GRACE Workshop on Lower Respiratory Tract Infections, Prague 2007

Target audience
Primary care and hospital physicians, researchers and public health specialists interested in better management of community-acquires LRTI.
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Educational aims
The GRACE project is designed around the broad theme of controlling antibiotic resistance in the context of community respiratory infections, since these are the major targets for much antibiotic prescribing. The complex nature of lower respiratory tract infections is reflected in the various diseases, syndromes, microbial pathogens and host responses. As such, these infections are responsible for much morbidity and the use of healthcare resources which in turn have significant economic implications.

This workshop provides in a shared session an overview on host-pathogen interactions in the lung and focuses subsequently in two parallel sessions either on the bacteriology of respiratory tract infections or on the epidemiology and the economic impact of common respiratory infections.
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 [+]  PDF journal article, handout or slides Slide presentation Webcast Multimedia files Introduction to host defences of the lung in health and disease
C. Greene (Dublin, Ireland)
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 [+]  PDF journal article, handout or slides Slide presentation Webcast Multimedia files Introduction to host-bacterial interaction - from colonisation to invasion
P. Hermans (Nijmegen, Netherlands)
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An overview of the cellular, molecular and cytokine response to exogenous agents
R. Schumann (Berlin, Germany)
 [+]  Slide presentation Webcast Multimedia files The immune response to acute lung infection - local and systemic
T. Welte (Hanover, Germany)
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 [+]  Slide presentation Webcast Multimedia files Research in progress - Why GRACE? The challenges faced by primary care clinicians in managing LRTI
T. Verheij (Utrecht, Netherlands)
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 [+]  Slide presentation Webcast Multimedia files Research in progress - Implementing the largest ever prospective clinical study of LRTI in the community
J. Nuttall (Cardiff, United Kingdom)
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 [+]  Slide presentation Webcast Multimedia files Research in progress - First GRACE findings
K. Hood (Cardiff, United Kingdom)
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 [+]  Slide presentation Research in progress - GRACE studies: the next steps
T. Verheij (Utrecht, Netherlands)
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 [+]  PDF journal article, handout or slides Slide presentation Webcast Multimedia files Streptococcus pneumoniae: a model for acute lung infection
T. Van Der Poll (Amsterdam, Netherlands)
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 [+]  PDF journal article, handout or slides Slide presentation Webcast Multimedia files 10 Host response to chronic lung infection
G. Rohde (Bochum, Germany)
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 [+]  Slide presentation Webcast Multimedia files 11 Mycobacterium tuberculosis: a model for chronic lung infection
R. Bals (Marburg, Germany)
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 [+]  PDF journal article, handout or slides 12 Bacterial quorum sensing and lung infection
M. Camara (Nottingham, United Kingdom)
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 [+]  PDF journal article, handout or slides Slide presentation 13 An introduction to the microbial epidemiology of community-acquired LRTI
M. Woodhead (Manchester, United Kingdom)
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 [+]  PDF journal article, handout or slides Slide presentation 14 Current and future microbiological laboratory investigation of LRTI
G. Ieven (Edegem, Belgium)
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 [+]  PDF journal article, handout or slides Slide presentation 15 Streptococcus pneumoniae – a biological and genetic profile
B. Henriques-Normark (Stockholm, Sweden)
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16 Haemophilus influenzae – a biological and genetic profile
D. Crook (Oxford, United Kingdom)
 [+]  PDF journal article, handout or slides Slide presentation 17 The application of mathematical modelling in profiling community LRTI
D. Smith (Cambridge, United Kingdom)
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 [+]  PDF journal article, handout or slides Slide presentation Webcast Multimedia files 18 The impact of environmental pollutants on lung infections
G. Viegi (Pisa, Italy)
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 [+]  PDF journal article, handout or slides Slide presentation Webcast Multimedia files 19 Acute bronchitis: impact on antibiotic use and misuse
T. Verheij (Utrecht, Netherlands)
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 [+]  PDF journal article, handout or slides Slide presentation Webcast Multimedia files 20 Chronic bronchitis from the stable phase to exacerbation: cost of failure and management
M. Miravitlles (Barcelona, Spain)
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 [+]  PDF journal article, handout or slides Slide presentation Webcast Multimedia files 21 Legionella, Mycoplasma and Chlamydia - contrasting features of intracellular pathogens
F. Blasi (Milan, Italy), P. Tarsia (Milan, Italy)
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 [+]  PDF journal article, handout or slides 22 Mycobacterium tuberculosis - genetic and molecular markers of infection
F. Drobniewski (London, United Kingdom)
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 [+]  Slide presentation Webcast Multimedia files 23 Anaerobic bacteria and the lung
E. Nagy (Szeged, Hungary)
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 [+]  Slide presentation Webcast Multimedia files 24 Staphylococcus aureus – a microbiological profile of an emerging respiratory pathogen
M. Bonten (Utrecht, Netherlands)
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 [+]  PDF journal article, handout or slides Slide presentation 25 Asthma and infection: new epidemiology and new aetiologies
A. Papi (Ferrara, Italy)
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 [+]  PDF journal article, handout or slides Slide presentation Webcast Multimedia files 26 Cystic fibrosis in children and adults: is the social and economic impact changing?
M. Bakker (Rotterdam, Netherlands)
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 [+]  PDF journal article, handout or slides Slide presentation Webcast Multimedia files 27 The epidemiology and impact of Streptococcus pneumoniae in different populations. Is vaccine changing the natural history?
A. Ortqvist (Stockholm, Sweden)
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 [+]  PDF journal article, handout or slides Slide presentation Webcast Multimedia files 28 Community-acquired pneumonia: profiling the healthcare and economic burden
M. Woodhead (Manchester, United Kingdom)
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