Lung Science Conference - Biology of gene-environment interactions in the lung, Estoril 2010

About

The ERS Lung Science Conference is important for both scientists and clinicians with an interest in the basis of lung disease.

The success of the yearly conference depends on the creation of the right dialogue between young European post-doctoral scientists and established investigators. Participant numbers are limited and a selection process is used to ensure that the very best are chosen in order to maintain the very highest uality of research.

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Educational aims
  • To present the very best of international lung science research
  • To highlight new discoveries likely to impact on the future of respiratory medicine
  • To encourage debate and interaction between young postdoctoral scientists and established investigators
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Plenary Lecture: Gene environment interactions; the model of alpha1-antitrypsin deficiency
D. Lomas (Cambridge, United Kingdom)
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Genes, environment and lung disease
J. Kere (Huddinge, Sweden)
 [+]  PDF journal article, handout or slides Oral presentation: Potential of ACE2 as a therapeutic target for pulmonary hypertension
M. Raizada (Gainesville, United States of America)
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The genetic basis of environmental lung disease
S. Kleeberger (Baltimore, United States of America)
 [+]  Slide presentation PDF journal article, handout or slides Multimedia files Webcast Oral presentation: New insights and therapeutically strategies for emphysema and COPD: the growth factors KGF and TGF?-1
A. Ö. Yildirim, M. Vandana, G. John, B. Müller, H. Fehrenbach (Borstel, Germany)
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Epigenetics and smoking in the development of lung cancer
S. Belinsky (Albuquerque, United States of America)
 [+]  Slide presentation PDF journal article, handout or slides Multimedia files Webcast Oral presentation: Epigenetic mechanism involved in smoke-induced persistent elevation of MUC5AC
R. Wu, A. Loukoianov, S. Statt, P. Lee, P. Thai, M. Chang (Davis, United States of America)
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Gene expression in smoking related lung disease
A. Spira (Boston, United States of America)
 [+]  PDF journal article, handout or slides Oral presentation: Exogenous administration of leptin restores the skewed inflammatory response in cigarette smoke-exposed ob/ob mice
J.H.J. Vernooy, L. Zabeau, J. Tavernier, G.F. Joos, G.G. Brusselle, E.F.M. Wouters, K.R. Bracke (Ghent, Belgium)
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10 Pulmonary alveolar proteinosis
B. Trapnell (Cincinnati, United States of America)
 [+]  PDF journal article, handout or slides 11 Oral presentation: Genetic or pharmacologic inhibition of ATX stimulates LPS-induced pulmonary inflammation
N. Oikonomou, A. Thanasopoulou, A. Kotanidou, G.D. Prestwich, V. Aidinis (Salt Lake City, United States of America)
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12 Hyper IgE syndrome and pulmonary infection
B. Grimbacher (London, United Kingdom)
 [+]  PDF journal article, handout or slides 13 Oral presentation: SOD3 protects cigarette smoke-induced emphysema associated with reduction of extracellular matrix fragmentation in mice
H. Yao, G. Arunachalam, S. Chung, J. Hwang, I. Sundar, V. Kinnula, J. Crapo, I. Rahman (Denver, Denver)
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14 Getting scientists and physicians to talk to each other
G. Laurent (London, United Kingdom)
 [+]  Slide presentation PDF journal article, handout or slides Multimedia files Webcast 15 Genes, mechanisms and new therapies for asthma
W. Cookson (London, United Kingdom)
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 [+]  PDF journal article, handout or slides 16 Oral presentation: Role of B-lymphocytes in a mouse model of chemical-induced asthma Innate immunity and the development of atopy
V. De Vooght, K. Luyts, S. Haenen, B. Nemery, P.H.M. Hoet, J.A.J. Vanoirbeek (Leuven, Belgium)
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 [+]  Slide presentation PDF journal article, handout or slides Multimedia files Webcast 17 Innate immunity and the development of atopy
T. Sigsgaard (Aarhus, Denmark)
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 [+]  Slide presentation PDF journal article, handout or slides Multimedia files Webcast 18 Oral presentation: Altered airway epithelial gene expression determines the lung remodeling response to environmental allergens; role of activin
L. Gregory, S. Pegorier, S. Mathie, C.P. Jones, C. Lloyd (London, United Kingdom)
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 [+]  Slide presentation PDF journal article, handout or slides Multimedia files Webcast 19 Genetics of childhood versus adult asthma: common and unique factors
M. Kabesch (Hannover, Germany)
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 [+]  PDF journal article, handout or slides 20 Oral presentation: Surfactant protein-B 121ins2 heterozygosity, reduced pulmonary function and COPD in smokers
M. Bækvad-Hansen, M. Dahl, A. Tybjærg-Hansen, B.G. Nordestgaard (Copenhagen, Denmark)
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 [+]  Slide presentation PDF journal article, handout or slides Multimedia files Webcast 21 Oral presentation: Gene-gene interaction between ITGB3 and TLR2 in sensitization to mold allergens among adults with asthma
L.A.M. Smit, E. Bouzigon, J. Bousquet, G. Doekes, N. Le Moual, R. Nadif, I. Pin, F. Demenais, F. Kauffmann, V. Siroux (Grenoble, France)
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 [+]  PDF journal article, handout or slides 22 Oral presentation: Vitamin D binding protein is functionally important in airway infections
A. Wood, C. Bassford, S. Rathnam, P. Rajesh, R. Stockley, D. Thickett (Birmingham, United Kingdom)
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 [+]  PDF journal article, handout or slides 23 Oral presentation: Role of HIF-1? on airway remodelling induced by house dust mite
C.P. Jones, S.M. Rankin, C.M. Lloyd (London, United Kingdom)
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 [+]  PDF journal article, handout or slides 24 Oral presentation: Role of neutrophil serine proteases in the pathogenesis of cigarette smoke-induced emphysema
N. Guyot, J. Wartelle, A. Belaaouaj (Reims, France)
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25 Inflammatory mechanisms in acute lung injury
J. Garcia (Chicago, Il, United States of America)
 [+]  PDF journal article, handout or slides 26 Oral presentation: Inhibition of innate host defense in airway epithelial cells by cigarette smoke in an in vitro infection model caused by suppression of NF-kB activation
C. Herr, C. Beisswenger, C. Vogelmeier, R. Bals (Marburg, Germany)
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 [+]  Slide presentation PDF journal article, handout or slides Multimedia files Webcast 27 Genetic basis of idiopathic interstitial pneumonia
D. Schwartz (Denver, United States of America)
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 [+]  PDF journal article, handout or slides 28 Oral presentation: Protease-activated receptor-2 plays a pivotal role in pulmonary fibrosis by inducing myofibroblast differentiation and tissue factor up-regulation
K. Borensztajn, P. Bresser, J. von der Thusen, C. van der Loos, B. van der Blink, M. den Bakker, J. Daalhuisen, A. Groot, M. Peppelenbosch, A. Spek (Groningen, Netherlands)
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 [+]  PDF journal article, handout or slides PDF journal article, handout or slides Webcast 29 Targeting CFTR as a therapy for cystic fibrosis
M. Amaral (Lisbon, Portugal)
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 [+]  PDF journal article, handout or slides 30 Oral presentation: Neutrophil elastase plays a dual role in host lung defense against Pseudomonas aeruginosa infection
J. Wartelle, R. Benabid, N. Guyot, A. Belaaouaj (Reims, France)
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31 Pursuing genetic and environmental modifiers in cystic fibrosis
J. Collaco (Baltimore, Md, United States of America)
 [+]  PDF journal article, handout or slides 32 Poster Presentation - abstracts
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