycopyrronium bromide in small human airways
L. Calzetta, M. Cazzola, C. Page, P. Rogliani, F. Facciolo, M. G. Matera (Rome, Naples, Italy; London, United Kingdom)
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 [+]  Congress or journal article abstract 3338 Interaction between aclidinium bromide and formoterol fumarate in small human airways
M. Cazzola, L. Calzetta, C. P. Page, P. Rogliani, F. Facciolo, A. Gavaldà, M. G. Matera (Rome, Naples, Italy; London, United Kingdom; Barcelona, Spain)
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 [+]  Congress or journal article abstract E-poster 3339 Development of a lung slice methodology to study the mechanisms of lung uptake and lysosomal trapping
E. Bäckström, A. Lundqvist, P. Svanberg, E. Boger, P. Ewing, M. Hammarlund-Udenaes, M. Fridén (Uppsala, Mölndal, Sweden)
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 [+]  Congress or journal article abstract 3340 Development of a human COPD model-on-a-chip to mimic disease exacerbation (a small airway-on-a-chip model)
K. Hajipouran Benam, R. Villenave, C. Lucchesi, M. Mazur, G. Hamilton, D. Ingber (Boston, United States Of America)
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 [+]  Congress or journal article abstract 3341 Expression of CysLT2 receptors in asthmatic lung, and the roles in bronchoconstriction
T. Nabe, T. Sekioka, M. Kadode, M. Fujii, T. Abe, M. Horiba, S. Kohno, K. Kawabata (Osaka, Kyoto, Gifu, Japan)
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 [+]  Congress or journal article abstract E-poster 3342 miRNA-145 & SMAD3 expression in patients with COPD
L O’Leary, B. Tildy, I. Papazoglou, I.M. Adcock, K.F. Chung, M. Perry (London, United Kingdom)
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 [+]  Congress or journal article abstract E-poster 3343 Decametoxine efficiency in the treatment of infectious exacerbation of asthma
M. Gumeniuk, S. Panchuk (Kyiv, Ukraine)
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